phenobarbital has been researched along with Muscle Rigidity in 4 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The combination of phenobarbital and Tolserol(R) is very satisfactory in controlling the muscular rigidity and spasm in cases of moderately severe tetanus." | 7.63 | Mephenesin as a relaxing agent in the treatment of tetanus; clinical experience in 12 cases. ( GODMAN, HE, 1951) |
| " The combination of phenobarbital and Tolserol(R) is very satisfactory in controlling the muscular rigidity and spasm in cases of moderately severe tetanus." | 3.63 | Mephenesin as a relaxing agent in the treatment of tetanus; clinical experience in 12 cases. ( GODMAN, HE, 1951) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GODMAN, HE | 1 |
| Seghieri, G | 1 |
| De Giorgio, LA | 1 |
| Innocenti, F | 1 |
| Pettiná, G | 1 |
| Zolfanelli, F | 1 |
| Apicella, P | 1 |
| Goto, M | 1 |
| Kondo, M | 1 |
| Fukuda, H | 1 |
| Petersen, EA | 1 |
| Haase, J | 1 |
4 other studies available for phenobarbital and Muscle Rigidity
| Article | Year |
|---|---|
Mephenesin as a relaxing agent in the treatment of tetanus; clinical experience in 12 cases.
Topics: Mephenesin; Muscle Rigidity; Phenobarbital; Spasm; Tetanus; Tetanus Toxoid; Tracheotomy | 1951 |
[Description of a case of a syndrome similar to Reye's syndrome in a male adult undergoing treatment with valproic acid and phenobarbital].
Topics: Adult; Brain Diseases; Coma; Epilepsy, Tonic-Clonic; Fever; Humans; Male; Muscle Rigidity; Phenobarb | 1982 |
Effects of barbiturates on the decerebrate rigidity in rats.
Topics: Aminooxyacetic Acid; Amobarbital; Animals; Barbiturates; Decerebrate State; Male; Mephobarbital; Mus | 1982 |
Unstable fractures in children with acute, severe brain injury.
Topics: Accidents, Traffic; Arm Injuries; Brain Injuries; Chlorpromazine; Female; Femoral Fractures; Fractur | 1974 |