phenobarbital has been researched along with Neoplasm Metastasis in 11 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the role of monomethyltriazenes as the active metabolites of antitumor dimethyltriazenes, the in vivo simultaneous treatment with an inducer (phenobarbital, PB) or an inhibitor (carbon tetrachloride, CCl4) of hepatic drug metabolism was examined in mice bearing Lewis lung carcinoma." | 3.67 | Effects of an inducer and an inhibitor of hepatic metabolism on the antitumor action of dimethyltriazenes. ( Giraldi, T; Lassiani, L; Perissin, L; Sava, G; Zorzet, S, 1988) |
| "Seventy patients died (unrelated to seizures) and survival rates were equivalent in both groups (median survival = 6." | 2.71 | Prophylactic anticonvulsants in patients with brain tumour. ( Barnes, P; Brasher, PM; Cairncross, JG; DeAngelis, LM; Forsyth, PA; Fulton, D; Hagen, NA; Stewart, D; Sutherland, G; Weaver, S, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Forsyth, PA | 1 |
| Weaver, S | 1 |
| Fulton, D | 1 |
| Brasher, PM | 1 |
| Sutherland, G | 1 |
| Stewart, D | 1 |
| Hagen, NA | 1 |
| Barnes, P | 1 |
| Cairncross, JG | 1 |
| DeAngelis, LM | 1 |
| Lindenschmidt, TO | 1 |
| Zimmermann, HG | 1 |
| Pitot, HC | 1 |
| Wallace, EZ | 1 |
| Rosman, PM | 1 |
| Balthazar, A | 1 |
| Sacerdote, A | 1 |
| Fullerton, FR | 1 |
| Hoover, K | 1 |
| Mikol, YB | 1 |
| Creasia, DA | 1 |
| Poirier, LA | 1 |
| Sava, G | 1 |
| Zorzet, S | 1 |
| Perissin, L | 1 |
| Giraldi, T | 1 |
| Lassiani, L | 1 |
| Thorpe, E | 1 |
| Walker, AI | 1 |
| Sadoff, L | 1 |
| Riley, S | 1 |
| Quan, L | 1 |
| Rowe, J | 1 |
| Bertram, JS | 1 |
| Craig, AW | 1 |
| Hendricks, GL | 1 |
| Barnes, WT | 1 |
| Hood, HL | 1 |
| van den Brenk, HA | 1 |
| Sharpington, C | 1 |
1 trial available for phenobarbital and Neoplasm Metastasis
| Article | Year |
|---|---|
Prophylactic anticonvulsants in patients with brain tumour.
Topics: Anticonvulsants; Brain Neoplasms; Disease Progression; Female; Humans; Incidence; Male; Middle Aged; | 2003 |
10 other studies available for phenobarbital and Neoplasm Metastasis
| Article | Year |
|---|---|
[Surgical laparoscopy].
Topics: Biopsy; Breast Neoplasms; Humans; Laparoscopy; Liver Neoplasms; Lung Neoplasms; Neoplasm Metastasis; | 1975 |
The stability of events in the natural history of neoplasia.
Topics: Animals; Carcinoma, Hepatocellular; Humans; Liver; Liver Neoplasms; Mammary Neoplasms, Experimental; | 1977 |
Adrenocortical carcinoma in a patient with systemic lupus erythematosus treated with azathioprine.
Topics: Adrenal Cortex Neoplasms; Azathioprine; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Ne | 1979 |
The inhibition by methionine and choline of liver carcinoma formation in male C3H mice dosed with diethylnitrosamine and fed phenobarbital.
Topics: Animals; Choline; Diethylnitrosamine; Liver; Liver Neoplasms, Experimental; Male; Methionine; Mice; | 1990 |
Effects of an inducer and an inhibitor of hepatic metabolism on the antitumor action of dimethyltriazenes.
Topics: Animals; Antineoplastic Agents; Biotransformation; Carbon Tetrachloride; Carcinoma; Liver; Lung Neop | 1988 |
The toxicology of dieldrin (HEOD). II. Comparative long-term oral toxicity studies in mice with dieldrin, DDT, phenobarbitone, -BHC and -BHC.
Topics: Administration, Oral; Animals; DDT; Dieldrin; Female; Hepatomegaly; Hexachlorocyclohexane; Hyperplas | 1973 |
New endocrine observations in a male patient with choriocarcinoma.
Topics: Adult; Brain Neoplasms; Cerebrospinal Fluid Proteins; Choriocarcinoma; Cyclophosphamide; Dactinomyci | 1974 |
Specific induction of bladder cancer in mice by butyl-(4-hydroxybutyl)-nitrosamine and the effects of hormonal modifications on the sex difference in response.
Topics: Animals; Castration; Female; Male; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Nitrosamines; | 1972 |
Seven-year "cure" of lung cancer with metastasis to the brain.
Topics: Adenocarcinoma; Brain Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Phe | 1972 |
Effect of phenobarbital on growth of a metastasising, allogeneic sarcoma in the rat.
Topics: Animals; Body Weight; Cobalt Isotopes; Female; Immunosuppression Therapy; Lung Neoplasms; Lymphatic | 1972 |