phenobarbital has been researched along with Ovine Diseases in 11 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Apart from the hyperbilirubinemia (which comprised around 50% of conjugated bilirubin), usual hepatic function tests were normal." | 7.65 | Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep. ( Berthelot, P; Dhumeaux, D, 1975) |
| " Apart from the hyperbilirubinemia (which comprised around 50% of conjugated bilirubin), usual hepatic function tests were normal." | 3.65 | Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep. ( Berthelot, P; Dhumeaux, D, 1975) |
| "Albendazole (ABZ) is an anthelmintic frequently used to treat haemonchosis, a common parasitosis of ruminants caused by the gastrointestinal nematode Haemonchus contortus." | 1.72 | The induction and inhibition of UDP-glycosyltransferases in Haemonchus contortus and their role in the metabolism of albendazole. ( Ambrož, M; Dimunová, D; Kellerová, P; Matoušková, P; Navrátilová, M; Skálová, L, 2022) |
| " Induction by phenobarbitone provided a degree of protection against the toxic effects of B." | 1.31 | Effect of phenobarbitone treatment against signal grass (Brachiaria decumbens) toxicity in sheep. ( Abdullah, AS; Elsheikh, HA; Hasiah, AH; Khairi, HM; Rajion, MA, 2000) |
| " There was no difference in NADPH-cytochrome c reductase or 7-ethoxyresorufin-O-deethylase (EROD) activity between ewes, control lambs and phenobarbitone-dosed lambs 3 weeks after dosing ceased." | 1.28 | Microsomal enzymes in lambs and adult sheep, and their possible relationship to alveld. ( Flåøyen, A; Jensen, EG, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Dimunová, D | 1 |
| Navrátilová, M | 1 |
| Kellerová, P | 1 |
| Ambrož, M | 1 |
| Skálová, L | 1 |
| Matoušková, P | 1 |
| Seawright, AA | 3 |
| McLean, AE | 1 |
| Hasiah, AH | 1 |
| Elsheikh, HA | 1 |
| Abdullah, AS | 1 |
| Khairi, HM | 1 |
| Rajion, MA | 1 |
| Silvestri, R | 1 |
| Himes, JA | 2 |
| Edds, GT | 2 |
| Dhumeaux, D | 1 |
| Berthelot, P | 1 |
| Flåøyen, A | 2 |
| Grønstøl, H | 1 |
| Søli, NE | 1 |
| Jensen, EG | 1 |
| Shetty, SN | 1 |
| Allen, JG | 1 |
| Steele, DP | 1 |
| Mudie, AW | 1 |
| Bishop, R | 1 |
| Gallagher, CH | 1 |
| Koch, JH | 1 |
| Hoffman, H | 1 |
11 other studies available for phenobarbital and Ovine Diseases
| Article | Year |
|---|---|
The induction and inhibition of UDP-glycosyltransferases in Haemonchus contortus and their role in the metabolism of albendazole.
Topics: Albendazole; Animals; Anthelmintics; Glycosides; Glycosyltransferases; Haemonchus; Nematoda; Phenoba | 2022 |
Induced susceptibility of sheep to carbon tetrachloride intoxication.
Topics: Animals; Bilirubin; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced | 1967 |
Effect of phenobarbitone treatment against signal grass (Brachiaria decumbens) toxicity in sheep.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Cytochrome P-450 Enzyme System; Enzyme Indu | 2000 |
Repeated oral administration of coumaphos in sheep: interactions of coumaphos with bishydroxycoumarin, trichlorfon, and phenobarbital sodium.
Topics: Acetylcholinesterase; Administration, Oral; Animals; Cholinesterase Inhibitors; Coumaphos; Dicumarol | 1975 |
Chronic hyperbilirubinemia associated with hepatic uptake and storage impairment. A new syndrome resembling that of the mutant Southdown sheep.
Topics: Adult; Animals; Bilirubin; Female; Humans; Hyperbilirubinemia; Liver; Mutation; Phenobarbital; Sheep | 1975 |
Treatment of lambs with phenobarbitone is not effective against alveld under practical conditions in Norway.
Topics: Animals; Female; Male; Norway; Phenobarbital; Photosensitivity Disorders; Sheep; Sheep Diseases | 1991 |
Microsomal enzymes in lambs and adult sheep, and their possible relationship to alveld.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Disease Susceptibility; Female; Gl | 1991 |
Effect of phenobarbital on bishydroxycoumarin plasma concentrations and hypoprothrombinemic responses in sheep.
Topics: Administration, Oral; Animals; Dicumarol; Drug Interactions; Female; Hypoprothrombinemias; Injection | 1972 |
The effect of prior treatment with phenobarbitone, dicophane (DDT) and beta-diethylaminoethyl phenylpropyl acetate (SKF 525A) on experimental intoxication of sheep with the plant Myoporum deserti Cunn.
Topics: Animals; Bilirubin; Biopsy; DDT; Edema; Eosinophils; Gallbladder; Gastrointestinal Hemorrhage; Ische | 1973 |
The effect of diet and drugs on hepatic microsomal aminopyrine N-demethylase activity in vitro and susceptibility to carbon tetrachloride in sheep.
Topics: Aminopyrine; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; DDT; Diet; Dietary Prote | 1972 |
Electro-myographic studies on sheep injected with the N,N-dimethylated tryptamine alkaloids of Phalaris tuberosa.
Topics: Alkaloids; Animals; Barbiturates; Cordotomy; Electric Stimulation; Electromyography; Injections, Int | 1967 |