phenobarbital has been researched along with Polyploid in 9 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital was injected intraperitoneally into male white NMRI mice aged 0." | 5.26 | Excessive reversible phenobarbital induced nuclear DNA-polyploidization in the growing mouse liver. ( Böhm, N; Noltemeyer, N, 1981) |
| "Phenobarbital was injected intraperitoneally into male white NMRI mice aged 0." | 1.26 | Excessive reversible phenobarbital induced nuclear DNA-polyploidization in the growing mouse liver. ( Böhm, N; Noltemeyer, N, 1981) |
| "The phenobarbital-induced increase in the phospholipid and cytochrome P-450 content of the microsomes, as well as in the activities of microsomal reduced nicotinamide-adenine dinucleotide phosphate-cytochrome c reductase and N-demethylase, was correlated with the morphometric data on the endoplasmic reticulum." | 1.25 | Correlated morphometric and biochemical studies on the liver cell. II. Effects of phenobarbital on rat hepatocytes. ( Hess, R; Stäubli, W; Weibel, ER, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Böhm, N | 2 |
| Noltemeyer, N | 2 |
| Cascales, M | 1 |
| Alvarez, A | 1 |
| Gascó, P | 1 |
| Fernández-Simón, L | 1 |
| Sanz, N | 1 |
| Boscá, L | 1 |
| Martin, NC | 1 |
| McGregor, AH | 1 |
| Sansom, N | 1 |
| Gould, S | 1 |
| Harrison, DJ | 1 |
| Schulte-Hermann, R | 1 |
| Thom, R | 1 |
| Schlicht, I | 1 |
| Koransky, W | 1 |
| Stäubli, W | 1 |
| Hess, R | 1 |
| Weibel, ER | 1 |
| Foerst, D | 1 |
| Halbrecht, I | 1 |
| Komlos, L | 1 |
| Shabtay, F | 1 |
| Solomon, M | 1 |
| Böök, JA | 1 |
| Paulini, K | 1 |
| Beneke, G | 1 |
| Kulka, R | 1 |
9 other studies available for phenobarbital and Polyploid
| Article | Year |
|---|---|
Excessive reversible phenobarbital induced nuclear DNA-polyploidization in the growing mouse liver.
Topics: Aging; Animals; Cell Nucleus; DNA; Liver; Male; Mice; Phenobarbital; Polyploidy | 1981 |
Cocaine-induced liver injury in mice elicits specific changes in DNA ploidy and induces programmed death of hepatocytes.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Division; Cells, Cultured; Cocaine; Cytochrome P-45 | 1994 |
Phenobarbitone-induced ploidy changes in liver occur independently of p53.
Topics: Animals; Anticonvulsants; Cell Count; Cell Division; Cells, Cultured; Hepatocytes; Liver; Male; Mice | 2001 |
[Age-dependency of phenobarbital induced polyploidy formation of the hepatocytes in house mice].
Topics: Age Factors; Animals; Cell Division; Endoplasmic Reticulum; Liver; Male; Mice; Phenobarbital; Polypl | 1978 |
[Number and "ploidy" of liver cell nuclei under the influence of substances alien to the body. Analysis by means of an electronic particle counter].
Topics: Animals; Cell Nucleus; Electronics; Female; Hepatomegaly; Hexachlorocyclohexane; Hyperplasia; Hypert | 1968 |
Correlated morphometric and biochemical studies on the liver cell. II. Effects of phenobarbital on rat hepatocytes.
Topics: Animals; Cell Membrane; Cytochromes; Cytoplasm; Cytoplasmic Granules; Electron Transport Complex IV; | 1969 |
[Chromosome studies on the effect of primidone (Mylepsinum) and its metabolites phenobarbital and phenylethylmalondiamide in vitro].
Topics: Amides; Cell Division; Cells, Cultured; Chromosome Aberrations; Chromosomes; Humans; In Vitro Techni | 1972 |
Triploidy 69, XXX in a stillborn girl.
Topics: Adult; Asthma; Chromatids; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-1 | 1973 |
[Age dependency of phenobarbital induced liver enlargement. Cytophotometric and autoradiographic studies].
Topics: Age Factors; Animals; Autoradiography; Cell Nucleus; Densitometry; Diploidy; DNA; Hepatomegaly; Inje | 1971 |