phenobarbital has been researched along with Leukomalacia, Periventricular in 4 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Leukomalacia, Periventricular: Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and cognitive disorders. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crowther, CA | 3 |
| Henderson-Smart, DJ | 3 |
| Ruth, V | 1 |
| Virkola, K | 1 |
| Paetau, R | 1 |
| Raivio, KO | 1 |
3 reviews available for phenobarbital and Leukomalacia, Periventricular
| Article | Year |
|---|---|
Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage.
Topics: Central Nervous System Agents; Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Infant, New | 2003 |
Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage.
Topics: Central Nervous System Agents; Cerebral Hemorrhage; Female; Humans; Infant, Newborn; Infant, Prematu | 2000 |
Phenobarbital prior to preterm birth for preventing neonatal periventricular haemorrhage.
Topics: Central Nervous System Agents; Cerebral Hemorrhage; Cerebral Ventricles; Female; Humans; Infant, New | 2001 |
1 trial available for phenobarbital and Leukomalacia, Periventricular
| Article | Year |
|---|---|
Early high-dose phenobarbital treatment for prevention of hypoxic-ischemic brain damage in very low birth weight infants.
Topics: Brain Damage, Chronic; Brain Ischemia; Cerebral Hemorrhage; Developmental Disabilities; Drug Adminis | 1988 |