phenobarbital has been researched along with Intradural-Extramedullary Spinal Cord Neoplasms in 2 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this investigation was to determine whether paraplegia induced by neoplastic cord compression affects the pharmacodynamics of phenobarbital general anesthesia or of pentylenetetrazol (PTZ)-induced convulsions." | 7.69 | Pharmacodynamics of phenobarbital anesthesia and pentylenetetrazol-induced maximal seizures in a rat model of neoplastic spinal cord compression. ( Alfon, J; Hoffman, A; Siegal, T, 1994) |
| "The purpose of this investigation was to determine whether paraplegia induced by neoplastic cord compression affects the pharmacodynamics of phenobarbital general anesthesia or of pentylenetetrazol (PTZ)-induced convulsions." | 3.69 | Pharmacodynamics of phenobarbital anesthesia and pentylenetetrazol-induced maximal seizures in a rat model of neoplastic spinal cord compression. ( Alfon, J; Hoffman, A; Siegal, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoffman, A | 1 |
| Alfon, J | 1 |
| Siegal, T | 2 |
| White, SJ | 1 |
| McLean, AE | 1 |
| Howland, C | 1 |
2 other studies available for phenobarbital and Intradural-Extramedullary Spinal Cord Neoplasms
| Article | Year |
|---|---|
Pharmacodynamics of phenobarbital anesthesia and pentylenetetrazol-induced maximal seizures in a rat model of neoplastic spinal cord compression.
Topics: Anesthesia; Animals; Histiocytoma, Benign Fibrous; Male; Paraplegia; Pentylenetetrazole; Phenobarbit | 1994 |
Anticonvulsant drugs and cancer. A cohort study in patients with severe epilepsy.
Topics: Adolescent; Adult; Brain Neoplasms; Child; England; Epilepsy; Female; Follow-Up Studies; Humans; Mal | 1979 |