phenobarbital has been researched along with Neutropenia in 5 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Sensitivity to phenobarbital and related anticonvulsants may induce life-threatening leukopenia, thrombocytopenia, and anemia in dogs." | 3.70 | Neutropenia and thrombocytopenia in three dogs treated with anticonvulsants. ( Calvert, C; Jacobs, G; Kaufman, A, 1998) |
| "Hypothermia was associated with a decreased number of circulating PMNs but did not increase the number of neurologically intact survivors." | 1.27 | Influence of hypothermia, barbiturate therapy, and intracranial pressure monitoring on morbidity and mortality after near-drowning. ( Barker, GA; Biggar, WD; Bohn, DJ; Conn, AW; Smith, CR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Savaşan, S | 1 |
| Ozgönenel, B | 1 |
| Taub, JW | 1 |
| Hamre, M | 1 |
| Jacobs, G | 1 |
| Calvert, C | 1 |
| Kaufman, A | 1 |
| Sturgill, MG | 1 |
| August, DA | 1 |
| Brenner, DE | 1 |
| Vaĭntrub, MIa | 1 |
| Shapiro, IuL | 1 |
| Bohn, DJ | 1 |
| Biggar, WD | 1 |
| Smith, CR | 1 |
| Conn, AW | 1 |
| Barker, GA | 1 |
5 other studies available for phenobarbital and Neutropenia
| Article | Year |
|---|---|
Elevated serum cobalamin levels in childhood autoimmune and drug-induced neutropenia.
Topics: Adolescent; Autoimmune Diseases; Child, Preschool; Erythema Multiforme; Humans; Neutropenia; Phenoba | 2004 |
Neutropenia and thrombocytopenia in three dogs treated with anticonvulsants.
Topics: Anemia; Animals; Anticonvulsants; Bacteremia; Blood Cell Count; Dog Diseases; Dogs; Female; Male; Ne | 1998 |
Hepatic enzyme induction with phenobarbital and doxorubicin metabolism and myelotoxicity in the rabbit.
Topics: Animals; Antineoplastic Agents; Doxorubicin; Drug Interactions; Enzyme Induction; Female; Hypnotics | 2000 |
[Neutropenia in epilepsy patients].
Topics: Adolescent; Adult; Agranulocytosis; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epile | 1979 |
Influence of hypothermia, barbiturate therapy, and intracranial pressure monitoring on morbidity and mortality after near-drowning.
Topics: Adolescent; Child; Child, Preschool; Drowning; Humans; Hypothermia; Hypothermia, Induced; Infant; In | 1986 |