phenobarbital has been researched along with Papilloma in 7 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Papilloma: A circumscribed benign epithelial tumor projecting from the surrounding surface; more precisely, a benign epithelial neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic cells. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two-stage carcinogenesis of mouse skin papillomas induced by 7,12-dimethylbenz[alpha]anthracene and 12-O-tetradecanoylphorbol 13-acetate, and mouse hepatic tumors induced by N-nitrosodiethylamine and phenobarbital, were inhibited by lantadenes." | 3.69 | Anti-tumor promoting activities of lantadenes on mouse skin tumors and mouse hepatic tumors. ( Inada, A; Nakanishi, T; Nishino, H; Sharma, OP; Tokuda, H, 1997) |
| " Dose-response studies of the capacity of 7,8-BF to inhibit DMBA tumor initiation revealed that 7,8-BF was an effective inhibitor at 2." | 1.26 | The effects of benzoflavones on polycyclic hydrocarbon metabolism and skin tumor initiation. ( Berry, DL; Digiovanni, J; Juchau, MR; Slaga, TJ; Thompson, S; Viaje, A, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsuda, H | 1 |
| Fukushima, S | 1 |
| Imaida, K | 1 |
| Kurata, Y | 1 |
| Ito, N | 1 |
| Inada, A | 1 |
| Nakanishi, T | 1 |
| Tokuda, H | 2 |
| Nishino, H | 2 |
| Sharma, OP | 1 |
| Konoshima, T | 1 |
| Takasaki, M | 1 |
| Ichiishi, E | 1 |
| Murakami, T | 1 |
| Duc, NM | 1 |
| Kasai, R | 1 |
| Yamasaki, K | 1 |
| Wislocki, PG | 1 |
| Miller, EC | 1 |
| Miller, JA | 1 |
| McCoy, EC | 1 |
| Rosenkranz, HS | 1 |
| Slaga, TJ | 1 |
| Thompson, S | 1 |
| Berry, DL | 1 |
| Digiovanni, J | 1 |
| Juchau, MR | 1 |
| Viaje, A | 1 |
| Grube, DD | 1 |
| Peraino, C | 1 |
| Fry, RJ | 1 |
| Diwan, BA | 1 |
| Hagiwara, A | 1 |
| Ward, JM | 1 |
| Rice, JM | 1 |
7 other studies available for phenobarbital and Papilloma
| Article | Year |
|---|---|
Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea.
Topics: Adenocarcinoma, Papillary; Animals; Cocarcinogenesis; Liver Neoplasms; Male; Methylnitrosourea; Nitr | 1983 |
Anti-tumor promoting activities of lantadenes on mouse skin tumors and mouse hepatic tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Diethylnitrosamine; | 1997 |
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.
Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Diethylnitr | 1999 |
Carcinogenic and mutagenic activities of safrole, 1'-hydroxysafrole, and some known or possible metabolites.
Topics: Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Dioxoles; Female; Liver; Liver Ne | 1977 |
The effects of benzoflavones on polycyclic hydrocarbon metabolism and skin tumor initiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzopyrene Hydroxylase; Carcinoma; D | 1977 |
The effect ofdietary phenobarbital on the induction of skin tumors in hairless mice with 7, 12-dimethylbenz(a)anthracene.
Topics: Administration, Oral; Animal Feed; Animals; Benz(a)Anthracenes; Diet; Dose-Response Relationship, Dr | 1975 |
Effects of sodium salts of phenobarbital and barbital on development of bladder tumors in male F344/NCr rats pretreated with either N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide or N-nitrosobutyl-4-hydroxybutylamine.
Topics: Animals; Barbital; Barbiturates; Butylhydroxybutylnitrosamine; Carcinoma; Cocarcinogenesis; FANFT; M | 1989 |