phenobarbital has been researched along with Intraventricular Septal Defects in 4 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital was observed to produce cardiovascular malformations in embryonic chicks." | 1.27 | The teratogenic effect of phenobarbital on the embryonic chick heart. ( Bruyere, HJ; Gilbert, EF; Matsuoka, R; Nishikawa, T; Takagi, Y, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Panduranga, P | 1 |
| Mukhaini, M | 1 |
| Koie, H | 1 |
| Kurotobi, EN | 1 |
| Sakai, T | 1 |
| Nishikawa, T | 1 |
| Bruyere, HJ | 1 |
| Takagi, Y | 1 |
| Gilbert, EF | 1 |
| Matsuoka, R | 1 |
| Halbrecht, I | 1 |
| Komlos, L | 1 |
| Shabtay, F | 1 |
| Solomon, M | 1 |
| Böök, JA | 1 |
4 other studies available for phenobarbital and Intraventricular Septal Defects
| Article | Year |
|---|---|
A rare type of Gerbode defect.
Topics: Adolescent; Drug Combinations; Heart Septal Defects, Atrial; Heart Septal Defects, Ventricular; Huma | 2011 |
Double-chambered right ventricle in a dog.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Chloramphenicol; Dog Disea | 2000 |
The teratogenic effect of phenobarbital on the embryonic chick heart.
Topics: Abnormalities, Drug-Induced; Animals; Arrhythmias, Cardiac; Chick Embryo; Dose-Response Relationship | 1986 |
Triploidy 69, XXX in a stillborn girl.
Topics: Adult; Asthma; Chromatids; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-1 | 1973 |