phenobarbital has been researched along with Myocarditis in 3 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Myocarditis: Inflammatory processes of the muscular walls of the heart (MYOCARDIUM) which result in injury to the cardiac muscle cells (MYOCYTES, CARDIAC). Manifestations range from subclinical to sudden death (DEATH, SUDDEN). Myocarditis in association with cardiac dysfunction is classified as inflammatory CARDIOMYOPATHY usually caused by INFECTION, autoimmune diseases, or responses to toxic substances. Myocarditis is also a common cause of DILATED CARDIOMYOPATHY and other cardiomyopathies.
| Excerpt | Relevance | Reference |
|---|---|---|
| " He developed many annular skin eruptions and peripheral eosinophilia due to reactions against phenobarbital." | 7.70 | Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital. ( Arima, M; Kanoh, T; Kasuya, H; Kawai, S; Matsuda, S; Okada, R; Sunayama, S; Yamasaki, A, 1998) |
| " He developed many annular skin eruptions and peripheral eosinophilia due to reactions against phenobarbital." | 3.70 | Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital. ( Arima, M; Kanoh, T; Kasuya, H; Kawai, S; Matsuda, S; Okada, R; Sunayama, S; Yamasaki, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KOTATKO, J | 1 |
| Arima, M | 1 |
| Kanoh, T | 1 |
| Yamasaki, A | 1 |
| Matsuda, S | 1 |
| Kasuya, H | 1 |
| Sunayama, S | 1 |
| Kawai, S | 1 |
| Okada, R | 1 |
| Lannek, B | 1 |
3 other studies available for phenobarbital and Myocarditis
| Article | Year |
|---|---|
THE EFFECT OF PHENOBARBITAL ON THE ELECTROCARDIOGRAM IN ACUTE MYOCARDITIS.
Topics: Biometry; Electrocardiography; Humans; Injections; Injections, Subcutaneous; Mitral Valve Prolapse; | 1965 |
Eosinophilic myocarditis associated with toxicodermia caused by phenobarbital.
Topics: Adult; Drug Eruptions; Eosinophilia; Heart Failure; Humans; Hypnotics and Sedatives; Male; Myocardit | 1998 |
Toxicity of halogenated oxyquinolines in dogs. A clinical study. II. History, symptoms, laboratory findings, therapy, and follow-up.
Topics: Animals; Chemical and Drug Induced Liver Injury; Dehydration; Dog Diseases; Dogs; Electrocardiograph | 1974 |