phenobarbital has been researched along with Premenstrual Syndrome in 3 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Premenstrual Syndrome: A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A placebo-controlled, randomized, double-blind, parallel group study in hospital and general practice has shown that a combination of belladonna alkaloids, ergotamine tartrate, and phenobarbitone (Bellergal) was effective in treating troublesome symptoms of the premenstrual syndrome of which fatigue, tender breasts, nervousness, irritability, lethargy and listlessness were improved to a statistically significant degree." | 5.04 | Treatment of the premenstrual syndrome. ( Huntington, KM; Robinson, K; Wallace, MG, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Navrátil, K | 1 |
| Campbell, JJ | 1 |
| McNamara, ME | 1 |
| Robinson, K | 1 |
| Huntington, KM | 1 |
| Wallace, MG | 1 |
1 trial available for phenobarbital and Premenstrual Syndrome
| Article | Year |
|---|---|
Treatment of the premenstrual syndrome.
Topics: Adolescent; Adult; Belladonna Alkaloids; Clinical Trials as Topic; Drug Combinations; Ergotamine; Fe | 1977 |
2 other studies available for phenobarbital and Premenstrual Syndrome
| Article | Year |
|---|---|
[New drugs. Premenstrin. (Tablets)].
Topics: Caffeine; Ergotamine; Female; Guaifenesin; Phenobarbital; Premenstrual Syndrome; Tablets | 1966 |
A case of phenobarbital behavioral toxicity presenting as a menstrually related mood disorder.
Topics: Adult; Depressive Disorder; Diagnosis, Differential; Epilepsy; Female; Humans; Intellectual Disabili | 1993 |