phenobarbital has been researched along with Proteinuria in 6 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " PB pretreatment also enhanced some monitored renal effects of a toxic dose (0." | 1.29 | Effect of microsomal enzyme modulators on N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS)-induced nephrotoxicity in the Fischer 344 rat. ( Anestis, DK; Beers, KW; Brown, PI; Nicoll, DW; Rankin, GO, 1993) |
| "In phenobarbital-pretreated rats, MMPS administration had little effect on any renal functional parameter measured or urological morphology." | 1.28 | Role of para-hydroxylation in phensuximide-induced urotoxicity in the Fischer 344 rat. ( Anestis, DK; Beers, KW; Brown, PI; Hubbard, JL; Nicoll, DW; Rankin, GO; Shih, HC, 1992) |
| "As phenobarbital treatment in young rats enhanced the symptoms of nephrotoxicity and metyrapone treatment in adult rats decreased the symptoms of nephrotoxicity, age-dependent differences in chromate nephrotoxicity may be linked to an increase in the enzymatic reduction of Cr(VI) with age." | 1.28 | Influence of metyrapone and phenobarbital on sodium dichromate nephrotoxicity in developing rats. ( Appenroth, D; Bräunlich, H; Friese, KH; Gambaryan, S, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Appenroth, D | 2 |
| Beers, KW | 2 |
| Nicoll, DW | 2 |
| Anestis, DK | 2 |
| Brown, PI | 2 |
| Rankin, GO | 2 |
| Shih, HC | 1 |
| Hubbard, JL | 1 |
| Gambaryan, S | 1 |
| Friese, KH | 1 |
| Bräunlich, H | 1 |
| Haller, J | 1 |
| Lindheimer, MD | 1 |
| Roux, J | 1 |
6 other studies available for phenobarbital and Proteinuria
| Article | Year |
|---|---|
Ontogenic changes in the nephrotoxicity of chromate correlate with the glutathione oxidoreduction system.
Topics: Acetylcysteine; Aging; Animals; Chromates; Female; Glutaredoxins; Glutathione; Kidney; Male; Oxidati | 1994 |
Effect of microsomal enzyme modulators on N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS)-induced nephrotoxicity in the Fischer 344 rat.
Topics: Animals; Body Weight; Cobalt; Drug Synergism; Fungicides, Industrial; Injections, Intraperitoneal; K | 1993 |
Role of para-hydroxylation in phensuximide-induced urotoxicity in the Fischer 344 rat.
Topics: Animals; Biotransformation; Blood Urea Nitrogen; Drinking; Eating; Hematuria; Hydroxylation; Kidney; | 1992 |
Influence of metyrapone and phenobarbital on sodium dichromate nephrotoxicity in developing rats.
Topics: Aging; Animals; Chromates; Chromium; Cromolyn Sodium; Female; Kidney; Kidney Diseases; Kidney Tubule | 1990 |
[Therapy of EPH gestosis].
Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans; | 1973 |
Role of posture in sodium, water, and potassium homeostasis of an abnormal pregnancy.
Topics: Adolescent; Aminohippuric Acids; Blood Pressure; Creatinine; Diet Therapy; Diuresis; Female; Glomeru | 1970 |