phenobarbital has been researched along with Peripheral Nervous System Diseases in 14 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute intermittent porphyria (AIP) is a rare metabolic disorder of heme biosynthesis characterized by enzymatic defect of porphobiligen desaminase with accumulation and increased excretion of porphyrins and their precursors." | 7.75 | [Neurological complications of acute intermittent porphyria precipitated by porphyrinogenic drugs and efficiency of heme-arginate treatment]. ( Akopova-Larbi, R; Ben Youssef, TI; Gargouri, A; Gouider, R; Gouider-Khouja, N; Kraoua, I, 2009) |
| "Acute intermittent porphyria (AIP) is a rare metabolic disorder of heme biosynthesis characterized by enzymatic defect of porphobiligen desaminase with accumulation and increased excretion of porphyrins and their precursors." | 3.75 | [Neurological complications of acute intermittent porphyria precipitated by porphyrinogenic drugs and efficiency of heme-arginate treatment]. ( Akopova-Larbi, R; Ben Youssef, TI; Gargouri, A; Gouider, R; Gouider-Khouja, N; Kraoua, I, 2009) |
| " We consider his cerebellar symptoms and peripheral neuropathy could be attributable to the long-term use of multiple anticonvulsants, i." | 1.29 | [Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy]. ( Kubota, M; Nagata, J, 1993) |
| " We found a noticeable relationship between conduction velocity slowing and daily dosage for CBZ only." | 1.27 | Anticonvulsant therapy and its possible consequences on peripheral nervous system: a neurographic study. ( Faedda, MT; Geraldini, C; Sideri, G, 1984) |
| "During this treatment a severe mainly motor polyneuropathy occurred acutely which was more pronounced in the distal parts of the legs, and cerebellar symptoms were noted at the same time." | 1.25 | [Acute polyneuropathy caused by diphenylhydantoin intoxication (author's transl)]. ( Bajc, O; Meienberg, O, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (78.57) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Akopova-Larbi, R | 1 |
| Ben Youssef, TI | 1 |
| Gargouri, A | 1 |
| Kraoua, I | 1 |
| Gouider, R | 1 |
| Gouider-Khouja, N | 1 |
| Geraldini, C | 1 |
| Faedda, MT | 1 |
| Sideri, G | 1 |
| Swift, TR | 1 |
| Gross, JA | 1 |
| Ward, LC | 1 |
| Crout, BO | 1 |
| Shorvon, SD | 1 |
| Reynolds, EH | 2 |
| Kubota, M | 1 |
| Nagata, J | 1 |
| Edwards, PM | 1 |
| Meienberg, O | 1 |
| Bajc, O | 1 |
| Abdel-Rahman, MS | 1 |
| Hetland, LB | 1 |
| Couri, D | 1 |
| Boldyrev, AI | 1 |
| Fleĭs, EP | 1 |
| Vaĭntrub, MIa | 1 |
| Baldini, S | 1 |
| Carenini, L | 1 |
| Leone, M | 1 |
| D'Alessandro, G | 1 |
| Bottacchi, E | 1 |
| Greenberg, JO | 1 |
| Eisen, AA | 1 |
| Woods, JF | 1 |
| Sherwin, AL | 1 |
| Encinoza, O | 1 |
14 other studies available for phenobarbital and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
[Neurological complications of acute intermittent porphyria precipitated by porphyrinogenic drugs and efficiency of heme-arginate treatment].
Topics: Acute Disease; Adolescent; Arginine; Electromyography; Famotidine; Female; Heme; Heme Oxygenase (Dec | 2009 |
Anticonvulsant therapy and its possible consequences on peripheral nervous system: a neurographic study.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neural Conduction; Peripheral Nerves; Peripheral N | 1984 |
Peripheral neuropathy in epileptic patients.
Topics: Epilepsy; H-Reflex; Humans; Neural Conduction; Peripheral Nervous System Diseases; Peroneal Nerve; P | 1981 |
Anticonvulsant peripheral neuropathy: a clinical and electrophysiological study of patients on single drug treatment with phenytoin, carbamazepine or barbiturates.
Topics: Adolescent; Adult; Aged; Barbiturates; Carbamazepine; Evoked Potentials, Somatosensory; Humans; Medi | 1982 |
[Lennox syndrome associated with severe cerebellar dysfunction and peripheral neuropathy].
Topics: Adult; Anticonvulsants; Brain; Cerebellar Ataxia; Drug Therapy, Combination; Epilepsy, Generalized; | 1993 |
Neurotoxicity of acrylamide and its analogues and effects of these analogues and other agents on acrylamide neuropathy.
Topics: Acrylamides; Animals; Ataxia; Brachial Plexus; Chickens; DDT; Female; Goldfish; Male; Nerve Degenera | 1975 |
[Acute polyneuropathy caused by diphenylhydantoin intoxication (author's transl)].
Topics: Acute Disease; Adult; Cerebellar Diseases; Epilepsy, Tonic-Clonic; Humans; Male; Peripheral Nervous | 1975 |
Toxicity and metabolism of methyl n-butyl ketone.
Topics: Animals; Atmosphere Exposure Chambers; Butanones; Chromatography, Gas; Environmental Exposure; Feces | 1976 |
[Neurologic complications following medical treatment of epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Ataxia; Benzodiazepines; Consciousness Disorders; Dysarthria; Ey | 1979 |
Peripheral neuropathy caused by antiepileptic drugs. Neurophysiological study of the A delta and C fibers.
Topics: Adolescent; Adult; Aged; Carbamazepine; Cold Temperature; Hot Temperature; Humans; Middle Aged; Nerv | 1992 |
The neurological effects of methyl bromide poisoning.
Topics: Adult; Amobarbital; Brain Diseases; Bromine; Cerebellar Ataxia; Diazepam; Dimercaprol; Electroenceph | 1971 |
Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation.
Topics: Adult; Aged; Carbamazepine; Electric Stimulation; Electromyography; Epilepsy; Ethosuximide; Evoked P | 1974 |
Nerve conduction velocity in patients on long-term diphenylhydantoin therapy.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Drug Therapy, Combination; Electrodiagnosis; Epilepsy; | 1974 |
Iatrogenic disorders in epilepsy.
Topics: Adrenal Insufficiency; Anemia, Macrocytic; Animals; Anticonvulsants; Cats; Cerebellar Diseases; Drug | 1970 |