Page last updated: 2024-11-02

phenobarbital and Inappropriate ADH Syndrome

phenobarbital has been researched along with Inappropriate ADH Syndrome in 3 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Inappropriate ADH Syndrome: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.

Research Excerpts

ExcerptRelevanceReference
"A lidocaine level was obtained at 4 h post-ingestion and was 0."5.28Rapid onset of seizures following aspiration of viscous lidocaine. ( Garrettson, LK; McGee, EB, 1992)
" We describe a patient with phenobarbital-induced hypersensitivity syndrome who revealed syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with limbic encephalitis during the course of the disease."3.74Syndrome of inappropriate secretion of antidiuretic hormone associated with limbic encephalitis in a patient with drug-induced hypersensitivity syndrome. ( Fukuhara, M; Kano, Y; Sakuma, K; Shiohara, T, 2008)
"A lidocaine level was obtained at 4 h post-ingestion and was 0."1.28Rapid onset of seizures following aspiration of viscous lidocaine. ( Garrettson, LK; McGee, EB, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sakuma, K1
Kano, Y1
Fukuhara, M1
Shiohara, T1
Garrettson, LK1
McGee, EB1
Ishida, C1
Kakehashi, H1
Kusunoki, Y1
Sakata, H1
Takimoto, M1
Yoshioka, H1

Other Studies

3 other studies available for phenobarbital and Inappropriate ADH Syndrome

ArticleYear
Syndrome of inappropriate secretion of antidiuretic hormone associated with limbic encephalitis in a patient with drug-induced hypersensitivity syndrome.
    Clinical and experimental dermatology, 2008, Volume: 33, Issue:3

    Topics: Acyclovir; Aged; Anticonvulsants; Antiviral Agents; Coma; Drug Hypersensitivity; Encephalitis; Epile

2008
Rapid onset of seizures following aspiration of viscous lidocaine.
    Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:3

    Topics: Drainage, Postural; Extracorporeal Membrane Oxygenation; Female; Humans; Inappropriate ADH Syndrome;

1992
Acute phenobarbital intoxication in an infant.
    Acta paediatrica Japonica : Overseas edition, 1990, Volume: 32, Issue:3

    Topics: Acute Disease; Humans; Inappropriate ADH Syndrome; Infant; Male; Phenobarbital

1990