phenobarbital has been researched along with Idiopathic Parkinson Disease in 8 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rotenone is a mitochondrial toxin which can produce Parkinson syndrome (PS) in rats." | 1.33 | Increased myocardial N-myristoyltransferase activity in rotenone model of Parkinsonism. ( Pasha, MK; Rajput, AH; Sharma, RK, 2005) |
| "Essential tremor is a common disorder whose aetiology is unknown." | 1.27 | Essential tremor. ( Findley, LJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ONUAGULUCHI, G | 1 |
| Pasha, MK | 1 |
| Sharma, RK | 1 |
| Rajput, AH | 1 |
| Marchand, L | 1 |
| Schobben, F | 1 |
| van der Kleijn, E | 1 |
| Gabreëls, FJ | 1 |
| Clarke, BM | 1 |
| Upton, A | 1 |
| Griffin, H | 1 |
| Hudoba, P | 1 |
| Findley, LJ | 1 |
| Knopp, W | 1 |
| Porot, M | 1 |
| Petit, G | 1 |
| Couadau, A | 1 |
| Bosson, P | 1 |
1 trial available for phenobarbital and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Psychiatric changes in patients treated with levodopa. I. The clinical experiment.
Topics: Activities of Daily Living; Adjustment Disorders; Aged; Amitriptyline; Clinical Trials as Topic; Dia | 1970 |
7 other studies available for phenobarbital and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
Drug therapy in the crises of postencephalitic parkinsonism.
Topics: Amobarbital; Encephalitis; Encephalitis, Arbovirus; Humans; Parkinson Disease; Parkinson Disease, Po | 1961 |
Increased myocardial N-myristoyltransferase activity in rotenone model of Parkinsonism.
Topics: Acyl Coenzyme A; Aminophylline; Animals; Atropine; Disease Models, Animal; Drug Combinations; Humans | 2005 |
[Treatment of essential tremor].
Topics: Anti-Anxiety Agents; Anti-Dyskinesia Agents; Botulinum Toxins; Humans; Hypnotics and Sedatives; Meth | 1995 |
Pharmacokinetics of di-n-propylacetate in epileptic patients.
Topics: Administration, Oral; Aged; Body Weight; Child; Child, Preschool; Dose-Response Relationship, Drug; | 1975 |
Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
Topics: Adult; Carbamazepine; Cognition; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Humans; Male | 1991 |
Essential tremor.
Topics: Diagnosis, Differential; Humans; Parkinson Disease; Phenobarbital; Phenylethylmalonamide; Primidone; | 1986 |
[Clinical tests of C.E. 10010 in tremor and abnormal movements].
Topics: Adult; Aged; Humans; Middle Aged; Movement Disorders; Parkinson Disease; Phenobarbital; Tremor | 1968 |