Page last updated: 2024-11-02

phenobarbital and Plant Poisoning

phenobarbital has been researched along with Plant Poisoning in 5 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Plant Poisoning: Poisoning by the ingestion of plants or its leaves, berries, roots or stalks. The manifestations in both humans and animals vary in severity from mild to life threatening. In animals, especially domestic animals, it is usually the result of ingesting moldy or fermented forage.

Research Excerpts

ExcerptRelevanceReference
" Induction by phenobarbitone provided a degree of protection against the toxic effects of B."1.31Effect of phenobarbitone treatment against signal grass (Brachiaria decumbens) toxicity in sheep. ( Abdullah, AS; Elsheikh, HA; Hasiah, AH; Khairi, HM; Rajion, MA, 2000)
" There was no difference in NADPH-cytochrome c reductase or 7-ethoxyresorufin-O-deethylase (EROD) activity between ewes, control lambs and phenobarbitone-dosed lambs 3 weeks after dosing ceased."1.28Microsomal enzymes in lambs and adult sheep, and their possible relationship to alveld. ( Flåøyen, A; Jensen, EG, 1991)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kees, M1
Beckel, N1
Sharp, C1
Hasiah, AH1
Elsheikh, HA1
Abdullah, AS1
Khairi, HM1
Rajion, MA1
Flåøyen, A1
Jensen, EG1
Allen, JG1
Seawright, AA1
Gallagher, CH1
Koch, JH1
Hoffman, H1

Other Studies

5 other studies available for phenobarbital and Plant Poisoning

ArticleYear
Successful treatment of Solanum dulcamara intoxication in a Labrador retriever puppy.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2015, Volume: 56, Issue:12

    Topics: Animals; Dog Diseases; Dogs; Hypnotics and Sedatives; Male; Methocarbamol; Muscle Relaxants, Central

2015
Effect of phenobarbitone treatment against signal grass (Brachiaria decumbens) toxicity in sheep.
    Veterinary journal (London, England : 1997), 2000, Volume: 160, Issue:3

    Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cytochrome P-450 Enzyme System; Enzyme Indu

2000
Microsomal enzymes in lambs and adult sheep, and their possible relationship to alveld.
    Veterinary research communications, 1991, Volume: 15, Issue:4

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Disease Susceptibility; Female; Gl

1991
The effect of prior treatment with phenobarbitone, dicophane (DDT) and beta-diethylaminoethyl phenylpropyl acetate (SKF 525A) on experimental intoxication of sheep with the plant Myoporum deserti Cunn.
    Research in veterinary science, 1973, Volume: 15, Issue:2

    Topics: Animals; Bilirubin; Biopsy; DDT; Edema; Eosinophils; Gallbladder; Gastrointestinal Hemorrhage; Ische

1973
Electro-myographic studies on sheep injected with the N,N-dimethylated tryptamine alkaloids of Phalaris tuberosa.
    International journal of neuropharmacology, 1967, Volume: 6, Issue:3

    Topics: Alkaloids; Animals; Barbiturates; Cordotomy; Electric Stimulation; Electromyography; Injections, Int

1967