phenobarbital has been researched along with Insulin Resistance in 2 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A change in insulin sensitivity is possibly involved." | 1.27 | Phenobarbital treatment enhances insulin mediated glucose metabolism in man. ( Lahtela, JT; Särkkä, P; Sotaniemi, EA, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Kort, S | 1 |
| Keszthelyi, D | 1 |
| Masclee, AA | 1 |
| Lahtela, JT | 1 |
| Särkkä, P | 1 |
| Sotaniemi, EA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Innate and Adaptive Immunity After Acute Myocardial Infarction BATTLE-AMI Study (B And T Types of Lymphocytes Evaluation in Acute Myocardial Infarction)[NCT02428374] | Phase 4 | 300 participants (Anticipated) | Interventional | 2015-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for phenobarbital and Insulin Resistance
| Article | Year |
|---|---|
Leaky gut and diabetes mellitus: what is the link?
Topics: Animals; Cholera Toxin; Cytokines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diet; Hapto | 2011 |
1 other study available for phenobarbital and Insulin Resistance
| Article | Year |
|---|---|
Phenobarbital treatment enhances insulin mediated glucose metabolism in man.
Topics: Adult; Blood Glucose; Female; Humans; Insulin; Insulin Resistance; Lactates; Lactic Acid; Male; Meta | 1984 |