phenobarbital has been researched along with Onchocerciasis in 2 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Onchocerciasis: Infection with nematodes of the genus ONCHOCERCA. Characteristics include the presence of firm subcutaneous nodules filled with adult worms, PRURITUS, and ocular lesions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nodding syndrome is a highly debilitating, generalized seizure disorder, affecting children in subregions of sub-Saharan Africa." | 1.56 | Dried Blood Microsampling-Based Therapeutic Drug Monitoring of Antiepileptic Drugs in Children With Nodding Syndrome and Epilepsy in Uganda and the Democratic Republic of the Congo. ( Colebunders, R; Delahaye, L; Hotterbeekx, A; Idro, R; Mandro, M; Ogwang, R; Stove, CP; Velghe, S, 2020) |
| "Phenobarbital was the antiepileptic drug most commonly prescribed in 76." | 1.51 | Clinical presentation of epilepsy in six villages in an onchocerciasis endemic area in Mahenge, Tanzania. ( Bhwana, D; Colebunders, R; Dekker, MC; Kakorozya, A; Makunde, WH; Matuja, W; Mmbando, BP; Mnacho, M; Weckhuysen, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhwana, D | 1 |
| Mmbando, BP | 1 |
| Dekker, MC | 1 |
| Mnacho, M | 1 |
| Kakorozya, A | 1 |
| Matuja, W | 1 |
| Makunde, WH | 1 |
| Weckhuysen, S | 1 |
| Colebunders, R | 2 |
| Velghe, S | 1 |
| Delahaye, L | 1 |
| Ogwang, R | 1 |
| Hotterbeekx, A | 1 |
| Mandro, M | 1 |
| Idro, R | 1 |
| Stove, CP | 1 |
2 other studies available for phenobarbital and Onchocerciasis
| Article | Year |
|---|---|
Clinical presentation of epilepsy in six villages in an onchocerciasis endemic area in Mahenge, Tanzania.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Male; Neurologists; Onchocerciasis; Phenobarbital; | 2019 |
Dried Blood Microsampling-Based Therapeutic Drug Monitoring of Antiepileptic Drugs in Children With Nodding Syndrome and Epilepsy in Uganda and the Democratic Republic of the Congo.
Topics: Anticonvulsants; Carbamazepine; Child; Chromatography, Liquid; Democratic Republic of the Congo; Dri | 2020 |