phenobarbital has been researched along with Pancytopenia in 3 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Bernard-mastiff crossbred dog showed clinical signs of lethargy and anorexia after being administered phenobarbital for the treatment of idiosyncratic seizures." | 8.02 | Pancytopenia secondary to suspected idiosyncratic phenobarbital reaction in a dog. ( Oberholster, O, 2021) |
| " Bernard-mastiff crossbred dog showed clinical signs of lethargy and anorexia after being administered phenobarbital for the treatment of idiosyncratic seizures." | 4.02 | Pancytopenia secondary to suspected idiosyncratic phenobarbital reaction in a dog. ( Oberholster, O, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Oberholster, O | 1 |
| Wolski, TP | 1 |
| Blasick, S | 1 |
| Blackford, MG | 1 |
| John, K | 1 |
| Hermann, J | 1 |
| Hässler, A | 1 |
| John, R | 1 |
3 other studies available for phenobarbital and Pancytopenia
| Article | Year |
|---|---|
Pancytopenia secondary to suspected idiosyncratic phenobarbital reaction in a dog.
Topics: Animals; Dog Diseases; Dogs; Male; Pancytopenia; Phenobarbital; Seizures | 2021 |
The Case of the Previously Shaky, Unimmunized, Itchy Infant With Rash and Pancytopenia.
Topics: Anticonvulsants; Antipyretics; Drug Hypersensitivity Syndrome; Exanthema; Humans; Infant; Male; Panc | 2016 |
[Panmyelopathy in combined epilepsy therapy using ethosuccimide, diphenylhydantoin, and phenobarbital in childhood].
Topics: Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Pancytopenia; Phenobarbita | 1980 |