phenobarbital has been researched along with Paralysis in 39 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The data obtained show that phenobarbital and chlordane decrease zoxazolamine paralysis time and increase liver weight and biliary flow." | 3.67 | Effects of phenobarbital, chlordane, and oxytetracycline on DDT excretion in rats. ( Doki, M; Puga, FR; Rodrigues, MA, 1986) |
| "The effects of modifiers of the microsomal mixed-function oxidase system on acrylamide-induced hind-limb paralysis were investigated in rats." | 3.67 | Effects of mixed-function oxidase modifiers on neurotoxicity of acrylamide in rats. ( Das, M; Mukhtar, H; Seth, PK; Srivastava, SP, 1985) |
| "Zoxazolamine paralysis, hexobarbital anesthesia and digitoxin convulsions were diminished in rats by 3 days of pretreatment with pregnenolone-16alpha-carbonitrile (PCN)." | 3.65 | Studies on drug metabolism and liver ultrastructure after conjoint treatment with pregnenolone-16alpha-carbonitrile and dl-ethionine. ( Garg, BD; Kourounakis, P; Kovacs, K; Szabo, S; Tuchweber, B, 1977) |
| "These were presence of seizures, grading of encephalopathy and neurobehavioural assessment at discharge from the hospital." | 1.30 | Clinical predictors of outcome in hypoxic ischaemic encephalopathy in term neonates. ( Aggarwal, P; Barve, S; Bhave, S; Chaudhari, S; Pandit, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (94.87) | 18.7374 |
| 1990's | 2 (5.13) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| OKUDA, O | 1 |
| SHINOHARA, S | 1 |
| WAITZOVA, D | 1 |
| SOBEK, V | 1 |
| HAVA, M | 1 |
| KARGEROVA, A | 1 |
| Lenn, NJ | 1 |
| Hamill, JS | 1 |
| Short, RD | 1 |
| Lee, CC | 1 |
| Monnet, FP | 1 |
| Debonnel, G | 1 |
| de Montigny, C | 1 |
| Aggarwal, P | 1 |
| Chaudhari, S | 1 |
| Bhave, S | 1 |
| Pandit, A | 1 |
| Barve, S | 1 |
| Frontali, N | 1 |
| Guarcini, AM | 1 |
| Spagnolo, A | 1 |
| Amantini, MC | 1 |
| Chow, CP | 1 |
| Cornish, HH | 1 |
| Botez, MI | 1 |
| Peyronnard, JM | 1 |
| Bérubé, L | 1 |
| Labrecque, R | 1 |
| Unseld, A | 1 |
| de Matteis, F | 1 |
| Garg, BD | 2 |
| Kourounakis, P | 1 |
| Tuchweber, B | 2 |
| Szabo, S | 2 |
| Kovacs, K | 1 |
| Mathur, PP | 1 |
| Smyth, RD | 1 |
| Witmer, CM | 1 |
| Carr, GS | 1 |
| Reavey-Cantwell, NH | 1 |
| Wiebel, FJ | 1 |
| Waters, HL | 1 |
| Elliot, S | 1 |
| Gelboin, HV | 1 |
| Salas, M | 1 |
| Puga, FR | 1 |
| Rodrigues, MA | 1 |
| Doki, M | 1 |
| Srivastava, SP | 1 |
| Seth, PK | 1 |
| Das, M | 1 |
| Mukhtar, H | 1 |
| Selye, H | 1 |
| Mécs, I | 1 |
| Marsden, CD | 1 |
| Reynolds, EH | 1 |
| Parsons, V | 1 |
| Harris, R | 1 |
| Duchen, L | 1 |
| Arseni, C | 1 |
| Marinescu, V | 1 |
| Kramer, S | 1 |
| Viljoen, D | 1 |
| Becker, D | 1 |
| Metz, J | 1 |
| Kato, R | 3 |
| Takanaka, A | 3 |
| Klaassen, CD | 1 |
| Freund, G | 1 |
| Murphy, JP | 1 |
| Van Stee, EW | 1 |
| Back, KC | 1 |
| Haase, J | 1 |
| Jepsen, BV | 1 |
| Bech, H | 1 |
| Langeback, E | 1 |
| Yamamoto, K | 1 |
| Sawada, T | 1 |
| Naito, Y | 1 |
| Kido, R | 1 |
| Buu-Hoï, NP | 1 |
| Hien, DP | 1 |
| Saint-Ruf, G | 1 |
| Servoin-Sidoine, J | 1 |
| Stenger, RJ | 2 |
| Johnson, EA | 2 |
| Chen, FC | 1 |
| Cavanagh, JB | 1 |
| Brodeur, J | 1 |
| Marchand, C | 1 |
| Abernathy, CO | 1 |
| Philpot, RM | 1 |
| Guthrie, FE | 1 |
| Hodgson, E | 1 |
| Breckenridge, A | 2 |
| Orme, M | 1 |
| Oshima, T | 1 |
| Kretzschmar, R | 2 |
| Meyer, HJ | 2 |
| Teschendorf, HJ | 2 |
| Zöllner, B | 1 |
| Davies, DS | 1 |
| Orme, ML | 1 |
| Thorgeirsson, S | 1 |
| Straw, RN | 1 |
| Mitchell, CL | 1 |
1 review available for phenobarbital and Paralysis
| Article | Year |
|---|---|
[Substances capable of inducing polyneuropathies, used in the shoe industry (triarylphosphates, aliphatic hydrocarbons, C5-C7)].
Topics: Acetylcholinesterase; Air Pollutants; Air Pollutants, Occupational; Alkanes; Animals; Birds; Butyryl | 1979 |
38 other studies available for phenobarbital and Paralysis
| Article | Year |
|---|---|
[OBSERVATION ON TWO CASES OF EPILEPSIA CURSIVA].
Topics: Adolescent; Atrophy; Barbiturates; Cerebral Cortex; Chlordiazepoxide; Dichlorphenamide; Electroencep | 1964 |
STUDIES ON DETOXIFICATION OF NEOMYCIN.
Topics: Calcium Chloride; Central Nervous System; Cerebral Ventricles; Chlorides; Desoxycorticosterone; Dihy | 1965 |
Congenital radial nerve pressure palsy.
Topics: Female; Humans; Infant, Newborn; Male; Nerve Compression Syndromes; Paralysis; Phenobarbital; Pregna | 1983 |
Effect of some nitrotoluenes on the biotransformation of xenobiotics in rats.
Topics: Animals; Biotransformation; Dinitrobenzenes; Male; Nitrobenzenes; Paralysis; Phenobarbital; Rats; Sl | 1980 |
The cytochromes P-450 are not involved in the modulation of the N-methyl-D-aspartate response by sigma ligands in the rat CA3 dorsal hippocampus.
Topics: Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophysiology; Guanid | 1993 |
Clinical predictors of outcome in hypoxic ischaemic encephalopathy in term neonates.
Topics: Anticonvulsants; Apgar Score; Asphyxia Neonatorum; Cerebral Palsy; Cerebrovascular Disorders; Female | 1998 |
Effects of lead on the induction of hepatic microsomal enzymes by phenobarbital and 3,4-benzpyrene.
Topics: Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Drug Interactions; Enz | 1978 |
Relapsing neuropathy, cerebral atrophy and folate deficiency. A close association.
Topics: Atrophy; Brain Diseases; Edema; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intesti | 1979 |
Destruction of endogenous and exogenous haem by 2-allyl-2-isopropylacetamide: role of the liver cytochrome P-450 which is inducible by phenobarbitone.
Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; E | 1978 |
Studies on drug metabolism and liver ultrastructure after conjoint treatment with pregnenolone-16alpha-carbonitrile and dl-ethionine.
Topics: Animals; Digitoxin; Drug Interactions; Ethionine; Female; Hexobarbital; In Vitro Techniques; Liver; | 1977 |
Temporal pattern and reversal of impaired hepatic mono-oxygenases by phenobarbital in rats with developing and established adjuvant disease.
Topics: Animals; Arthritis; Arthritis, Experimental; Cytochromes; Hexobarbital; Male; Microsomes, Liver; Oxy | 1977 |
Effect of 7 8-benzoflavone on the duration of zoxazolamine paralysis and hexobarbital hypnosis in rats.
Topics: Animals; Depression, Chemical; Flavonoids; Hexobarbital; Male; Methylcholanthrene; Paralysis; Phenob | 1976 |
Microsomal enzyme inducers and hypervitaminosis A in rats.
Topics: Animals; Bone Diseases; Enzyme Induction; Female; Liver; Microsomes, Liver; Paralysis; Phenobarbital | 1976 |
Effects of phenobarbital, chlordane, and oxytetracycline on DDT excretion in rats.
Topics: Animals; Bile; Chlordan; DDT; Male; Oxytetracycline; Paralysis; Phenobarbital; Rats; Rats, Inbred St | 1986 |
Effects of mixed-function oxidase modifiers on neurotoxicity of acrylamide in rats.
Topics: Acrylamide; Acrylamides; Animals; Cobalt; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Mal | 1985 |
Protection by catatoxic steroids against the paralysis caused by combined treatment with thyroxine and methylphenidate.
Topics: Androstenols; Animals; Drug Synergism; Estradiol; Ethylestrenol; Female; Humans; Hydroxysteroids; Hy | 1972 |
Myopathy associated with anticonvulsant osteomalacia.
Topics: Adult; Anticonvulsants; Back Pain; Depression; Electroencephalography; Electromyography; Ergocalcife | 1973 |
Epilepsy in cerebral hydatidosis.
Topics: Adolescent; Adult; Brain Diseases; Child; Child, Preschool; Dominance, Cerebral; Echinococcosis; Ele | 1974 |
A possible explanation for the neurological disturbances in the porphyrias.
Topics: Adenosine Triphosphatases; Amino Acids; Animals; Brain; Cystine; Erythrocytes; Glycine; Humans; Levu | 1971 |
Effect of starvation on the in vivo metabolism and effect of drugs in female and male rats.
Topics: Amides; Anesthesia; Animals; Barbiturates; Body Weight; Carisoprodol; Diphosphates; Female; Hexobarb | 1967 |
Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides.
Topics: Analysis of Variance; Animals; Bile; Biotransformation; Cardiac Glycosides; Digitoxin; Digoxin; Dose | 1974 |
Alcohol, barbiturate, and bromide withdrawal syndromes in mice.
Topics: Alcohol Drinking; Alcoholism; Animals; Barbiturates; Body Weight; Bromides; Diet; Disease Models, An | 1973 |
Effect of dibromotetrafluoroethane inhalation on hepatic drug metabolism in mice.
Topics: Animals; Chlorofluorocarbons, Methane; Drug Interactions; Hexobarbital; Hydrocarbons, Halogenated; L | 1973 |
Spinal fracture following radiculography using meglumine iothalamate (Conray).
Topics: Adipates; Adult; Contrast Media; Diazepam; Female; Fractures, Bone; Humans; Hypesthesia; Iothalamic | 1973 |
[Neuropharmacologic study on the effect of nitrazepam on the central nervous system].
Topics: Aggression; Amygdala; Animals; Appetitive Behavior; Behavior, Animal; Benzazepines; Brain; Cats; Cer | 1969 |
[Canceromimetic properties of the tetrachloro-2,3,7,8 dibenzo-p-dioxin ("dioxin")].
Topics: Animals; Arginase; Carcinogens; Dioxins; Enzyme Induction; Glycolates; Liver; Liver Neoplasms; Male; | 1971 |
Modifying effect of 3-amino-1,2,4-triazole on phenobarbital-induced changes in rat liver.
Topics: Amitrole; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochrom | 1972 |
Effects of phenobarbital pretreatment on the response of rat liver to halothane administration.
Topics: Anesthesia, General; Animals; Chemical and Drug Induced Liver Injury; Cytochromes; Enzyme Induction; | 1972 |
Factors affecting neurotoxicity by p-bromophenylacetylurea in rats.
Topics: Acetylcholinesterase; Age Factors; Animals; Biotransformation; Carbon Tetrachloride Poisoning; Chemi | 1971 |
Effect of splenectomy on the activity of drug-metabolizing enzymes in the liver of rats.
Topics: Animals; Anisoles; Biological Assay; Carbon Isotopes; Cytochromes; Enzyme Induction; Female; Hexobar | 1971 |
Inductive effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane(DDT), phenobarbital, and benzpyrene on microsomal cytochrome B450, ethyl isocyanide spectra, and metabolism in vivo of zoxazolamine and hexobarbital in the mouse.
Topics: Animals; Benzopyrenes; Cyanides; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Hexobarbital | 1971 |
Clinical implications of enzyme induction.
Topics: Alcohols; Amobarbital; Animals; Antipyrine; Benzazepines; Blood Coagulation; Chloral Hydrate; Chlord | 1971 |
Drug metabolism in tumor-bearing rats. II. In vivo metabolisms and effects of drugs in tumor-bearing rats.
Topics: Anesthesia; Animals; Carcinoma 256, Walker; Carisoprodol; Cholinesterase Inhibitors; Female; Injecti | 1968 |
Metabolism of drugs in old rats. II. Metabolism in vivo and effect of drugs in old rats.
Topics: Aging; Anesthesia; Animals; Carisoprodol; Female; Hexobarbital; Injections, Intraperitoneal; Insecti | 1968 |
[Antagonistic action of natural 5,6-hydrogenated Kava pyrones against strychnine poisoning and experimental local tetanus].
Topics: Anesthetics; Animals; Antidotes; Ataxia; Electromyography; Isonicotinic Acids; Male; Mephenesin; Mic | 1969 |
Strychnine antagonistic potency of pyrone compounds of the kavaroot (Piper methysticum Forst.).
Topics: Animals; Mephenesin; Mice; Paralysis; Phenobarbital; Plants, Medicinal; Pyrans; Reflex; Seizures; St | 1970 |
Screening methods for measuring liver microsomal enzyme induction by drugs.
Topics: Animals; Carbon Isotopes; Enzyme Induction; Liver; Male; Microsomes; Paralysis; Phenobarbital; Rats; | 1969 |
Effect of phenobarbital on cortical after-discharge and overt seizure patterns in the cat.
Topics: Animals; Cats; Cerebral Cortex; Cortical Spreading Depression; Electroencephalography; Electrophysio | 1966 |