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phenobarbital and Palsy

phenobarbital has been researched along with Palsy in 39 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
" The data obtained show that phenobarbital and chlordane decrease zoxazolamine paralysis time and increase liver weight and biliary flow."3.67Effects of phenobarbital, chlordane, and oxytetracycline on DDT excretion in rats. ( Doki, M; Puga, FR; Rodrigues, MA, 1986)
"The effects of modifiers of the microsomal mixed-function oxidase system on acrylamide-induced hind-limb paralysis were investigated in rats."3.67Effects of mixed-function oxidase modifiers on neurotoxicity of acrylamide in rats. ( Das, M; Mukhtar, H; Seth, PK; Srivastava, SP, 1985)
"Zoxazolamine paralysis, hexobarbital anesthesia and digitoxin convulsions were diminished in rats by 3 days of pretreatment with pregnenolone-16alpha-carbonitrile (PCN)."3.65Studies on drug metabolism and liver ultrastructure after conjoint treatment with pregnenolone-16alpha-carbonitrile and dl-ethionine. ( Garg, BD; Kourounakis, P; Kovacs, K; Szabo, S; Tuchweber, B, 1977)
"These were presence of seizures, grading of encephalopathy and neurobehavioural assessment at discharge from the hospital."1.30Clinical predictors of outcome in hypoxic ischaemic encephalopathy in term neonates. ( Aggarwal, P; Barve, S; Bhave, S; Chaudhari, S; Pandit, A, 1998)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199037 (94.87)18.7374
1990's2 (5.13)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
OKUDA, O1
SHINOHARA, S1
WAITZOVA, D1
SOBEK, V1
HAVA, M1
KARGEROVA, A1
Lenn, NJ1
Hamill, JS1
Short, RD1
Lee, CC1
Monnet, FP1
Debonnel, G1
de Montigny, C1
Aggarwal, P1
Chaudhari, S1
Bhave, S1
Pandit, A1
Barve, S1
Frontali, N1
Guarcini, AM1
Spagnolo, A1
Amantini, MC1
Chow, CP1
Cornish, HH1
Botez, MI1
Peyronnard, JM1
Bérubé, L1
Labrecque, R1
Unseld, A1
de Matteis, F1
Garg, BD2
Kourounakis, P1
Tuchweber, B2
Szabo, S2
Kovacs, K1
Mathur, PP1
Smyth, RD1
Witmer, CM1
Carr, GS1
Reavey-Cantwell, NH1
Wiebel, FJ1
Waters, HL1
Elliot, S1
Gelboin, HV1
Salas, M1
Puga, FR1
Rodrigues, MA1
Doki, M1
Srivastava, SP1
Seth, PK1
Das, M1
Mukhtar, H1
Selye, H1
Mécs, I1
Marsden, CD1
Reynolds, EH1
Parsons, V1
Harris, R1
Duchen, L1
Arseni, C1
Marinescu, V1
Kramer, S1
Viljoen, D1
Becker, D1
Metz, J1
Kato, R3
Takanaka, A3
Klaassen, CD1
Freund, G1
Murphy, JP1
Van Stee, EW1
Back, KC1
Haase, J1
Jepsen, BV1
Bech, H1
Langeback, E1
Yamamoto, K1
Sawada, T1
Naito, Y1
Kido, R1
Buu-Hoï, NP1
Hien, DP1
Saint-Ruf, G1
Servoin-Sidoine, J1
Stenger, RJ2
Johnson, EA2
Chen, FC1
Cavanagh, JB1
Brodeur, J1
Marchand, C1
Abernathy, CO1
Philpot, RM1
Guthrie, FE1
Hodgson, E1
Breckenridge, A2
Orme, M1
Oshima, T1
Kretzschmar, R2
Meyer, HJ2
Teschendorf, HJ2
Zöllner, B1
Davies, DS1
Orme, ML1
Thorgeirsson, S1
Straw, RN1
Mitchell, CL1

Reviews

1 review available for phenobarbital and Palsy

ArticleYear
[Substances capable of inducing polyneuropathies, used in the shoe industry (triarylphosphates, aliphatic hydrocarbons, C5-C7)].
    Annali dell'Istituto superiore di sanita, 1979, Volume: 15, Issue:2

    Topics: Acetylcholinesterase; Air Pollutants; Air Pollutants, Occupational; Alkanes; Animals; Birds; Butyryl

1979

Other Studies

38 other studies available for phenobarbital and Palsy

ArticleYear
[OBSERVATION ON TWO CASES OF EPILEPSIA CURSIVA].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1964, Volume: 66

    Topics: Adolescent; Atrophy; Barbiturates; Cerebral Cortex; Chlordiazepoxide; Dichlorphenamide; Electroencep

1964
STUDIES ON DETOXIFICATION OF NEOMYCIN.
    Toxicology and applied pharmacology, 1965, Volume: 7

    Topics: Calcium Chloride; Central Nervous System; Cerebral Ventricles; Chlorides; Desoxycorticosterone; Dihy

1965
Congenital radial nerve pressure palsy.
    Clinical pediatrics, 1983, Volume: 22, Issue:5

    Topics: Female; Humans; Infant, Newborn; Male; Nerve Compression Syndromes; Paralysis; Phenobarbital; Pregna

1983
Effect of some nitrotoluenes on the biotransformation of xenobiotics in rats.
    Experientia, 1980, Jan-15, Volume: 36, Issue:1

    Topics: Animals; Biotransformation; Dinitrobenzenes; Male; Nitrobenzenes; Paralysis; Phenobarbital; Rats; Sl

1980
The cytochromes P-450 are not involved in the modulation of the N-methyl-D-aspartate response by sigma ligands in the rat CA3 dorsal hippocampus.
    Synapse (New York, N.Y.), 1993, Volume: 13, Issue:1

    Topics: Animals; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electrophysiology; Guanid

1993
Clinical predictors of outcome in hypoxic ischaemic encephalopathy in term neonates.
    Annals of tropical paediatrics, 1998, Volume: 18, Issue:2

    Topics: Anticonvulsants; Apgar Score; Asphyxia Neonatorum; Cerebral Palsy; Cerebrovascular Disorders; Female

1998
Effects of lead on the induction of hepatic microsomal enzymes by phenobarbital and 3,4-benzpyrene.
    Toxicology and applied pharmacology, 1978, Volume: 43, Issue:2

    Topics: Animals; Benzopyrenes; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Drug Interactions; Enz

1978
Relapsing neuropathy, cerebral atrophy and folate deficiency. A close association.
    Applied neurophysiology, 1979, Volume: 42, Issue:3

    Topics: Atrophy; Brain Diseases; Edema; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intesti

1979
Destruction of endogenous and exogenous haem by 2-allyl-2-isopropylacetamide: role of the liver cytochrome P-450 which is inducible by phenobarbitone.
    The International journal of biochemistry, 1978, Volume: 9, Issue:12

    Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; E

1978
Studies on drug metabolism and liver ultrastructure after conjoint treatment with pregnenolone-16alpha-carbonitrile and dl-ethionine.
    Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 227, Issue:2

    Topics: Animals; Digitoxin; Drug Interactions; Ethionine; Female; Hexobarbital; In Vitro Techniques; Liver;

1977
Temporal pattern and reversal of impaired hepatic mono-oxygenases by phenobarbital in rats with developing and established adjuvant disease.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 203, Issue:1

    Topics: Animals; Arthritis; Arthritis, Experimental; Cytochromes; Hexobarbital; Male; Microsomes, Liver; Oxy

1977
Effect of 7 8-benzoflavone on the duration of zoxazolamine paralysis and hexobarbital hypnosis in rats.
    Biochemical pharmacology, 1976, Jun-15, Volume: 25, Issue:12

    Topics: Animals; Depression, Chemical; Flavonoids; Hexobarbital; Male; Methylcholanthrene; Paralysis; Phenob

1976
Microsomal enzyme inducers and hypervitaminosis A in rats.
    Archives of pathology & laboratory medicine, 1976, Volume: 100, Issue:2

    Topics: Animals; Bone Diseases; Enzyme Induction; Female; Liver; Microsomes, Liver; Paralysis; Phenobarbital

1976
Effects of phenobarbital, chlordane, and oxytetracycline on DDT excretion in rats.
    Ecotoxicology and environmental safety, 1986, Volume: 12, Issue:3

    Topics: Animals; Bile; Chlordan; DDT; Male; Oxytetracycline; Paralysis; Phenobarbital; Rats; Rats, Inbred St

1986
Effects of mixed-function oxidase modifiers on neurotoxicity of acrylamide in rats.
    Biochemical pharmacology, 1985, Apr-01, Volume: 34, Issue:7

    Topics: Acrylamide; Acrylamides; Animals; Cobalt; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Mal

1985
Protection by catatoxic steroids against the paralysis caused by combined treatment with thyroxine and methylphenidate.
    Neuropharmacology, 1972, Volume: 11, Issue:5

    Topics: Androstenols; Animals; Drug Synergism; Estradiol; Ethylestrenol; Female; Humans; Hydroxysteroids; Hy

1972
Myopathy associated with anticonvulsant osteomalacia.
    British medical journal, 1973, Dec-01, Volume: 4, Issue:5891

    Topics: Adult; Anticonvulsants; Back Pain; Depression; Electroencephalography; Electromyography; Ergocalcife

1973
Epilepsy in cerebral hydatidosis.
    Epilepsia, 1974, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Brain Diseases; Child; Child, Preschool; Dominance, Cerebral; Echinococcosis; Ele

1974
A possible explanation for the neurological disturbances in the porphyrias.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1971, Sep-25

    Topics: Adenosine Triphosphatases; Amino Acids; Animals; Brain; Cystine; Erythrocytes; Glycine; Humans; Levu

1971
Effect of starvation on the in vivo metabolism and effect of drugs in female and male rats.
    Japanese journal of pharmacology, 1967, Volume: 17, Issue:2

    Topics: Amides; Anesthesia; Animals; Barbiturates; Body Weight; Carisoprodol; Diphosphates; Female; Hexobarb

1967
Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 191, Issue:2

    Topics: Analysis of Variance; Animals; Bile; Biotransformation; Cardiac Glycosides; Digitoxin; Digoxin; Dose

1974
Alcohol, barbiturate, and bromide withdrawal syndromes in mice.
    Annals of the New York Academy of Sciences, 1973, Apr-30, Volume: 215

    Topics: Alcohol Drinking; Alcoholism; Animals; Barbiturates; Body Weight; Bromides; Diet; Disease Models, An

1973
Effect of dibromotetrafluoroethane inhalation on hepatic drug metabolism in mice.
    Biochemical pharmacology, 1973, Nov-15, Volume: 22, Issue:22

    Topics: Animals; Chlorofluorocarbons, Methane; Drug Interactions; Hexobarbital; Hydrocarbons, Halogenated; L

1973
Spinal fracture following radiculography using meglumine iothalamate (Conray).
    Neuroradiology, 1973, Volume: 6, Issue:2

    Topics: Adipates; Adult; Contrast Media; Diazepam; Female; Fractures, Bone; Humans; Hypesthesia; Iothalamic

1973
[Neuropharmacologic study on the effect of nitrazepam on the central nervous system].
    No to shinkei = Brain and nerve, 1969, Volume: 21, Issue:5

    Topics: Aggression; Amygdala; Animals; Appetitive Behavior; Behavior, Animal; Benzazepines; Brain; Cats; Cer

1969
[Canceromimetic properties of the tetrachloro-2,3,7,8 dibenzo-p-dioxin ("dioxin")].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Mar-08, Volume: 272, Issue:10

    Topics: Animals; Arginase; Carcinogens; Dioxins; Enzyme Induction; Glycolates; Liver; Liver Neoplasms; Male;

1971
Modifying effect of 3-amino-1,2,4-triazole on phenobarbital-induced changes in rat liver.
    Experimental and molecular pathology, 1972, Volume: 16, Issue:2

    Topics: Amitrole; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochrom

1972
Effects of phenobarbital pretreatment on the response of rat liver to halothane administration.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 140, Issue:4

    Topics: Anesthesia, General; Animals; Chemical and Drug Induced Liver Injury; Cytochromes; Enzyme Induction;

1972
Factors affecting neurotoxicity by p-bromophenylacetylurea in rats.
    British journal of experimental pathology, 1971, Volume: 52, Issue:3

    Topics: Acetylcholinesterase; Age Factors; Animals; Biotransformation; Carbon Tetrachloride Poisoning; Chemi

1971
Effect of splenectomy on the activity of drug-metabolizing enzymes in the liver of rats.
    Canadian journal of physiology and pharmacology, 1971, Volume: 49, Issue:3

    Topics: Animals; Anisoles; Biological Assay; Carbon Isotopes; Cytochromes; Enzyme Induction; Female; Hexobar

1971
Inductive effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane(DDT), phenobarbital, and benzpyrene on microsomal cytochrome B450, ethyl isocyanide spectra, and metabolism in vivo of zoxazolamine and hexobarbital in the mouse.
    Biochemical pharmacology, 1971, Volume: 20, Issue:9

    Topics: Animals; Benzopyrenes; Cyanides; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Hexobarbital

1971
Clinical implications of enzyme induction.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Alcohols; Amobarbital; Animals; Antipyrine; Benzazepines; Blood Coagulation; Chloral Hydrate; Chlord

1971
Drug metabolism in tumor-bearing rats. II. In vivo metabolisms and effects of drugs in tumor-bearing rats.
    Japanese journal of pharmacology, 1968, Volume: 18, Issue:2

    Topics: Anesthesia; Animals; Carcinoma 256, Walker; Carisoprodol; Cholinesterase Inhibitors; Female; Injecti

1968
Metabolism of drugs in old rats. II. Metabolism in vivo and effect of drugs in old rats.
    Japanese journal of pharmacology, 1968, Volume: 18, Issue:4

    Topics: Aging; Anesthesia; Animals; Carisoprodol; Female; Hexobarbital; Injections, Intraperitoneal; Insecti

1968
[Antagonistic action of natural 5,6-hydrogenated Kava pyrones against strychnine poisoning and experimental local tetanus].
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2

    Topics: Anesthetics; Animals; Antidotes; Ataxia; Electromyography; Isonicotinic Acids; Male; Mephenesin; Mic

1969
Strychnine antagonistic potency of pyrone compounds of the kavaroot (Piper methysticum Forst.).
    Experientia, 1970, Mar-15, Volume: 26, Issue:3

    Topics: Animals; Mephenesin; Mice; Paralysis; Phenobarbital; Plants, Medicinal; Pyrans; Reflex; Seizures; St

1970
Screening methods for measuring liver microsomal enzyme induction by drugs.
    The Journal of physiology, 1969, Volume: 202, Issue:1

    Topics: Animals; Carbon Isotopes; Enzyme Induction; Liver; Male; Microsomes; Paralysis; Phenobarbital; Rats;

1969
Effect of phenobarbital on cortical after-discharge and overt seizure patterns in the cat.
    International journal of neuropharmacology, 1966, Volume: 5, Issue:4

    Topics: Animals; Cats; Cerebral Cortex; Cortical Spreading Depression; Electroencephalography; Electrophysio

1966