Page last updated: 2024-11-02

phenobarbital and Poisoning

phenobarbital has been researched along with Poisoning in 107 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"Bromide toxicosis was diagnosed in an 8-year-old Labrador Retriever that had been treated for epilepsy with potassium bromide, at a dosage of 29 mg/kg of body weight/d."7.69Bromide toxicosis secondary to renal insufficiency in an epileptic dog. ( Linn, K; Nichols, ES; Trepanier, LA, 1996)
" Sorbitol, another osmotic cathartic commonly used in the treatment of drug intoxications, has been reported in the pediatric literature to induce severe hypernatremia, but there is only a rare case report in an adult."7.68Hypernatremia due to repeated doses of charcoal-sorbitol. ( Allerton, JP; Strom, JA, 1991)
" PROSPECTIVE CONTROLLED CLINICAL TRIALS: Two of the 94 publications were prospective controlled studies (only one stated that allocation was via blinded randomisation), and both assessed the effect of multiple-dose activated charcoal for acute phenobarbital poisoning."4.87Enhanced elimination in acute barbiturate poisoning - a systematic review. ( Buckley, NA; Roberts, DM, 2011)
"Bromide toxicosis was diagnosed in an 8-year-old Labrador Retriever that had been treated for epilepsy with potassium bromide, at a dosage of 29 mg/kg of body weight/d."3.69Bromide toxicosis secondary to renal insufficiency in an epileptic dog. ( Linn, K; Nichols, ES; Trepanier, LA, 1996)
" Sorbitol, another osmotic cathartic commonly used in the treatment of drug intoxications, has been reported in the pediatric literature to induce severe hypernatremia, but there is only a rare case report in an adult."3.68Hypernatremia due to repeated doses of charcoal-sorbitol. ( Allerton, JP; Strom, JA, 1991)
"Amoxapine is a second-generation antidepressant that has been reported to cause seizures, severe acidosis, cardiac dysrhythmias, hypotension, renal failure, coma, and cardiorespiratory arrest in poisoning exposures."3.68Diagnostic pitfalls associated with amoxapine overdose: a case report. ( Greenwood, RS; Hussey, B; Miles, MV, 1990)
"Assay of the clinical course of poisoning with acetic acid, dichloroethane, carbophos, chlorophos, phenobarbital and sodium etaminal in 2538 patients made it possible to define, with the use of the probit analysis, the 25, 50, 75 and 95% concentration thresholds of the lethality in acute poisonings with acetic acid, carbophos and dichloroethane."3.67[Age-related aspects of intensive therapy of acute poisoning of chemical etiology]. ( Dagaev, VN; Gorin, EE; Kostomarova, LG; Luzhnikov, EA, 1985)
" Further studies are required to establish its role and the optimal dosage regimen of charcoal to be administered."2.40Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. ( , 1999)
" At 42 h of age, the serum PB concentration was in the toxic range at 131 mg/L."1.48The Use of Peritoneal Dialysis in Phenobarbitone Toxicity in a Critically Unwell Neonate. ( Graudins, A; Johnstone, LM; Le Page, AK; Roehr, CC; Stewart, AE, 2018)
" In three healthy volunteers, 10 g of activated carbon beads administered orally 20 min after 120 mg of phenobarbital, reduced the total bioavailability by 57% (p less than 0."1.28Prevention of gastrointestinal absorption of phenobarbital by activated carbon beads as an oral adsorbent. ( Honda, Y; Nakano, M; Nakano, NI, 1990)
"Pretreatment with phenobarbital slowed the time course of acetylcholinesterase and hepatic aliesterase inhibition following parathion exposure, suggesting the induction of a detoxication pathway(s) to a greater extent than the induction of activation."1.28Time course of inhibition of acetylcholinesterase and aliesterases following parathion and paraoxon exposures in rats. ( Chambers, HW; Chambers, JE, 1990)
"This augmented necrosis is averted by prolonged treatment with hyperbaric oxygen."1.27Effect of hyperoxia on liver necrosis induced by hepatotoxins. ( Marzella, L; Muhvich, K; Myers, RA, 1986)
"Benign febrile convulsions occur early in the course of fever of extracranial origin in children six months to five years old."1.25Febrile seizures in children. ( Henderson, BM; Levi, JS, 1975)

Research

Studies (107)

TimeframeStudies, this research(%)All Research%
pre-199084 (78.50)18.7374
1990's13 (12.15)18.2507
2000's2 (1.87)29.6817
2010's8 (7.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mináriková, M1
Fojtikova, V1
Vyskočilová, E1
Sedláček, J1
Šikut, M1
Borek-Dohalska, L1
Stiborová, M1
Martinkova, M1
Bedet, A1
Alestra, A1
Vodovar, D1
Dessap, AM1
de Prost, N1
Le Page, AK1
Stewart, AE1
Roehr, CC1
Johnstone, LM1
Graudins, A1
Fenves, AZ1
Mojtahed, A1
Nisavic, M1
Massoth, LR1
de Bairros, AV1
Dias, D1
Bezerra, A1
Wagner, R1
Klein, B1
Kommers, G1
Stefanon, E1
Miguel Pego, A1
Roveri, FL1
Paranhos, BA1
Yonamine, M1
Desalew, M1
Aklilu, A1
Amanuel, A1
Addisu, M1
Ethiopia, T1
Roberts, DM1
Buckley, NA1
CURRY, AS1
CULLHED, I1
HIRAKI, K1
HYODO, K1
RAE, JL1
TRUSCOTT, MS1
UENO, Y1
MIURA, S1
TAKEMURA, N1
HASEGAWA, Y1
FROMMEL, E1
FLEURY, C1
LEDEBUR, IV1
BEGUIN, M1
FAMILY, S1
PLUMB, RL1
JOSEPH, SW1
HARVEY, NA1
WALLACE, HE1
NEUMAYER, F1
GUTCH, CF1
ZAVON, MR3
OSUNTOKUN, BO1
RIZZUTO, VJ1
INGLESBY, TV1
GRACE, WJ1
SCHAERER, K1
KOKENGE, R1
KUTT, H1
MCDOWELL, F1
MARCHAND, L1
TEULIE, G1
BALIER, C1
Kinoshita, H1
Nishiguchi, M1
Ouchi, H1
Minami, T1
Yamamura, T1
Yasui, T1
Marukawa, S1
Ameno, K1
Hishida, S1
van de Plas, A1
Stolk, L1
Verhoeven, MA1
Kooman, JP1
van Mook, WN1
Goulon, M1
Nouailhat, F1
Lévy-Alcover, MA1
Dordain, G1
Goulding, R2
Hildebrandt, J1
Lauschke, G1
Sinkwitz, KD1
Schmidt, J1
Pflüger, KH1
Tessore, V1
Luboz, MP1
Denti, E1
Raper, S1
Crome, P1
Vale, A1
Helliwell, M1
Widdop, B2
Levy, G1
Maliuk, VI1
Molotkov, VN1
Korzhov, VI1
De Wolff, FA1
Smit, ND1
Grünewald, EJ1
Schicht, IM1
Mantz, IM1
Kopferschitt, I1
Tempe, ID1
Jaeger, A1
Micheletti, G1
Coquillat, G1
Arbour, R1
Lin, JL2
Jeng, LB1
Lim, PS1
Söylemezoğlu, O1
Bakkaloğlu, A1
Yiğit, S1
Saatçi, U1
Nichols, ES1
Trepanier, LA1
Linn, K1
Sancak, R1
Küçüködük, S1
Taşdemir, HA1
Belet, N1
Plaa, GL1
Lightman, SL1
Koffler, A2
Bernstein, M1
LaSette, A1
Massry, SG1
Lesche, P1
Blume, U1
Scheibe, G1
Sussmann, P1
Schmidt, FW1
Bartels, M1
Okonek, S1
Rodríguez Olleros, A1
Dietrich, R1
Taveras, JE1
Hill, JB2
Palaia, FL2
McAdams, JL2
Palmer, PJ2
Skinner, JT1
Maret, SM2
Barbour, BH1
LaSette, AM1
Rosenbaum, JL1
Kramer, MS1
Raja, R1
Winsten, S1
Dalal, F1
Henderson, BM1
Levi, JS1
Bosl, R1
Shideman, JR1
Meyer, RM1
Buselmeier, TJ1
von Hartitzsch, B1
Kjellstrand, CM1
Harbison, RD1
Puka, J1
Szajewski, JM1
Haidvogl, M1
Rosegger, H1
Dinovo, EC1
Gottschalk, LA1
Kruse, JA1
Carlson, RW1
Allerton, JP1
Strom, JA1
Honda, Y1
Nakano, M1
Nakano, NI1
Bismuth, C1
Chambers, JE1
Chambers, HW1
Miles, MV1
Greenwood, RS1
Hussey, B1
Marzella, L1
Muhvich, K1
Myers, RA1
Opheim, KE1
Raisys, VA1
Porter, RS1
Baker, EB1
Luzhnikov, EA1
Dagaev, VN1
Kostomarova, LG1
Gorin, EE1
Mofenson, HC1
Caraccio, TR1
Greensher, J1
D'Agostino, R1
Rossi, A1
Shetty, SN1
Himes, JA1
Edds, GT1
von Baeyer, H1
Kunst, H1
Freiberg, J1
Grosser, KD1
Sieberth, HG1
Grabensee, B1
Lannek, B1
Yamada, S1
Iwai, K1
Fukase, M1
Yamada, T1
Ikeda, K1
Haider, I1
Oswald, I1
Atkinson, JP1
Azarnoff, DL1
Zavelson, TM1
Debusk, FL1
Blatman, S1
Bailey, DN1
Jatlow, PI1
Chédru, F1
Geschwind, N1
Silberman, A1
Yu, CT1
Lam, KW1
Grivaux, M1
Soulié, J1
Diallo, A1
Renard, C1
Chevalley, J1
Medd, RK1
Braithwaite, RA1
Rees, AJ1
Brillman, J1
Gallagher, BB1
Mattson, RH1
Kratz, F1
Gruska, H1
Barckow, D1
Heidrich, H1
Humpert, U1
Hüsten, J1
Ibe, K1
Weiss, D1
Selye, H1
Szabo, S1
Kourounakis, P1
Allen, JR1
Chesney, CF1
Frazee, WJ1
Fries, GF1
Marrow, GS1
Lester, JW1
Gordon, CH1
Cook, RM1
Wilson, KA1
Yatzidis, H1
Braund, DG1
Langlois, BE1
Conner, DJ1
Moore, EE1
Ikeda, M1
Otsuji, H1
Gifford, RR1
Brock, HT1
Dayton, PG1
Goldberg, LI1
Juul, S1
Sugerman, HJ1
Nealon, TF1
Raudonat, HW1
Staak, M1
Heyndrickx, A1
Van Hoof, F1
Okkerse, E1
Whang, R1
Orndorff, M1
Papper, S1
Marin, GA1
Montoya, CA1
Sierra, JL1
Senior, JR1
Iaroslavskiĭ, AA1
Firsov, NN1
Koldaev, AA1
Fiser, RH1
Maetz, HM1
Treuting, JJ1
Decker, WJ1
Sinnema, YA1
Landesman, LM1
Hart, LG1
Guarino, AM1
Schanker, LS1

Reviews

10 reviews available for phenobarbital and Poisoning

ArticleYear
Enhanced elimination in acute barbiturate poisoning - a systematic review.
    Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:1

    Topics: Acute Disease; Adult; Barbiturates; Clinical Trials as Topic; Female; Humans; Pentobarbital; Phenoba

2011
Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.
    Journal of toxicology. Clinical toxicology, 1999, Volume: 37, Issue:6

    Topics: Acute Disease; Animals; Carbamazepine; Cathartics; Charcoal; Dapsone; Drug Therapy, Combination; Hum

1999
Acute toxicity of antiepileptic drugs.
    Epilepsia, 1975, Volume: 16, Issue:1

    Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dogs;

1975
Fatal rodenticide poisoning with brodifacoum.
    Annals of emergency medicine, 1992, Volume: 21, Issue:3

    Topics: 4-Hydroxycoumarins; Adult; Blood Coagulation Disorders; Blood Transfusion; Drug Overdose; Emergency

1992
Therapeutic drug monitoring in pediatric acute drug intoxications.
    Therapeutic drug monitoring, 1985, Volume: 7, Issue:2

    Topics: Acetaminophen; Alcoholic Intoxication; Antidepressive Agents, Tricyclic; Child; Humans; Iron; Kineti

1985
Narcotic poisoning of children (1) through accidental ingestion of methadone and (2) in utero.
    Pediatrics, 1974, Volume: 54, Issue:3

    Topics: Administration, Oral; Apgar Score; Birth Weight; Child; Child Care; Female; Gestational Age; Heroin

1974
Poisoning from pesticides: diagnosis and treatment.
    Pediatrics, 1974, Volume: 54, Issue:3

    Topics: Antidotes; Arsenic Poisoning; Atropine; Carbamates; Child; Cholinesterase Inhibitors; Cholinesterase

1974
[On the problem of foreign substances detoxification through the liver].
    Deutsche medizinische Wochenschrift (1946), 1968, Dec-20, Volume: 93, Issue:51

    Topics: Benzopyrenes; Body Weight; Carbon Monoxide Poisoning; Coumarins; Endoplasmic Reticulum; Freeze Dryin

1968
Treatment of organophosphorus and chlorinated hydrocarbon insecticide intoxications.
    Modern treatment, 1971, Volume: 8, Issue:3

    Topics: Atropine; Cerebral Hemorrhage; Cholinesterase Inhibitors; Diagnosis, Differential; Gastroenteritis;

1971
[Therapy of acute poisoning].
    Medizinische Klinik, 1970, Apr-10, Volume: 65, Issue:15

    Topics: Antidotes; Diuresis; Gastric Lavage; Humans; Methods; Osmolar Concentration; Peritoneal Dialysis; Ph

1970

Trials

1 trial available for phenobarbital and Poisoning

ArticleYear
Evaluation of corticosteroid and exchange-transfusion treatment of acute yellow-phosphorus intoxication.
    The New England journal of medicine, 1971, Jan-21, Volume: 284, Issue:3

    Topics: Adolescent; Adult; Child; Exchange Transfusion, Whole Blood; Female; Glucocorticoids; Hepatic Enceph

1971

Other Studies

96 other studies available for phenobarbital and Poisoning

ArticleYear
The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study.
    Environmental toxicology and pharmacology, 2017, Volume: 52

    Topics: Adsorption; Alpha-Amanitin; Amlodipine; Antidotes; Aspirin; Carbamazepine; Charcoal; Digoxin; Ibupro

2017
Renal replacement therapy in severe phenobarbital poisoning: Another brick in the wall.
    Medicina intensiva, 2019, Volume: 43, Issue:7

    Topics: Antidotes; Charcoal; Female; Humans; Hypnotics and Sedatives; Middle Aged; Phenobarbital; Poisoning;

2019
The Use of Peritoneal Dialysis in Phenobarbitone Toxicity in a Critically Unwell Neonate.
    Neonatology, 2018, Volume: 113, Issue:2

    Topics: Anticonvulsants; Female; Humans; Infant; Infant, Newborn; Peritoneal Dialysis; Phenobarbital; Poison

2018
Case 13-2019: A 54-Year-Old Man with Alcohol Withdrawal and Altered Mental Status.
    The New England journal of medicine, 2019, Apr-25, Volume: 380, Issue:17

    Topics: 2-Propanol; Acetone; Acid-Base Equilibrium; Acidosis; Alcohol Withdrawal Delirium; Alcoholism; Diagn

2019
An analytical strategy for the identification of carbamates, toxic alkaloids, phenobarbital and warfarin in stomach contents from suspected poisoned animals by thin-layer chromatography/ultraviolet detection.
    Toxicology mechanisms and methods, 2019, Volume: 29, Issue:7

    Topics: Alkaloids; Animals; Carbamates; Cat Diseases; Cats; Chromatography, Thin Layer; Dog Diseases; Dogs;

2019
Determination of phenobarbital in hair matrix by liquid phase microextraction (LPME) and gas chromatography-mass spectrometry (GC-MS).
    Forensic science international, 2016, Volume: 265

    Topics: Forensic Pathology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Liquid Phase Microextraction

2016
Pattern of acute adult poisoning at Tikur Anbessa specialized teaching hospital, a retrospective study, Ethiopia.
    Human & experimental toxicology, 2011, Volume: 30, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Ethiopia; Female; Hospitals, Teaching; Household Products; Humans;

2011
A note on the paper chromatographic separation of phenobarbitone metabolites.
    The Journal of pharmacy and pharmacology, 1955, Volume: 7, Issue:9

    Topics: Barbiturates; Phenobarbital; Poisoning

1955
[A case of opium- and phenemal poisoning; case report].
    Svenska lakartidningen, 1955, Nov-18, Volume: 52, Issue:46

    Topics: Barbiturates; Humans; Opium; Phenobarbital; Poisoning

1955
[ON POISONING WITH ORGANIC CHLORINE AGRICULTURAL PREPARATIONS--BASIC AND CLINICAL ASPECTS OF THE -DRIN PREPARATIONS].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Chlorine; Dieldrin; Insecticides; Ions; Organic Agriculture; Pentobarbital; Phenobarbital; Physiolog

1964
REPORT OF A CASE OF STRYCHNINE POISONING TREATED BY INTERMITTENT POSITIVE-PRESSURE RESPIRATION AND RELAXANTS.
    The Medical journal of Australia, 1964, May-16, Volume: 1

    Topics: Gastric Lavage; Humans; Phenobarbital; Poisoning; Positive-Pressure Respiration; Strychnine; Suicide

1964
[CONVULSION CAUSED BY TELODRIN POISONING].
    No to shinkei = Brain and nerve, 1964, Volume: 16

    Topics: Drug Therapy; Electroencephalography; Insecticides; Phenobarbital; Poisoning; Seizures; Thioctic Aci

1964
THE PLACE OF ACETYLSALICYLIC ACID IN PSYCHOPHARMACOLOGY. AN EXPERIMENTAL STUDY.
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Amphetamine; Amphetamines; Animals; Aspirin; Body Temperature Regulation; Chlordiazepoxide; Chlorpro

1963
INGESTION OF A TOXIC OVERDOSE OF CHLORPROTHIXENE BY A 3 YEAR OLD.
    The Journal of pediatrics, 1964, Volume: 65

    Topics: Child; Chlorprothixene; Drug Therapy; Eating; Methylphenidate; Neurologic Manifestations; Phenobarbi

1964
ACCIDENTAL MULTIPLE DRUG POISONING.
    Pediatrics, 1964, Volume: 34

    Topics: Accidents; Appetite Depressants; Barbiturates; Child; Glucose; Infusions, Parenteral; Methamphetamin

1964
AMPHETAMINE POISONING AND PERITONEAL DIALYSIS. A CASE REPORT.
    American journal of diseases of children (1960), 1964, Volume: 108

    Topics: Blood Chemical Analysis; Body Fluids; Central Nervous System Agents; Dialysis; Fluid Therapy; Infant

1964
CHLORINATED HYDROCARBON INSECTICIDES. INTOXICATION AND GUIDE TO TREATMENT.
    JAMA, 1964, Nov-16, Volume: 190

    Topics: Antidotes; Calcium; Chlordan; DDT; Diagnosis; Dieldrin; Emetics; Gastric Lavage; Gluconates; Humans;

1964
"GAMMELIN 20" POISONING: A REPORT OF TWO CASES.
    The West African medical journal, 1964, Volume: 13

    Topics: Drug Therapy; Health Education; Hexachlorocyclohexane; Humans; Insecticides; Nigeria; Paraldehyde; P

1964
PROBENECID (BENEMID) INTOXICATION WITH STATUS EPILEPTICUS.
    The American journal of medicine, 1965, Volume: 38

    Topics: Coma; Drug Therapy; Epilepsy; Gout; Phenobarbital; Phenytoin; Poisoning; Probenecid; Status Epilepti

1965
[TOXICITY STUDIES WITH AMITRIPTYLINE. THERAPEUTIC GUIDE LINES FROM EXPERIMENTAL STUDIES].
    Schweizerische medizinische Wochenschrift, 1965, Jan-30, Volume: 95

    Topics: Amitriptyline; Chlordiazepoxide; Dogs; Electrocardiography; Mice; Parasympathomimetics; Pharmacology

1965
NEUROLOGICAL SEQUELAE FOLLOWING DILANTIN OVERDOSE IN A PATIENT AND IN EXPERIMENTAL ANIMALS.
    Neurology, 1965, Volume: 15

    Topics: Adolescent; Ataxia; Biomedical Research; Cats; Chlordiazepoxide; Drug Therapy; Epilepsy; Humans; Neu

1965
[Leukemia in an epileptic treated with gardenal and dihydan; recovery; fatal mysoline poisoning with fatty degeneration of the liver and acute epithelial nephritis].
    Annales medico-psychologiques, 1955, Volume: 113 1, Issue:2

    Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Hydantoins; Leukemia; Leukocytosis; Liver Diseases;

1955
Methanol: toxicity of the solvent in a commercial product should also be considered.
    Human & experimental toxicology, 2005, Volume: 24, Issue:12

    Topics: Aged; Drug Therapy, Combination; Fatal Outcome; Female; Formates; Humans; Hypnotics and Sedatives; I

2005
Successful treatment of acute phenobarbital intoxication by hemodiafiltration.
    Clinical toxicology (Philadelphia, Pa.), 2006, Volume: 44, Issue:1

    Topics: Female; Half-Life; Hemodiafiltration; Humans; Hypnotics and Sedatives; Middle Aged; Phenobarbital; P

2006
[Toxic coma with autonomic sideration, with a favorable outcome].
    Revue neurologique, 1967, Volume: 116, Issue:4

    Topics: Adult; Amobarbital; Body Temperature; Brain; Cardiovascular System; Chlorpromazine; Coma; Diazepam;

1967
The treatment of acute poisoning.
    Transactions of the Medical Society of London, 1967, Volume: 83

    Topics: Acute Disease; Antidotes; Atropine; Barbiturates; Carbon Monoxide Poisoning; Chlorpromazine; Deferox

1967
[Therapy of acute poisoning with orthograde intestinal lavage].
    Deutsche medizinische Wochenschrift (1946), 1983, Jun-24, Volume: 108, Issue:25

    Topics: Amitriptyline; Barbiturates; Diazepam; Dihydropyridines; Glyburide; Humans; Intestines; Mushroom Poi

1983
[Toxicology and therapy of paracetamol poisoning].
    Der Internist, 1980, Volume: 21, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Cysteamine; Drug Interactions; Ethanol; Gastric Lavage; Glutathione;

1980
Use of uncoated activated carbon hemoperfusion in acute poisoning: in vitro studies.
    Contributions to nephrology, 1982, Volume: 29

    Topics: Acute Disease; Adsorption; Animals; Blood Glucose; Blood Urea Nitrogen; Carbon; Creatinine; Hemoperf

1982
Experience with activated carbon-bead haemoperfusion columns in the treatment of severe drug intoxication. A preliminary report.
    Archives of toxicology, 1982, Volume: 49, Issue:3-4

    Topics: Acetaminophen; Adolescent; Adult; Aged; Charcoal; Female; Glutethimide; Hemoperfusion; Humans; Pheno

1982
Gastrointestinal clearance of drugs with activated charcoal.
    The New England journal of medicine, 1982, Sep-09, Volume: 307, Issue:11

    Topics: Adult; Charcoal; Child; Digestive System; Half-Life; Hemoperfusion; Humans; Intestinal Absorption; P

1982
[Metabolic disorders in acute poisoning and their correction by sodium succinate].
    Vrachebnoe delo, 1981, Issue:8

    Topics: Animals; Antitubercular Agents; Ethionamide; Guinea Pigs; Isoniazid; Phenobarbital; Poisoning; Rifam

1981
Evaluation of haemoperfusion by column analysis.
    Developments in toxicology and environmental science, 1980, Volume: 8

    Topics: Adult; Diuresis; Evaluation Studies as Topic; Hemoperfusion; Humans; Hypnotics and Sedatives; Kidney

1980
[The convulsive disease state. Apropos of 79 cases].
    Minerva medica, 1980, Oct-20, Volume: 71, Issue:40

    Topics: Adult; Aged; Anticonvulsants; Brain Diseases; Cerebrovascular Disorders; Electroencephalography; Epi

1980
Barbiturate overdose.
    Nursing, 1995, Volume: 25, Issue:1

    Topics: Adult; Emergency Nursing; Humans; Male; Nursing Assessment; Phenobarbital; Poisoning

1995
Critical, acutely poisoned patients treated with continuous arteriovenous hemoperfusion in the emergency department.
    Annals of emergency medicine, 1995, Volume: 25, Issue:1

    Topics: Acute Disease; Adult; Aged; Emergencies; Emergency Service, Hospital; Hemoperfusion; Humans; Male; M

1995
Continuous arteriovenous hemoperfusion in acute poisoning.
    Blood purification, 1994, Volume: 12, Issue:2

    Topics: Adult; Aged; Arteriovenous Shunt, Surgical; Coma; Fatal Outcome; Female; Hemodynamics; Hemoperfusion

1994
Haemodialysis treatment in phenobarbital intoxication in infancy.
    International urology and nephrology, 1993, Volume: 25, Issue:1

    Topics: Coma; Humans; Infant; Male; Phenobarbital; Poisoning; Renal Dialysis

1993
Bromide toxicosis secondary to renal insufficiency in an epileptic dog.
    Journal of the American Veterinary Medical Association, 1996, Jan-15, Volume: 208, Issue:2

    Topics: Animals; Anticonvulsants; Bromides; Creatinine; Diuresis; Dog Diseases; Dogs; Drug Therapy, Combinat

1996
Exchange transfusion treatment in a newborn with phenobarbital intoxication.
    Pediatric emergency care, 1999, Volume: 15, Issue:4

    Topics: Adult; Drug Overdose; Exchange Transfusion, Whole Blood; Female; Humans; Infant, Low Birth Weight; I

1999
Phenobarbital dyskinesia.
    Postgraduate medical journal, 1978, Volume: 54, Issue:628

    Topics: Adult; Chorea; Dyskinesia, Drug-Induced; Humans; Male; Phenobarbital; Poisoning

1978
Fixed-bed charcoal hemoperfusion. Treatment of drug overdose.
    Archives of internal medicine, 1978, Volume: 138, Issue:11

    Topics: Adolescent; Adult; Aged; Barbiturates; Calcium; Charcoal; Ethchlorvynol; Female; Glutethimide; Hemop

1978
[Hemoperfusion by means of encapsuled charcoal for the treatment of exogenous and endogenous intoxications].
    Klinische Wochenschrift, 1976, Jun-01, Volume: 54, Issue:11

    Topics: Adsorption; Bromides; Charcoal; Diazepam; Heparin; Hepatic Encephalopathy; Humans; Parathion; Perfus

1976
[Sensitivity of the antitoxic liver function. Experimental demonstration].
    Boletin de la Asociacion Medica de Puerto Rico, 1976, Volume: 68, Issue:7

    Topics: Acetamides; Animals; Dogs; Liver; Liver Function Tests; Pentobarbital; Phenobarbital; Poisoning; Thi

1976
The rationale for fixed-bed charcoal in hemoperfusion.
    Kidney international. Supplement, 1976, Issue:7

    Topics: Adsorption; Animals; Blood Platelets; Charcoal; Disease Models, Animal; Dogs; Filtration; Kidneys, A

1976
Fixed-bed charcoal hemoperfusion for the treatment of drug overdose.
    Kidney international. Supplement, 1976, Issue:7

    Topics: Adolescent; Adsorption; Adult; Blood Platelets; Charcoal; Chlordiazepoxide; Chlorpromazine; Ethchlor

1976
Hemoperfusion for acute drug intoxication.
    Kidney international. Supplement, 1976, Issue:7

    Topics: Adsorption; Adult; Ethchlorvynol; Glutethimide; Humans; Male; Methaqualone; Phenobarbital; Poisoning

1976
Febrile seizures in children.
    American family physician, 1975, Volume: 11, Issue:1

    Topics: Analgesics; Child, Preschool; Diagnosis, Differential; Dysentery, Bacillary; Electroencephalography;

1975
Effects and complications of high efficiency dialysis.
    Nephron, 1975, Volume: 15, Issue:2

    Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypote

1975
Parathion-induced toxicity and phenobarbital-induced protection against parathion during prenatal development.
    Toxicology and applied pharmacology, 1975, Volume: 32, Issue:3

    Topics: Animals; Body Weight; Cholinesterases; Female; Fetal Death; Fetus; Maternal-Fetal Exchange; Mice; Pa

1975
[Case of exceptionally severe luminal poisoning (over 25 g) successfully treated with hemodialysis and forced diuresis].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1975, Sep-22, Volume: 30, Issue:38

    Topics: Diuresis; Female; Furosemide; Humans; Phenobarbital; Poisoning; Renal Dialysis

1975
[Cyclizine-intoxication in six children (author's transl)].
    Padiatrie und Padologie, 1975, Volume: 10, Issue:2

    Topics: Adrenal Cortex Hormones; Age Factors; Ataxia; Chemical Phenomena; Chemistry; Child, Preschool; Cycli

1975
Letter: Non-accidental poisoning and child abuse.
    British medical journal, 1976, May-15, Volume: 1, Issue:6019

    Topics: Adolescent; Amitriptyline; Aspirin; Child; Child Abuse; Female; Humans; Infant; Infant, Newborn; Mal

1976
Efficacy of activated charcoal hemoperfusion in removing lethal doses of barbiturates and salicylate from the blood of rats and dogs.
    Clinical chemistry, 1976, Volume: 22, Issue:6

    Topics: Animals; Barbiturates; Charcoal; Disease Models, Animal; Dogs; Pentobarbital; Perfusion; Phenobarbit

1976
Results of a nine-laboratory survey of forensic toxicology proficiency.
    Clinical chemistry, 1976, Volume: 22, Issue:6

    Topics: Ethanol; Forensic Medicine; Glutethimide; Humans; Narcotics; Pentobarbital; Phenobarbital; Poisoning

1976
Hypernatremia due to repeated doses of charcoal-sorbitol.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 17, Issue:5

    Topics: Adult; Cathartics; Charcoal; Female; Humans; Hypernatremia; Phenobarbital; Poisoning; Sorbitol; Susp

1991
Prevention of gastrointestinal absorption of phenobarbital by activated carbon beads as an oral adsorbent.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:10

    Topics: Administration, Oral; Adsorption; Adult; Biological Availability; Carbon; Female; Humans; Intestinal

1990
Biological valuation of extra-corporeal techniques in acute poisoning.
    Acta clinica Belgica. Supplementum, 1990, Volume: 13

    Topics: Hemoperfusion; Humans; Inactivation, Metabolic; Intestinal Absorption; Liver; Meprobamate; Paraquat;

1990
Time course of inhibition of acetylcholinesterase and aliesterases following parathion and paraoxon exposures in rats.
    Toxicology and applied pharmacology, 1990, Volume: 103, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Brain; Carboxylesterase; Carboxylic Ester Hydrolases; C

1990
Diagnostic pitfalls associated with amoxapine overdose: a case report.
    The American journal of emergency medicine, 1990, Volume: 8, Issue:4

    Topics: Amoxapine; Child; Dibenzoxazepines; Electroencephalography; Emergencies; Female; Humans; Phenobarbit

1990
Effect of hyperoxia on liver necrosis induced by hepatotoxins.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1986, Volume: 51, Issue:6

    Topics: Acetaminophen; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cric

1986
Drug clearance by diarrhea induction.
    The American journal of emergency medicine, 1985, Volume: 3, Issue:3

    Topics: Animals; Diarrhea; Diffusion; Dogs; Electrolytes; Emergency Service, Hospital; Female; Male; Phenoba

1985
[Age-related aspects of intensive therapy of acute poisoning of chemical etiology].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:5

    Topics: Acetates; Acetic Acid; Acute Disease; Adult; Age Factors; Critical Care; Ethylene Dichlorides; Hemop

1985
Gastrointestinal dialysis with activated charcoal and cathartic in the treatment of adolescent intoxications.
    Clinical pediatrics, 1985, Volume: 24, Issue:12

    Topics: Adolescent; Adsorption; Adult; Aspirin; Cathartics; Charcoal; Female; Gastric Lavage; Half-Life; Hum

1985
Effect of phenobarbital on bishydroxycoumarin plasma concentrations and hypoprothrombinemic responses in sheep.
    American journal of veterinary research, 1972, Volume: 33, Issue:4

    Topics: Administration, Oral; Animals; Dicumarol; Drug Interactions; Female; Hypoprothrombinemias; Injection

1972
[Haemodialysis in intoxication with hypnotics (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Feb-01, Volume: 99, Issue:5

    Topics: Acute Kidney Injury; Adult; Barbiturates; Blood Pressure; Bromides; Diuresis; Diuretics; Electroence

1974
[Therapy of severe bromcarbamide poisoning].
    Deutsche medizinische Wochenschrift (1946), 1974, Nov-01, Volume: 99, Issue:44

    Topics: Blood Pressure Determination; Diuresis; Electroencephalography; Furosemide; Gastric Lavage; Germany,

1974
Toxicity of halogenated oxyquinolines in dogs. A clinical study. II. History, symptoms, laboratory findings, therapy, and follow-up.
    Acta veterinaria Scandinavica, 1974, Volume: 15, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dehydration; Dog Diseases; Dogs; Electrocardiograph

1974
[Proceedings: Urinary 6 beta-hydroxycortisol (6 beta-OH-F) level at the time of phenobarbital administration in patients with PCB poisoning].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: Adult; Aged; Female; Humans; Hydrocortisone; Male; Middle Aged; Phenobarbital; Poisoning; Polychlori

1974
Late brain recovery processes after drug overdose.
    British medical journal, 1970, May-09, Volume: 2, Issue:5705

    Topics: Adult; Benzazepines; Brain; Delirium; Drug Tolerance; Electroencephalography; Female; Humans; Hypnot

1970
Comparison of charcoal and attapulgite as gastrointestinal sequestrants in acute drug ingestions.
    Clinical toxicology, 1971, Volume: 4, Issue:1

    Topics: Adsorption; Aluminum; Aluminum Silicates; Animals; Charcoal; Dogs; Insecticides; Intestinal Absorpti

1971
Acute dextropropoxyphene hydrochloride (Darvon) poisoning.
    Pediatrics, 1973, Volume: 52, Issue:2

    Topics: Adolescent; Brain Damage, Chronic; Dextropropoxyphene; Diazepam; Female; Humans; Nalorphine; Phenoba

1973
Chemical analysis of massive crystalluria following primidone overdose.
    American journal of clinical pathology, 1972, Volume: 58, Issue:5

    Topics: Adult; Amides; Chromatography, Gas; Chromatography, Thin Layer; Crystallization; Female; Humans; Phe

1972
Disorders of higher cortical functions in acute confusional states.
    Cortex; a journal devoted to the study of the nervous system and behavior, 1972, Volume: 8, Issue:4

    Topics: Acute Disease; Adult; Affect; Anesthesia, General; Art; Attention; Cognition Disorders; Electronarco

1972
Antagonistic effect of pre-treatment with ATP on phenobarbital poisoning.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 5, Issue:3

    Topics: Adenosine Triphosphate; Animals; Male; Phenobarbital; Poisoning; Rats; Time Factors

1973
[Therapeutic hyperosmolarity].
    Annales de medecine interne, 1973, Volume: 124, Issue:3

    Topics: Adult; Bicarbonates; Blood Transfusion; Brain Diseases; Chemical and Drug Induced Liver Injury; Diaz

1973
Comparison of haemoperfusion and haemodialysis in the therapy of barbiturate intoxication in dogs.
    Archiv fur Toxikologie, 1973, Volume: 31, Issue:2

    Topics: Animals; Barbiturates; Blood Platelets; Dogs; Leukocytes; Pentobarbital; Perfusion; Phenobarbital; P

1973
Acute primidone intoxication.
    Archives of neurology, 1974, Volume: 30, Issue:3

    Topics: Amides; Biotransformation; Brain; Chromatography, Thin Layer; Crystallization; Electroencephalograph

1974
Effect of various steroids and nonsteroidal microsomal enzyme inducers upon propoxyphene intoxication.
    Neuroendocrinology, 1972, Volume: 9, Issue:5

    Topics: Animals; Dextropropoxyphene; Enzyme Induction; Estradiol; Female; Phenobarbital; Phenytoin; Poisonin

1972
Modifications of pyrrolizidine alkaloid intoxication resulting from altered hepatic microsomal enzymes.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Animals; Chloramphenicol; Dose-Response Relationship, Drug; Drug Interactions; Injections, Subcutane

1972
Effect of microsomal enzyme inducing drugs on DDt and dieldrin elimination from cows.
    Journal of dairy science, 1971, Volume: 54, Issue:3

    Topics: Animals; Cattle; Cattle Diseases; DDT; Dieldrin; Diet Therapy; Enzymes; Fats; Microsomes, Liver; Mil

1971
Removal of pesticide residues from dairy cattle.
    Journal of dairy science, 1971, Volume: 54, Issue:5

    Topics: Aluminum Silicates; Animals; Antidotes; Calcium; Carbon; Cattle; Cattle Diseases; DDT; Dieldrin; Fat

1971
Bullous lesions in acute barbiturate poisoning.
    JAMA, 1971, Jul-12, Volume: 217, Issue:2

    Topics: Acute Disease; Adult; Barbiturates; Blister; Conjunctiva; Humans; Male; Phenobarbital; Poisoning; Ti

1971
Feeding phenobarbital and activated carbon to accelerate dieldrin residue removal in a contaminated dairy herd.
    Journal of dairy science, 1971, Volume: 54, Issue:3

    Topics: Animals; Carbon; Cattle; Cattle Diseases; Dieldrin; Female; Food Additives; Milk; Phenobarbital; Poi

1971
Phenobarbital-induced protection against toxicity of toluene and benzene in the rat.
    Toxicology and applied pharmacology, 1971, Volume: 20, Issue:1

    Topics: Animals; Benzene; Benzoates; Chromatography, Paper; Chromatography, Thin Layer; Female; Glucuronates

1971
Increased clearances of phenobarbital and salicylate produced by dopamine in the dog.
    The American journal of the medical sciences, 1969, Volume: 258, Issue:5

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Dogs; Dopamine; Kidney; Phenobarbital; Poisoning; Sali

1969
[Barbiturate poisoning via breast milk?].
    Ugeskrift for laeger, 1969, Dec-18, Volume: 131, Issue:51

    Topics: Adult; Breast Feeding; Epilepsy; Female; Humans; Infant, Newborn; Milk, Human; Phenobarbital; Poison

1969
Effect of pH on phenobarbital extraction by hemoperfusion over anion exchange resins.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:1

    Topics: Animals; Dogs; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Exchange Resins; Male; P

1970
[Biochemical and medico-legal considerations of fatal megaphen (Chlorpromazine) poisoning in an infant. Problems in the separation of etiological relationships].
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1970, Volume: 67, Issue:2

    Topics: Child, Preschool; Chlorpromazine; Drug Synergism; Forensic Medicine; Humans; Phenobarbital; Poisonin

1970
The importance of gastric lavage in the treatment of poisoning.
    European journal of toxicology, 1970, Volume: 3, Issue:3

    Topics: Amobarbital; Barbiturates; Chloroform; Chromatography, Thin Layer; Forensic Medicine; Gastric Lavage

1970
Lipid-electrolyte ("lipo-lyte") dialysis--experimental and preliminary clinical observations.
    Clinical toxicology, 1970, Volume: 3, Issue:4

    Topics: Acid-Base Equilibrium; Adult; Animals; Cottonseed Oil; Dogs; Female; Humans; Lipids; Male; Methods;

1970
[Experimental determination of the effectiveness of hemodialysis of some medicinal substances and toxins].
    Biulleten' eksperimental'noi biologii i meditsiny, 1971, Volume: 71, Issue:4

    Topics: Alcoholic Intoxication; Amobarbital; Barbiturates; Ethanol; Humans; Methanol; Pentobarbital; Phenoba

1971
Activated charcoal in barbiturate and glutethimide poisoning of the dog.
    The Journal of pediatrics, 1971, Volume: 78, Issue:6

    Topics: Animals; Barbiturates; Charcoal; Dogs; Glutethimide; Intestinal Absorption; Phenobarbital; Poisoning

1971
The identification and determination of barbiturates in serum.
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1967, Volume: 5, Issue:1

    Topics: Barbiturates; Buffers; Chloroform; Diagnosis, Differential; Humans; Hydrogen-Ion Concentration; Phen

1967
[A case of severe acute poisoning by Bellaspon].
    Klinicheskaia meditsina, 1968, Volume: 46, Issue:11

    Topics: Adult; Atropa belladonna; Coma; Ergotamine; Female; Humans; Phenobarbital; Plants, Medicinal; Plants

1968
Gastric dialysis as a possible antidotal procedure for removal of absorbed drugs.
    The Journal of laboratory and clinical medicine, 1969, Volume: 73, Issue:5

    Topics: Aminopyrine; Aniline Compounds; Animals; Aspirin; Chlordiazepoxide; Gastric Lavage; Levorphanol; Mec

1969