phenobarbital has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 1 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A possible pharmacokinetic interaction between teniposide and anticonvulsant medications was evaluated in pediatric patients." | 1.28 | Increased teniposide clearance with concomitant anticonvulsant therapy. ( Baker, DK; Christensen, ML; Evans, WE; Pui, CH; Relling, MV; Rodman, JH, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, DK | 1 |
| Relling, MV | 1 |
| Pui, CH | 1 |
| Christensen, ML | 1 |
| Evans, WE | 1 |
| Rodman, JH | 1 |
1 other study available for phenobarbital and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Increased teniposide clearance with concomitant anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Chromatography, High Pressure Liquid; Drug Int | 1992 |