phenobarbital has been researched along with Pancreatic Neoplasms in 4 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " injection of nitrosomethylurea (NMU) in 3-day-old rats orally treated with the pesticide mancozeb (MZ), the flavonoid quercetin (Q) or in combination (MZ-Q) induces hyperplasia, atypical acinar cell proliferation and carcinoma in situ (CIS) in the pancreas." | 3.73 | Effect of the co-administration of phenobarbital, quercetin and mancozeb on nitrosomethylurea-induced pancreatic tumors in rats. ( Barotto, NN; Bongiovanni, GA; Díaz, MP; Eynard, AR; Valentich, MA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moore, AR | 1 |
| Chu, C | 1 |
| Singh, K | 1 |
| Barger, AM | 1 |
| Schnelle, AN | 1 |
| Valentich, MA | 1 |
| Eynard, AR | 1 |
| Barotto, NN | 1 |
| Díaz, MP | 1 |
| Bongiovanni, GA | 1 |
| Makino, T | 1 |
| Obara, T | 1 |
| Ura, H | 1 |
| Kinugasa, T | 1 |
| Kobayashi, H | 1 |
| Takahashi, S | 1 |
| Konishi, Y | 1 |
| Buist, NR | 1 |
| Campbell, JR | 1 |
| Castro, A | 1 |
4 other studies available for phenobarbital and Pancreatic Neoplasms
| Article | Year |
|---|---|
What is your diagnosis? Liver aspirate from a hypoglycemic dog.
Topics: Abdomen; Animals; Anticonvulsants; Biopsy, Fine-Needle; Dog Diseases; Dogs; Euthanasia, Animal; Hypo | 2015 |
Effect of the co-administration of phenobarbital, quercetin and mancozeb on nitrosomethylurea-induced pancreatic tumors in rats.
Topics: Alkylating Agents; Animals; Animals, Newborn; Carcinogens; Carcinoma in Situ; Disease Models, Animal | 2006 |
Effects of phenobarbital and secondary bile acids on liver, gallbladder, and pancreas carcinogenesis initiated by N-nitrosobis (2-hydroxypropyl)amine in hamsters.
Topics: Adenoma, Bile Duct; Animals; Bile Acids and Salts; Cocarcinogenesis; Cricetinae; Deoxycholic Acid; E | 1986 |
Congenital islet cell adenoma causing hypoglycemia in a newborn.
Topics: Adenoma, Islet Cell; Blood Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Ne | 1971 |