phenobarbital has been researched along with Minimally Conscious State in 2 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The duration of the vegetative state was 12 days, 15 days or about 4 months until death and was associated with corresponding stages of generalized ischemic brain damage." | 1.29 | Relationship between ischemic damage and concentrations of phenytoin and phenobarbital in the brain cortex of epileptic patients in vegetative state at death. ( Jürgens, U; Lahl, R; May, T; Rambeck, B; Schnabel, R, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suthar, R | 1 |
| Sankhyan, N | 1 |
| Shree, H | 1 |
| Singhi, P | 1 |
| Schnabel, R | 1 |
| Rambeck, B | 1 |
| May, T | 1 |
| Jürgens, U | 1 |
| Lahl, R | 1 |
2 other studies available for phenobarbital and Minimally Conscious State
| Article | Year |
|---|---|
Reversible Vegetative State in a Child Due to Drug Reaction with Eosinophilia and Systemic Symptoms.
Topics: Adolescent; Anticonvulsants; Child; Drug Hypersensitivity Syndrome; Humans; Persistent Vegetative St | 2017 |
Relationship between ischemic damage and concentrations of phenytoin and phenobarbital in the brain cortex of epileptic patients in vegetative state at death.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Autopsy; Brain Ischemia; Case-Control Studies; Cere | 1996 |