phenobarbital has been researched along with Neuronal Ceroid-Lipofuscinoses in 1 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Neuronal Ceroid-Lipofuscinoses: A group of severe neurodegenerative diseases characterized by intracellular accumulation of autofluorescent wax-like lipid materials (CEROID; LIPOFUSCIN) in neurons. There are several subtypes based on mutations of the various genes, time of disease onset, and severity of the neurological defects such as progressive DEMENTIA; SEIZURES; and visual failure.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aberg, LE | 1 |
| Bäckman, M | 1 |
| Kirveskari, E | 1 |
| Santavuori, P | 1 |
1 trial available for phenobarbital and Neuronal Ceroid-Lipofuscinoses
| Article | Year |
|---|---|
Epilepsy and antiepileptic drug therapy in juvenile neuronal ceroid lipofuscinosis.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbidity; | 2000 |