phenobarbital has been researched along with Pre-Eclampsia in 20 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The risks of preeclampsia (adjusted odds ratio [OR] 1." | 1.35 | Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes. ( Fraser, W; Olatunbosun, O; Walker, M; Wen, SW; Yang, Q; Zhou, J, 2008) |
| "Pregnancies complicated by severe preeclampsia in the second trimester are associated with a high incidence of perinatal morbidity and mortality." | 1.27 | Maternal and perinatal outcome of conservative management of severe preeclampsia in midtrimester. ( Abdella, TN; Anderson, GD; Brooks, TF; Sibai, BM; Spinnato, JA; Taslimi, M, 1985) |
| "22 patients with severe preeclampsia-eclampsia were treated in our Intensive Care Unit from 1972 to 1978." | 1.26 | [Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)]. ( Larsen, R; Radke, J; Turner, E, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (90.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wen, SW | 1 |
| Zhou, J | 1 |
| Yang, Q | 1 |
| Fraser, W | 1 |
| Olatunbosun, O | 1 |
| Walker, M | 1 |
| HANS, SF | 1 |
| KOPELMAN, H | 1 |
| MENZIES, DN | 1 |
| LAWSON, JG | 1 |
| Radford, AJ | 1 |
| Dow, R | 1 |
| COBO, E | 1 |
| Philbert, A | 1 |
| Dam, M | 1 |
| Larsen, R | 1 |
| Turner, E | 1 |
| Radke, J | 1 |
| Keegan, KA | 1 |
| Paul, RH | 1 |
| Broussard, PM | 1 |
| McCart, D | 1 |
| Smith, MA | 1 |
| Kuban, KC | 2 |
| Leviton, A | 2 |
| Pagano, M | 2 |
| Fenton, T | 1 |
| Strassfeld, R | 1 |
| Wolff, M | 1 |
| Brown, ER | 1 |
| Krishnamoorthy, KS | 1 |
| Allred, EN | 1 |
| Sibai, BM | 1 |
| Taslimi, M | 1 |
| Abdella, TN | 1 |
| Brooks, TF | 1 |
| Spinnato, JA | 1 |
| Anderson, GD | 1 |
| Horrobin, DF | 1 |
| Walker, W | 1 |
| Hughes, MI | 1 |
| Barton, M | 1 |
| Powell, J | 1 |
| Waterhouse, J | 1 |
| Culley, P | 1 |
| Wood, B | 1 |
| Haller, J | 1 |
| Rumack, BH | 1 |
| Walravens, PA | 1 |
| Jalling, B | 1 |
| Boréus, LO | 1 |
| Kållberg, N | 1 |
| Agurell, S | 1 |
| Urzaiz Jiménez, C | 1 |
| Cárdenas Ríos, G | 1 |
| Esquivel Sansores, C | 1 |
| Jouppila, P | 1 |
| Suonio, S | 1 |
1 review available for phenobarbital and Pre-Eclampsia
| Article | Year |
|---|---|
The epileptic mother and her child.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Fetal | 1982 |
2 trials available for phenobarbital and Pre-Eclampsia
| Article | Year |
|---|---|
Maternal toxemia and neonatal germinal matrix hemorrhage in intubated infants less than 1751 g.
Topics: Cerebral Hemorrhage; Clinical Trials as Topic; Female; Humans; Infant, Low Birth Weight; Infant, New | 1988 |
The effect of phenobarbital given to toxaemic and normal parturients on the serum bilirubin concentration of newborn infants.
Topics: Bilirubin; Enzyme Induction; Female; Fetus; Humans; Infant, Newborn; Liver; Maternal-Fetal Exchange; | 1970 |
17 other studies available for phenobarbital and Pre-Eclampsia
| Article | Year |
|---|---|
Maternal exposure to folic acid antagonists and placenta-mediated adverse pregnancy outcomes.
Topics: Abruptio Placentae; Adult; Cohort Studies; Female; Fetal Death; Fetal Growth Retardation; Folic Acid | 2008 |
METHYLDOPA IN TREATMENT OF SEVERE TOXAEMIA OF PREGNANCY.
Topics: Albuminuria; Antihypertensive Agents; Chlorothiazide; Female; Fetal Death; Humans; Methyldopa; Pheno | 1964 |
CONTROLLED TRIAL OF CHLOROTHIAZIDE IN TREATMENT OF EARLY PRE-ECLAMPSIA.
Topics: Albuminuria; Anemia; Chlorothiazide; Diet; Diet Therapy; Female; Humans; Outpatient Clinics, Hospita | 1964 |
TOXAEMIA OF PREGNANCY.
Topics: Albuminuria; Amobarbital; Blood Pressure; Edema; Female; Humans; Labor, Induced; Morphine; Paraldehy | 1964 |
AMAUROSIS IN PREGNANCY.
Topics: Acetazolamide; Amyl Nitrite; Blindness; Cesarean Section; Female; Ganglionic Blockers; Humans; Ophth | 1964 |
UTERINE HYPERCONTRACTILITY IN TOXEMIA OF PREGNANCY. I. ITS PROLONGED THERAPEUTIC CONTROL.
Topics: Amniotic Fluid; Diet, Sodium-Restricted; Diuretics; Drug Therapy; Eclampsia; Female; Humans; Hypnoti | 1964 |
[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)].
Topics: Acute Kidney Injury; Adolescent; Adult; Brain Edema; Critical Care; Diazepam; Dihydralazine; Eclamps | 1980 |
Antepartum fetal heart testing. III. The effect of phenobarbital on the nonstress test.
Topics: Female; Fetal Heart; Fetal Monitoring; Heart Rate; Humans; Phenobarbital; Pre-Eclampsia; Pregnancy | 1979 |
Maternal toxemia is associated with reduced incidence of germinal matrix hemorrhage in premature babies.
Topics: Cerebral Hemorrhage; Cerebral Palsy; Double-Blind Method; Female; Humans; Hypertension; Infant, Newb | 1992 |
Maternal and perinatal outcome of conservative management of severe preeclampsia in midtrimester.
Topics: Administration, Oral; Antihypertensive Agents; Bed Rest; Birth Weight; Delivery, Obstetric; Diuretic | 1985 |
Action of phenobarbitone in preeclampsia.
Topics: Female; Humans; Phenobarbital; Pre-Eclampsia; Pregnancy | 1969 |
Barbiturate and hyperbilirubinaemia of prematurity.
Topics: Barbiturates; Bilirubin; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Jaundice, Neo | 1969 |
Effect of phenobarbitone and pre-eclamptic toxaemia on neonatal jaundice.
Topics: Barbiturates; Female; Humans; Infant, Newborn; Jaundice, Neonatal; Maternal-Fetal Exchange; Phenobar | 1969 |
[Therapy of EPH gestosis].
Topics: Chlorthalidone; Diazepam; Diet Therapy; Eclampsia; Edema; Female; Furosemide; Guanethidine; Humans; | 1973 |
Neonatal withdrawal following maternal ingestion of ethchlorvynol (Placidyl).
Topics: Adult; Diagnosis, Differential; Ethchlorvynol; Female; Humans; Infant, Newborn; Infant, Newborn, Dis | 1973 |
Disappearance from the newborn of circulating prenatally administered phenobarbital.
Topics: Birth Weight; Female; Fetus; Gestational Age; Half-Life; Humans; Hypertension; Infant, Newborn; Kine | 1973 |
[Hospital management of pregnancy toxemias].
Topics: Diet Therapy; Female; Hospitalization; Humans; Infant, Newborn; Methods; Phenobarbital; Pre-Eclampsi | 1974 |