Page last updated: 2024-11-02

phenobarbital and Ornithine Carbamoyltransferase Deficiency Disease

phenobarbital has been researched along with Ornithine Carbamoyltransferase Deficiency Disease in 1 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Ornithine Carbamoyltransferase Deficiency Disease: An inherited urea cycle disorder associated with deficiency of the enzyme ORNITHINE CARBAMOYLTRANSFERASE, transmitted as an X-linked trait and featuring elevations of amino acids and ammonia in the serum. Clinical features, which are more prominent in males, include seizures, behavioral alterations, episodic vomiting, lethargy, and coma. (Menkes, Textbook of Child Neurology, 5th ed, pp49-50)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Qureshi, IA1
Lebel, S1
Letarte, J1

Other Studies

1 other study available for phenobarbital and Ornithine Carbamoyltransferase Deficiency Disease

ArticleYear
Development and inducibility of the hepatic and renal hippurate-synthesizing system in sparse-fur (spf) mutant mice with ornithine transcarbamylase deficiency.
    Biochemistry international, 1989, Volume: 19, Issue:3

    Topics: Acyltransferases; Animals; Benzoates; Benzoic Acid; Enzyme Induction; Hippurates; Kidney Cortex; Liv

1989