phenobarbital has been researched along with Rachitis in 36 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital treatment was also attended by a decrease in the intrahepatic content of [(3)H]vitamin D(3) (11." | 1.26 | Phenobarbital-induced alterations in the metabolism of [3H]vitamin D3 by the perfused rachitic rat liver in vitro. ( Avioli, LV; Baran, DT; Fausto, AC; Karl, I; Roberts, ML, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (94.44) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Awa, HD | 1 |
| Chelo, D | 1 |
| Kinkela, MN | 1 |
| Ndombo, PO | 1 |
| Akın, L | 1 |
| Kurtoğlu, S | 1 |
| Yıldız, A | 1 |
| Akın, MA | 1 |
| Kendirici, M | 1 |
| DUNDAS, JB | 1 |
| Aujard, Y | 1 |
| Ponsot, G | 1 |
| Livet, MO | 1 |
| Hausser, C | 1 |
| Schmelck, PH | 1 |
| Pomarede, F | 1 |
| Rappaport, R | 1 |
| Ishitsu, T | 1 |
| Matsuda, I | 1 |
| Seino, Y | 1 |
| Kann, H | 1 |
| Mogorianu, PD | 1 |
| Pshenko, LG | 1 |
| Shafer, RB | 1 |
| Nuttall, FQ | 1 |
| Norman, AW | 1 |
| Bayless, JD | 1 |
| Tsai, HC | 1 |
| Baran, DT | 1 |
| Fausto, AC | 1 |
| Roberts, ML | 1 |
| Karl, I | 1 |
| Avioli, LV | 1 |
| Teotia, M | 2 |
| Teotia, SP | 2 |
| Singh, RK | 1 |
| Gascon-Barré, M | 1 |
| Côté, MG | 1 |
| Liakakos, D | 1 |
| Papadopoulos, Z | 1 |
| Vlachos, P | 1 |
| Boviatsi, E | 1 |
| Varonos, DD | 1 |
| Montaguti, A | 1 |
| Biasini, G | 1 |
| Winnacker, JL | 1 |
| Yeager, H | 1 |
| Saunders, JA | 1 |
| Russell, B | 1 |
| Anast, CS | 1 |
| Morava, E | 1 |
| Gergely, A | 1 |
| Tarján, R | 1 |
| Klein, GL | 1 |
| Florey, JB | 1 |
| Goller, VL | 1 |
| Larese, RJ | 1 |
| Van Meter, QL | 1 |
| Schütze, I | 1 |
| Salomon, B | 1 |
| Thal, W | 1 |
| Leonidas, JC | 1 |
| Brill, PW | 1 |
| Waldman, N | 1 |
| Silver, J | 1 |
| Neale, G | 1 |
| Davies, D | 1 |
| Breckenridge, A | 1 |
| Thompson, GR | 1 |
| Lücking, T | 1 |
| Delling, G | 1 |
| Verma, IC | 1 |
| Khanna, AR | 1 |
| Reynolds, EH | 1 |
| Livingston, S | 1 |
| Pauli, LL | 1 |
| Bowden, AN | 1 |
| Ballow, M | 1 |
| Margolis, CZ | 1 |
| Schachtel, B | 1 |
| Hsia, YE | 1 |
| Burckhardt, P | 1 |
| Slomic, A | 1 |
| Szöts, F | 1 |
| Lifshitz, F | 1 |
| Maclaren, NK | 1 |
| Latorre, H | 1 |
| Kenny, FM | 1 |
| Medlinsky, HL | 1 |
| Spirer, Z | 1 |
| Weintraub, M | 1 |
| Lerman, P | 1 |
| Shor, S | 1 |
| Boagir, N | 1 |
| Borgstedt, AD | 1 |
| Bryson, MF | 1 |
| Young, LW | 1 |
| Forbes, GB | 1 |
| Dennis, NR | 1 |
| Lussier-Lazaroff, J | 1 |
| Fletcher, BD | 1 |
| Matthes, A | 1 |
2 reviews available for phenobarbital and Rachitis
| Article | Year |
|---|---|
[Phenobarbital-induced forms of rickets].
Topics: Adolescent; Adult; Alkaline Phosphatase; Calcium; Child; Child, Preschool; Depression, Chemical; Fem | 1980 |
Vitamin D and rickets.
Topics: Acidosis, Renal Tubular; Animals; Bone and Bones; Bone Neoplasms; Calcification, Physiologic; Dihydr | 1973 |
1 trial available for phenobarbital and Rachitis
| Article | Year |
|---|---|
Serum alkaline phosphatase and urinary hydroxyproline values in children receiving phenobarbital with and without vitamin D.
Topics: Adolescent; Alkaline Phosphatase; Bone and Bones; Calcium; Child; Child, Preschool; Collagen; Drug T | 1975 |
33 other studies available for phenobarbital and Rachitis
| Article | Year |
|---|---|
[Patent rickets disclosed by loss of convulsion control in a boy with cerebral palsy].
Topics: Anticonvulsants; Calcium; Carbamazepine; Cerebral Palsy; Child, Preschool; Diazepam; Epilepsy; Human | 2013 |
Vitamin D deficiency rickets mimicking pseudohypoparathyroidism.
Topics: Anticonvulsants; Calcium; Diagnosis, Differential; Humans; Infant; Male; Phenobarbital; Phosphates; | 2010 |
LOWE'S SYNDROME.
Topics: Acidosis; Albuminuria; Alkalies; Anti-Bacterial Agents; Blood; Bone Diseases; Calcium; Cataract; Chi | 1964 |
[Rickets. A rare complication of anti-epileptic treatments. Report of two cases in children].
Topics: Anticonvulsants; Black People; Calcifediol; Child; Contraindications; Drug Monitoring; Electroenceph | 1976 |
[Rickets in a child due to the combination of phenobarbital and valproic acid].
Topics: Drug Therapy, Combination; Female; Humans; Infant; Phenobarbital; Rickets; Valproic Acid | 1981 |
Anticonvulsant-induced rickets associated with renal tubular acidosis and normal level of serum 1,25-dihydroxyvitamin D.
Topics: Acetazolamide; Acidosis, Renal Tubular; Anticonvulsants; Calcitriol; Child; Female; Humans; Phenobar | 1981 |
Calcium and folic acid absorption in patients taking anticonvulsant drugs.
Topics: Adult; Aged; Calcium; Cholecalciferol; Epilepsy; Folic Acid; Humans; Male; Middle Aged; Osteomalacia | 1975 |
Biologic effects of short-term phenobarbital treatment on the response to vitamin D and its metabolites in the chick.
Topics: Animals; Biological Assay; Bone and Bones; Bone Resorption; Calcium; Chickens; Cholecalciferol; Dihy | 1976 |
Phenobarbital-induced alterations in the metabolism of [3H]vitamin D3 by the perfused rachitic rat liver in vitro.
Topics: Animals; Cholecalciferol; Dose-Response Relationship, Drug; In Vitro Techniques; Liver; Male; Micros | 1979 |
Rickets in tuberous sclerosis from anticonvulsant drugs.
Topics: Adolescent; Anticonvulsants; Child; Humans; Male; Phenobarbital; Phenytoin; Rickets; Tuberous Sclero | 1977 |
Influence of phenobarbital and diphenylhydantoin on the healing of rickets in the rat.
Topics: Animals; Calcification, Physiologic; Male; Phenobarbital; Phenytoin; Rats; Rickets; Vitamin D | 1978 |
Genetic aspects of nutritional rickets.
Topics: Adolescent; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Long-Term Care; Phenobarbital; | 1976 |
Rickets in children receiving anticonvulsant drugs. Biochemical and hormonal markers.
Topics: Adolescent; Anticonvulsants; Calcium; Child; Child, Preschool; Drug Combinations; Epilepsy; Evaluati | 1977 |
Influence of dietary cadmium and copper on the rachitogenic effect of some anticonvulsants in rats.
Topics: Animals; Bone and Bones; Cadmium; Calcium; Copper; Diet; Female; Male; Phenobarbital; Phenytoin; Rat | 1977 |
Multiple vitamin deficiencies in association with chronic anticonvulsant therapy.
Topics: Anticonvulsants; Ascorbic Acid Deficiency; Avitaminosis; Beriberi; Child, Preschool; Female; Heart D | 1977 |
[Distinct rickets during anticonvulsant long-term therapy].
Topics: Child, Preschool; Enzyme Induction; Epilepsy, Tonic-Clonic; Female; Humans; Phenobarbital; Phenytoin | 1973 |
Antiepileptic therapy and rickets in children.
Topics: Adolescent; Anticonvulsants; Barbiturates; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, To | 1973 |
The effect of phenobarbitone-induction on vitamin D metabolism.
Topics: Animals; Carbon Isotopes; Cholecalciferol; Enzyme Induction; Liver; Microsomes, Liver; Phenobarbital | 1972 |
[Severe rachitic osteopathy during long-term anticonvulsant treatment].
Topics: Administration, Oral; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Carbamazepine; Child; | 1973 |
Iatrogenic disorders in epilepsy.
Topics: Adrenal Insufficiency; Anemia, Macrocytic; Animals; Anticonvulsants; Cats; Cerebellar Diseases; Drug | 1970 |
Letter: Anticonvulsants and vitamin D metabolism.
Topics: Child; Drug Therapy, Combination; Epilepsy; Humans; Osteomalacia; Phenobarbital; Phenytoin; Primidon | 1974 |
Progressive familial intrahepatic cholestasis.
Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts, Intrahepatic; C | 1973 |
[Osteomalacia: new aspects of pathogenesis and treatment].
Topics: Calcium; Humans; Hydantoins; Hyperparathyroidism; Osteomalacia; Phenobarbital; Phosphorus; Rickets; | 1973 |
[Severe osteomalacic rickets induced by antiepileptic drugs. Literature review apropos of a case].
Topics: Child; Child, Preschool; Humans; Male; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Rickets; V | 1973 |
Vitamin D-dependent rickets in institutionalized, mentally retarded children receiving long-term anticonvulsant therapy. I. A survey of 288 patients.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Calcium; Child; Child, Preschool; Female; Humans; | 1973 |
Rickets precipitated by anticonvulsant drugs in a child receiving prophylactic vitamin D.
Topics: Adolescent; Alkaline Phosphatase; Calcium; Epilepsy; Female; Humans; Ilium; Phenobarbital; Phenytoin | 1973 |
High-dosage intravenous calcium therapy for osteoporosis and osteomalacia in anticonvulsant therapy with hypomobilization.
Topics: Alkaline Phosphatase; Calcium; Child; Child, Preschool; Female; Humans; Infant; Osteomalacia; Osteop | 1974 |
Rickets associated with anticonvulsant medication.
Topics: Alkaline Phosphatase; Calcium; Child, Preschool; Female; Humans; Phenobarbital; Phenytoin; Phosphoru | 1974 |
[Rickets and osteomalacia induced by anticonvulsant drugs].
Topics: Anticonvulsants; Epilepsy; Humans; Hydantoins; Israel; Osteomalacia; Phenobarbital; Rickets; Vitamin | 1974 |
Long-term administration of antiepileptic drugs and the development of rickets.
Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Diazepam; Ethosuximide; Female; Gluconates; Humans; | 1972 |
Rickets following anticonvulsant therapy.
Topics: Child, Preschool; Humans; Infant; Male; Phenobarbital; Phenytoin; Primidone; Rickets; Vitamin D | 1972 |
Rickets and anticonvulsant therapy in children: a roentgenologic investigation.
Topics: Adolescent; Anticonvulsants; Benzazepines; Child; Dextroamphetamine; Diazepam; Ethosuximide; Female; | 1971 |
[Therapy of occasional convulsions in children and adolescents].
Topics: Adolescent; Age Factors; Anticonvulsants; Calcium; Child; Humans; Infant, Newborn; Infant, Newborn, | 1969 |