phenobarbital has been researched along with Infantile Respiratory Distress Syndrome in 13 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 11-month-old boy with multiple surface anomalies and respiratory distress due to upper airway narrowing developed generalized tonic seizures coinciding with apnea." | 7.73 | [High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome]. ( Hayashi, T; Horio, K; Kubota, M; Mimaki, M; Tomita, S, 2006) |
| "An 11-month-old boy with multiple surface anomalies and respiratory distress due to upper airway narrowing developed generalized tonic seizures coinciding with apnea." | 3.73 | [High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome]. ( Hayashi, T; Horio, K; Kubota, M; Mimaki, M; Tomita, S, 2006) |
| " Therefore phenobarbitone does not have seem to have any significant effect on cerebral haemodynamics up to a dosage of 20 mg/kg, so that there is no apparent effect on the risk of cerebral haemorrhage." | 2.66 | [Doppler flow velocities in cerebral arteries in relation to intravenous phenobarbital in premature infants weighing between 500 and 1,500 g]. ( Jorch, G; Michel, E; Rabe, H; Rickers, E; Stöhr, G; Süllwald, A, 1988) |
| "Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition." | 1.46 | A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017) |
| "Phenobarbital levels were higher in symptomatic infants than asymptomatic infants, although the difference was not statistically significant." | 1.37 | Infants born to mothers under phenobarbital treatment: correlation between serum levels and clinical features of neonates. ( Antichi, E; Cardiello, V; Carducci, C; Catenazzi, P; D'Antuono, A; Piras, A; Pozzoli, G; Romagnoli, C; Scorrano, A; Zuppa, AA, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, LE | 1 |
| Hutchison, LB | 1 |
| Hornik, CD | 1 |
| Smith, PB | 1 |
| Cotten, CM | 1 |
| Bidegain, M | 1 |
| Zuppa, AA | 1 |
| Carducci, C | 1 |
| Scorrano, A | 1 |
| Antichi, E | 1 |
| Catenazzi, P | 1 |
| Piras, A | 1 |
| Pozzoli, G | 1 |
| Cardiello, V | 1 |
| D'Antuono, A | 1 |
| Romagnoli, C | 1 |
| Hayashi, T | 1 |
| Kubota, M | 1 |
| Mimaki, M | 1 |
| Tomita, S | 1 |
| Horio, K | 1 |
| Wimberley, PD | 1 |
| Lou, HC | 1 |
| Pedersen, H | 1 |
| Hejl, M | 1 |
| Lassen, NA | 1 |
| Friis-Hansen, B | 4 |
| Glade, G | 1 |
| Saccar, CL | 1 |
| Pereira, GR | 1 |
| Leviton, A | 1 |
| Kuban, KC | 1 |
| Pagano, M | 1 |
| Allred, EN | 1 |
| Van Marter, L | 1 |
| Koh, KS | 1 |
| Andersen, G | 1 |
| Faerø, O | 2 |
| Osler, M | 2 |
| Trolle, D | 2 |
| Vargas, GC | 1 |
| Pildes, RS | 1 |
| Vidyasagar, D | 1 |
| Keith, LG | 1 |
| Jorch, G | 1 |
| Rickers, E | 1 |
| Rabe, H | 1 |
| Stöhr, G | 1 |
| Süllwald, A | 1 |
| Michel, E | 1 |
| Morales, WJ | 1 |
| Koerten, J | 1 |
1 review available for phenobarbital and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Premature labour.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Albuterol; Amnion; Anti-Bacterial Agents; Bacteri | 1976 |
3 trials available for phenobarbital and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
Antenatal corticosteroids appear to reduce the risk of postnatal germinal matrix hemorrhage in intubated low birth weight newborns.
Topics: Cerebral Hemorrhage; Glucocorticoids; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Pre | 1993 |
[Doppler flow velocities in cerebral arteries in relation to intravenous phenobarbital in premature infants weighing between 500 and 1,500 g].
Topics: Birth Weight; Blood Flow Velocity; Cerebrovascular Circulation; Echoencephalography; Humans; Infant, | 1988 |
Prevention of intraventricular hemorrhage in very low birth weight infants by maternally administered phenobarbital.
Topics: Administration, Oral; Cerebral Hemorrhage; Female; Fetal Monitoring; Fetal Organ Maturity; Humans; I | 1986 |
9 other studies available for phenobarbital and Infantile Respiratory Distress Syndrome
| Article | Year |
|---|---|
A case of infant delirium in the neonatal intensive care unit.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid | 2017 |
Infants born to mothers under phenobarbital treatment: correlation between serum levels and clinical features of neonates.
Topics: Adult; Anticonvulsants; Cohort Studies; Epilepsy; Female; Hospitals, University; Humans; Infant, New | 2011 |
[High-dose phenobarbital therapy is effective for the control of intractable tonic seizure with apnea in a case of multiple anomalies syndrome].
Topics: Abnormalities, Multiple; Anticonvulsants; Apnea; Cough; Humans; Infant, Newborn; Male; Phenobarbital | 2006 |
Hypertensive peaks in the pathogenesis of intraventricular hemorrhage in the newborn. Abolition by phenobarbitone sedation.
Topics: Blood Pressure; Cerebral Hemorrhage; Female; Humans; Hypertension; Infant, Newborn; Infant, Prematur | 1982 |
Cimetidine in pregnancy: apparent transient liver impairment in the newborn.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cimetidine; Fema | 1980 |
Hypercholesterolemia in the newborn: occurrence after anterpartum treatment with betamethasone-phenobarbital-ritodrine for the prevention of the respiratory distress syndrome.
Topics: Betamethasone; Cholesterol; Female; Humans; Hypercholesterolemia; Infant, Newborn; Infant, Newborn, | 1978 |
Antepartum glucocorticoid therapy combined with phenobarbitone and ritodrine for prevention of respiratory distress syndrome (RDS) in pre-term infants.
Topics: Betamethasone; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Infant Mortality; Infant, | 1979 |
Prevention of the respiratory distress syndrome (RDS) by antepartum glucocorticoid (betamethasone) therapy combined with phenobarbitone and ritodrine.
Topics: Betamethasone; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Obstetric Labor, Prematur | 1978 |
Effect of maternal heroin addiction on 67 liveborn neonates. Withdrawal symptoms, small body size, and small head circumference were frequent findings.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Birth Weight; Blood Glucose; Cephalomet | 1975 |