phenobarbital has been researched along with Long QT Syndrome in 2 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we evaluated the effects of phenobarbital and levetiracetam on PR-QTc intervals in patients with post-stroke seizures." | 7.80 | Effects of phenobarbital and levetiracetam on PR and QTc intervals in patients with post-stroke seizure. ( Albertini, G; De Sarro, G; Gallelli, L; Gratteri, S; Iemolo, F; Manes, MT; Mercuri, NB; Quirino, G; Sanzaro, E; Scaglione, F; Siniscalchi, A, 2014) |
| " In this study, we evaluated the effects of phenobarbital and levetiracetam on PR-QTc intervals in patients with post-stroke seizures." | 3.80 | Effects of phenobarbital and levetiracetam on PR and QTc intervals in patients with post-stroke seizure. ( Albertini, G; De Sarro, G; Gallelli, L; Gratteri, S; Iemolo, F; Manes, MT; Mercuri, NB; Quirino, G; Sanzaro, E; Scaglione, F; Siniscalchi, A, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siniscalchi, A | 1 |
| Scaglione, F | 1 |
| Sanzaro, E | 1 |
| Iemolo, F | 1 |
| Albertini, G | 1 |
| Quirino, G | 1 |
| Manes, MT | 1 |
| Gratteri, S | 1 |
| Mercuri, NB | 1 |
| De Sarro, G | 1 |
| Gallelli, L | 1 |
| Yang, Y | 2 |
| Liang, B | 1 |
| Liu, J | 1 |
| Li, J | 1 |
| Grunnet, M | 1 |
| Olesen, SP | 1 |
| Rasmussen, HB | 1 |
| Ellinor, PT | 1 |
| Gao, L | 1 |
| Lin, X | 1 |
| Li, L | 1 |
| Wang, L | 1 |
| Xiao, J | 1 |
| Liu, Y | 2 |
| Zhang, S | 1 |
| Liang, D | 1 |
| Peng, L | 1 |
| Jespersen, T | 1 |
| Chen, YH | 1 |
2 other studies available for phenobarbital and Long QT Syndrome
| Article | Year |
|---|---|
Effects of phenobarbital and levetiracetam on PR and QTc intervals in patients with post-stroke seizure.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Female; Humans; Levetiracetam; Long QT Syndrome; Male; Mid | 2014 |
Identification of a Kir3.4 mutation in congenital long QT syndrome.
Topics: Adolescent; Adult; Aged; Aminophylline; Atropine; Chromosome Mapping; Drug Combinations; Female; G P | 2010 |