phenobarbital has been researched along with Leukocytopenia in 11 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report on a patient with epilepsy who developed leukopenia and thrombocytopenia during phenobarbital/lamotrigine treatment." | 7.76 | Phenobarbital/Lamotrigine coadministration-induced blood dyscrasia in a patient with epilepsy. ( Calabrò, G; De Sarro, G; Gallelli, L; Siniscalchi, A; Tolotta, GA, 2010) |
| "To report on a patient with epilepsy who developed leukopenia and thrombocytopenia during phenobarbital/lamotrigine treatment." | 3.76 | Phenobarbital/Lamotrigine coadministration-induced blood dyscrasia in a patient with epilepsy. ( Calabrò, G; De Sarro, G; Gallelli, L; Siniscalchi, A; Tolotta, GA, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Siniscalchi, A | 1 |
| Gallelli, L | 1 |
| Calabrò, G | 1 |
| Tolotta, GA | 1 |
| De Sarro, G | 1 |
| SAFRONOV, EI | 1 |
| Khoutorsky, A | 1 |
| Bruchim, Y | 1 |
| Yassa, R | 1 |
| Nair, V | 1 |
| Schwartz, G | 1 |
| Vaĭntrub, MIa | 1 |
| Shapiro, IuL | 1 |
| Gill, DP | 1 |
| Kempen, RR | 1 |
| Nash, JB | 1 |
| Ellis, S | 1 |
| Cereghino, JJ | 1 |
| Brock, JT | 1 |
| Van Meter, JC | 1 |
| Penry, JK | 1 |
| Smith, LD | 1 |
| White, BG | 1 |
| Hayes, FD | 1 |
| Short, RD | 1 |
| Gibson, JE | 1 |
| Ikeda, M | 1 |
| Otsuji, H | 1 |
| Wierzbowska, A | 1 |
| Radomska, M | 1 |
| Kolodziej, A | 1 |
| Baldwin, RL | 1 |
| Peters, JE | 1 |
1 trial available for phenobarbital and Leukocytopenia
| Article | Year |
|---|---|
Carbamazepine for epilepsy. A controlled prospective evaluation.
Topics: Adult; Blood Cell Count; Bone Marrow Diseases; Carbamazepine; Clinical Trials as Topic; Electroencep | 1974 |
10 other studies available for phenobarbital and Leukocytopenia
| Article | Year |
|---|---|
Phenobarbital/Lamotrigine coadministration-induced blood dyscrasia in a patient with epilepsy.
Topics: Adult; Anticonvulsants; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamo | 2010 |
[A CASE OF RADIATION SICKNESS CAUSED BY INTERNAL IRRADIATION].
Topics: 17-Ketosteroids; Blood Cell Count; Blood Pressure; Blood Protein Electrophoresis; Blood Sedimentatio | 1964 |
Transient leucopenia, thrombocytopenia and anaemia associated with severe acute phenobarbital intoxication in a dog.
Topics: Anemia; Animals; Anti-Anxiety Agents; Dog Diseases; Dogs; Leukopenia; Male; Phenobarbital; Thrombocy | 2008 |
Treatment of leukopenia with lithium carbonate: a preliminary report.
Topics: Adult; Antipsychotic Agents; Drug Evaluation; Female; Humans; Leukopenia; Lithium; Male; Middle Aged | 1978 |
[Neutropenia in epilepsy patients].
Topics: Adolescent; Adult; Agranulocytosis; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epile | 1979 |
Modifications of benzene myelotoxicity and metabolism by phenobarbital, SKF-525A and 3-methylcholanthrene.
Topics: Animals; Benzene; Leukocytosis; Leukopenia; Male; Methylcholanthrene; Phenobarbital; Phenols; Proadi | 1979 |
A correlation between cyclophosphamide induced leukopenia in mice and the presence of alkylating metabolites.
Topics: Alkylating Agents; Animals; Cyclophosphamide; Female; In Vitro Techniques; Kinetics; Leukocyte Count | 1972 |
Phenobarbital-induced protection against toxicity of toluene and benzene in the rat.
Topics: Animals; Benzene; Benzoates; Chromatography, Paper; Chromatography, Thin Layer; Female; Glucuronates | 1971 |
[Hematological control in the treatment of epilepsy].
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Epilepsy; Female; Folic Acid; Hematolo | 1971 |
Hematologic complications from tranquilizers in children.
Topics: Adolescent; Age Factors; Agranulocytosis; Bone Marrow Examination; Brain Damage, Chronic; Brain Dise | 1968 |