phenobarbital has been researched along with Ischemic Attack, Transient in 8 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosenwasser, RH | 1 |
| Buchheit, WA | 1 |
| Truex, RC | 1 |
| Steer, CR | 1 |
| Calderini, G | 1 |
| Carlsson, A | 1 |
| Nordström, CH | 4 |
| Rehncrona, S | 2 |
| Siesjö, BK | 2 |
| Carroll, BJ | 1 |
| Ransohoff, J | 1 |
| Goodgold, A | 1 |
| Benjamin, MV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Continuous Monitoring of Cerebral Metabolic State. Combined Intracerebral and Jugular Bulb Microdialysis in Neurocritical Care.[NCT03314779] | 12 participants (Actual) | Observational | 2017-08-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for phenobarbital and Ischemic Attack, Transient
| Article | Year |
|---|---|
Barbiturate therapy in the management of cerebral ischaemia.
Topics: Animals; Barbiturates; Brain; Brain Edema; Brain Ischemia; Cerebrovascular Circulation; Dogs; Humans | 1982 |
7 other studies available for phenobarbital and Ischemic Attack, Transient
| Article | Year |
|---|---|
Management of subarachnoid hemorrhage.
Topics: Adolescent; Adult; Aminocaproic Acid; Antihypertensive Agents; Child; Cimetidine; Dexamethasone; Hum | 1984 |
Influence of transient ischemia on monoamine metabolism in the rat brain during nitrous oxide and phenobarbitone anaesthesia.
Topics: 5-Hydroxytryptophan; Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Brain; Catecholamines | 1978 |
Restitution of cerebral energy state, as well as of glycolytic metabolites, citric acid cycle intermediates and associated amino acids after 30 minutes of complete ischemia in rats anaesthetized with nitrous oxide or phenobarbital.
Topics: Amino Acids; Anesthesia; Animals; Brain; Citric Acid Cycle; Energy Metabolism; Glycolysis; Ischemic | 1978 |
Influence of phenobarbital on changes in the metabolites of the energy reserve of the cerebral cortex following complete ischemia.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; En | 1978 |
Postischemic cerebral blood flow and oxygen utilization rate in rats anesthetized with nitrous oxide or phenobarbital.
Topics: Anesthesia, General; Animals; Brain; Cerebrovascular Circulation; Ischemic Attack, Transient; Male; | 1977 |
Barbiturate overdosage: presentation with focal neurological signs.
Topics: Adult; Alcoholism; Amobarbital; Barbiturates; Basilar Artery; Bromides; Cerebral Hemorrhage; Coma; C | 1969 |
Preoperative management of patients with ruptured intracranial aneurysms.
Topics: Adult; Aged; Aminocaproates; Antifibrinolytic Agents; Antihypertensive Agents; Blood Pressure; Carot | 1972 |