phenobarbital has been researched along with Hypothermia, Accidental in 26 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This article presents an additional case of concomitant topiramate and phenobarbital administration that resulted in 8 hospital admissions for hypothermia that resolved after discontinuation of phenobarbital." | 7.91 | Recurrent Admissions for Hypothermia From Concomitant Topiramate and Phenobarbital: A Case Report. ( Mutch, AM, 2019) |
| "Pretreatment of mice with phenobarbital, an inducer of oxidative drug metabolism, had no effect on the early hypothermic effect of a toxic dose of acetaminophen, while pretreatment with metyrapone, SKF-525A, or piperonyl butoxide (inhibitors of mixed-function oxidase) enhanced the hypothermia." | 7.66 | Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound. ( Massey, TE; McElligott, TF; Racz, WJ; Walker, RM, 1982) |
| "Seizures are common in infants with HIE undergoing TH and may worsen outcome." | 5.48 | The effects of adding prophylactic phenobarbital to therapeutic hypothermia in the term-equivalent hypoxic-ischemic rat. ( Aronowitz, E; Hutton, A; Krishna, S; Moore, H; Vannucci, SJ, 2018) |
| "This article presents an additional case of concomitant topiramate and phenobarbital administration that resulted in 8 hospital admissions for hypothermia that resolved after discontinuation of phenobarbital." | 3.91 | Recurrent Admissions for Hypothermia From Concomitant Topiramate and Phenobarbital: A Case Report. ( Mutch, AM, 2019) |
| "Hypothermia induced by LY 300164 combined with VPA may be useful in various central nervous system disease treatments." | 3.72 | Is a hypothermic effect of LY300164, valproate and phenobarbital evident in mice? ( Czuczwar, SJ; Luszczki, JJ; Swiader, MJ; Wielosz, M; Wierzchowska-Cioch, E; Zwolan, A, 2004) |
| "Pretreatment of mice with phenobarbital, an inducer of oxidative drug metabolism, had no effect on the early hypothermic effect of a toxic dose of acetaminophen, while pretreatment with metyrapone, SKF-525A, or piperonyl butoxide (inhibitors of mixed-function oxidase) enhanced the hypothermia." | 3.66 | Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound. ( Massey, TE; McElligott, TF; Racz, WJ; Walker, RM, 1982) |
| "Seizures are common in infants with HIE undergoing TH and may worsen outcome." | 1.48 | The effects of adding prophylactic phenobarbital to therapeutic hypothermia in the term-equivalent hypoxic-ischemic rat. ( Aronowitz, E; Hutton, A; Krishna, S; Moore, H; Vannucci, SJ, 2018) |
| "Hypothermia was associated with a decreased number of circulating PMNs but did not increase the number of neurologically intact survivors." | 1.27 | Influence of hypothermia, barbiturate therapy, and intracranial pressure monitoring on morbidity and mortality after near-drowning. ( Barker, GA; Biggar, WD; Bohn, DJ; Conn, AW; Smith, CR, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (69.23) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 2 (7.69) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Ikonomidou, C | 1 |
| Wang, SH | 1 |
| Fuhler, NA | 1 |
| Larson, S | 1 |
| Capuano, S | 1 |
| Brunner, KR | 1 |
| Crosno, K | 1 |
| Simmons, HA | 1 |
| Mejia, AF | 1 |
| Noguchi, KK | 1 |
| Deshpande, P | 1 |
| Jain, A | 1 |
| McNamara, PJ | 1 |
| Krishna, S | 1 |
| Hutton, A | 1 |
| Aronowitz, E | 1 |
| Moore, H | 1 |
| Vannucci, SJ | 1 |
| Mutch, AM | 1 |
| MACH, Z | 1 |
| TOCZYSKI, T | 1 |
| ZYGULSKAMACHOWA, H | 1 |
| SZILAGYI, T | 1 |
| BENKO, K | 1 |
| CSERNYANSZKY, H | 1 |
| GESSA, GL | 1 |
| VARGIU, L | 1 |
| FROMMEL, E | 1 |
| FLEURY, C | 1 |
| VON LEDEBUR, I | 1 |
| BEGUIN, M | 1 |
| SVANES, K | 1 |
| Swiader, MJ | 1 |
| Luszczki, JJ | 1 |
| Zwolan, A | 1 |
| Wierzchowska-Cioch, E | 1 |
| Wielosz, M | 1 |
| Czuczwar, SJ | 1 |
| Narimatsu, S | 1 |
| Yamamoto, I | 1 |
| Watanabe, K | 1 |
| Yoshimura, H | 1 |
| Kadar, D | 1 |
| Tang, BK | 1 |
| Conn, AW | 2 |
| Massey, TE | 1 |
| Walker, RM | 1 |
| McElligott, TF | 1 |
| Racz, WJ | 1 |
| Ali, SF | 1 |
| Newport, RR | 1 |
| Holson, W | 1 |
| Slikker, W | 1 |
| Bowyer, JF | 1 |
| Hantson, P | 1 |
| Ziade, D | 1 |
| Evenepoel, M | 1 |
| Mahieu, P | 1 |
| Commissaris, RL | 1 |
| Ardayfio, PA | 1 |
| McQueen, DA | 1 |
| Gilchrist, GA | 1 |
| Overstreet, DH | 1 |
| Wing, DR | 1 |
| Paton, WD | 1 |
| Bohn, DJ | 1 |
| Biggar, WD | 1 |
| Smith, CR | 1 |
| Barker, GA | 1 |
| Ponessa, JT | 1 |
| De Boer, B | 1 |
| Franko, BV | 1 |
| Ward, JW | 1 |
| Gilbert, DL | 1 |
| Woodard, G | 1 |
| Maehle, BO | 1 |
| Carmichael, SW | 1 |
| Dey, PK | 1 |
| Mukherjee, A | 1 |
| Stanfield, JP | 1 |
| Buchel, L | 1 |
| Liblau, L | 1 |
| Murawsky, M | 1 |
| Prioux-Guyonneau, M | 1 |
| Meyer, HJ | 1 |
| Dierstein, M | 1 |
26 other studies available for phenobarbital and Hypothermia, Accidental
| Article | Year |
|---|---|
Mild hypothermia fails to protect infant macaques from brain injury caused by prolonged exposure to Antiseizure drugs.
Topics: Animals; Brain; Brain Injuries; Humans; Hypothermia; Hypothermia, Induced; Infant; Infant, Newborn; | 2022 |
Effect of Phenobarbitone on Amplitude-Integrated Electroencephalography in Neonates with Hypoxic-Ischemic Encephalopathy during Hypothermia.
Topics: Adolescent; Electroencephalography; Humans; Hypothermia; Hypothermia, Induced; Hypoxia-Ischemia, Bra | 2020 |
The effects of adding prophylactic phenobarbital to therapeutic hypothermia in the term-equivalent hypoxic-ischemic rat.
Topics: Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Brain Injuries; Disease Models, Animal | 2018 |
Recurrent Admissions for Hypothermia From Concomitant Topiramate and Phenobarbital: A Case Report.
Topics: Anticonvulsants; Drug Interactions; Epilepsy; Female; Hospitalization; Humans; Hypothermia; Middle A | 2019 |
[Iodine metabolism in hypothermia].
Topics: Hypothermia; Iodides; Iodine; Phenobarbital | 1957 |
[Study of electric impulses in hypothermia during largactil or luminal treatment].
Topics: Chlorpromazine; Electricity; Hypothermia; Phenobarbital | 1958 |
[Diuretic activity of chlorothiazide. III. Potentiation of reserpine-induced hypothermia by chlorothiazide].
Topics: Acetazolamide; Chlorothiazide; Diuretics; Hypothermia; Hypothermia, Induced; Phenobarbital; Reserpin | 1959 |
[Deviations in the pharmacodynamic action of various drugs by hypo- and hyperthermia. 2].
Topics: Acetylcholine; Aminobutyrates; Amphetamine; Amphetamines; Atropine; Chlordiazepoxide; Chlorpromazine | 1962 |
STUDIES IN HYPOTHERMIA. II. THE INFLUENCE OF DEEP HYPOTHERMIA ON THE FORMATION OF FLUID EXUDATE IN ACUTE INFLAMMATION IN MICE.
Topics: Anesthesia; Anesthesia, Intravenous; Anesthesiology; Animals; Body Fluids; Capillary Permeability; E | 1964 |
Is a hypothermic effect of LY300164, valproate and phenobarbital evident in mice?
Topics: Animals; Anticonvulsants; Benzodiazepines; Body Temperature; Drug Therapy, Combination; Female; Hypo | 2004 |
9 alpha, 10 alpha-epoxyhexahydrocannabinol formation from delta 9-tetrahydrocannabinol by liver microsomes of phenobarbital-treated mice and its pharmacological activities in mice.
Topics: Animals; Anticonvulsants; Catalepsy; Dronabinol; Humans; Hypothermia; Male; Mice; Microsomes, Liver; | 1983 |
The fate of phenobarbitone in children in hypothermia and at normal body temperature.
Topics: Adolescent; Age Factors; Body Temperature; Body Weight; Child; Child, Preschool; Furosemide; Glucuro | 1982 |
Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound.
Topics: Acetaminophen; Animals; Hypothermia; Male; Mice; Phenobarbital; Piperonyl Butoxide; Proadifen; Time | 1982 |
Low environmental temperatures or pharmacologic agents that produce hyperthermia decrease methamphetamine neurotoxicity in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cold Temperature; Corpus Striatum; Dizocilpine Maleate; Dop | 1995 |
Severe hypoxia and hypothermia following barbiturate poisoning.
Topics: Hemodynamics; Humans; Hypnotics and Sedatives; Hypothermia; Hypoxia; Male; Middle Aged; Phenobarbita | 1996 |
Conflict behavior and the effects of 8-OHDPAT treatment in rats selectively bred for differential 5-HT(1A)-induced hypothermia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Conflict, Psychological; Dose- | 2000 |
Effects of acute delta1-tetrahydrocannabinol treatment, of hypothermia and of ambient temperature on choline incorporation into mouse brain.
Topics: Animals; Brain; Choline; Dronabinol; Hypothermia; Male; Mice; Motor Activity; Phenobarbital; Tempera | 1979 |
Influence of hypothermia, barbiturate therapy, and intracranial pressure monitoring on morbidity and mortality after near-drowning.
Topics: Adolescent; Child; Child, Preschool; Drowning; Humans; Hypothermia; Hypothermia, Induced; Infant; In | 1986 |
The effect of reserpine and syrosingopine upon pentobarbital depression.
Topics: Animals; Blood Pressure; Body Temperature; Central Nervous System; Drug Synergism; Hypotension; Hypo | 1966 |
Toxicologic studies of glycopyrrolate in combination with other drugs.
Topics: Animals; Ataxia; Body Weight; Carbamates; Catechols; Dogs; Feeding Behavior; Female; Glycopyrrolate; | 1971 |
[A case of periodic hypothermia].
Topics: Cerebral Ventricles; Cerebral Ventriculography; Humans; Hypothermia; Male; Middle Aged; Nose Disease | 1973 |
Fluorescence microscopy of the adrenal medulla of the newborn puppy after asphyxia and hypothermia.
Topics: Adrenal Medulla; Anesthesia, General; Anesthesia, Local; Animals; Animals, Newborn; Asphyxia; Borohy | 1974 |
Responses of the circulatory system towards the vasoactive drugs in hypothermia under different anesthesia.
Topics: Acetylcholine; Anesthesia; Animals; Blood Circulation; Cats; Epinephrine; Ergonovine; Heart; Histami | 1967 |
Fever in children in the tropics.
Topics: Anti-Bacterial Agents; Aspirin; Child; Child, Preschool; Chloroquine; Fever; Humans; Hypothermia; Ph | 1969 |
[Influence of pyschotropic substances on variations of total plasma free fatty acids in constrained rats].
Topics: Animals; Chlorpromazine; Depression, Chemical; Dextromoramide; Fatty Acids, Nonesterified; Female; H | 1969 |
[On the antagonistic effect of pyrone compounds of the kava rhizome (Piper methysticum Forst) against 1,4-dipyrrolidino-2-butyne].
Topics: Alkynes; Animals; Atropine; Chlorpromazine; Drug Antagonism; Drug Synergism; Hypothermia; Male; Mice | 1965 |