phenobarbital has been researched along with Hypotension in 21 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared propofol with high-dose barbiturates in the treatment of refractory status epilepticus (RSE) and propose a protocol for the administration of propofol in RSE in adults, correlating propofol's effect with plasma levels." | 9.08 | Treatment of refractory status epilepticus with propofol: clinical and pharmacokinetic findings. ( Dulaney, E; Kramer, TH; O'Meeghan, R; Raps, EC; Skaar, DJ; Stecker, MM, 1998) |
| "Phenobarbital sodium (PhS) has been used in anticonvulsant concentrations in premature newborns in attempts to prevent peri- and intraventricular hemorrhages (PIVH)." | 5.29 | Phenobarbital and cerebral blood flow during hypotension in newborn pigs. ( Contant, CF; Goddard-Finegold, J; Martin, CG; Michael, LH; Yamashita, Y, 1993) |
| "We compared propofol with high-dose barbiturates in the treatment of refractory status epilepticus (RSE) and propose a protocol for the administration of propofol in RSE in adults, correlating propofol's effect with plasma levels." | 5.08 | Treatment of refractory status epilepticus with propofol: clinical and pharmacokinetic findings. ( Dulaney, E; Kramer, TH; O'Meeghan, R; Raps, EC; Skaar, DJ; Stecker, MM, 1998) |
| "Pentobarbital is standard treatment for refractory status epilepticus (SE) and is almost uniformly effective, but the morbidity of treatment and the mortality of refractory SE are high." | 3.69 | Relapse and survival after barbiturate anesthetic treatment of refractory status epilepticus. ( Drislane, FW; Krishnamurthy, KB, 1996) |
| "Enuresis is a common problem often treated effectively with imipramine hydrochloride." | 3.66 | Treatment of imipramine overdose in children. ( Cromie, WJ; Greene, AS, 1981) |
| "Phenobarbital has been shown to be an effective adjunctive therapy for AWS, reducing benzodiazepine use, in the emergency department." | 1.56 | Phenobarbital and symptom-triggered lorazepam versus lorazepam alone for severe alcohol withdrawal in the intensive care unit. ( Lam, SW; Nguyen, TA, 2020) |
| "Phenobarbital sodium (PhS) has been used in anticonvulsant concentrations in premature newborns in attempts to prevent peri- and intraventricular hemorrhages (PIVH)." | 1.29 | Phenobarbital and cerebral blood flow during hypotension in newborn pigs. ( Contant, CF; Goddard-Finegold, J; Martin, CG; Michael, LH; Yamashita, Y, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (71.43) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Staidle, A | 1 |
| Geier, C | 1 |
| Nguyen, TA | 1 |
| Lam, SW | 1 |
| KROGSGAARD, AR | 2 |
| KFOGSGAARD, AR | 1 |
| MEDVEDEV, Ia | 1 |
| ROVINA, AK | 1 |
| OSTAPENKO, GI | 1 |
| SEKIYA, A | 1 |
| VAUGHANWILLIAMS, EM | 1 |
| Lal, R | 1 |
| Faiz, S | 1 |
| Garg, RK | 1 |
| Baweja, KS | 1 |
| Guntupalli, J | 1 |
| Finkel, KW | 1 |
| Griffith, PA | 1 |
| Karp, HR | 1 |
| Greene, AS | 1 |
| Cromie, WJ | 1 |
| Yamashita, Y | 1 |
| Goddard-Finegold, J | 1 |
| Contant, CF | 1 |
| Martin, CG | 1 |
| Michael, LH | 1 |
| Krishnamurthy, KB | 1 |
| Drislane, FW | 1 |
| Stecker, MM | 1 |
| Kramer, TH | 1 |
| Raps, EC | 1 |
| O'Meeghan, R | 1 |
| Dulaney, E | 1 |
| Skaar, DJ | 1 |
| Boldyrev, AI | 1 |
| Fleĭs, EP | 1 |
| Vaĭntrub, MIa | 1 |
| Diehl, LW | 1 |
| Bosl, R | 1 |
| Shideman, JR | 1 |
| Meyer, RM | 1 |
| Buselmeier, TJ | 1 |
| von Hartitzsch, B | 1 |
| Kjellstrand, CM | 1 |
| López, C | 1 |
| Jiménez, W | 1 |
| Arroyo, V | 1 |
| La Villa, G | 1 |
| Gaya, J | 1 |
| Clària, J | 1 |
| Rivera, F | 1 |
| Rodés, J | 1 |
| Tsueda, K | 1 |
| Jean-Francois, J | 1 |
| Richter, RW | 1 |
| Ponessa, JT | 1 |
| De Boer, B | 1 |
| Sheffer, AL | 1 |
| Bell, DS | 1 |
| Nilsson, L | 1 |
1 trial available for phenobarbital and Hypotension
| Article | Year |
|---|---|
Treatment of refractory status epilepticus with propofol: clinical and pharmacokinetic findings.
Topics: Adult; Aged; Barbiturates; Clinical Protocols; Drug Administration Schedule; Drug Therapy, Combinati | 1998 |
20 other studies available for phenobarbital and Hypotension
| Article | Year |
|---|---|
Phenobarbital and/or benzodiazepines for recurrent alcohol withdrawal: A self-controlled, retrospective cohort study.
Topics: Alcoholism; Benzodiazepines; Humans; Hypotension; Phenobarbital; Retrospective Studies; Substance Wi | 2022 |
Phenobarbital and symptom-triggered lorazepam versus lorazepam alone for severe alcohol withdrawal in the intensive care unit.
Topics: Adult; Aged; Alcoholism; Central Nervous System Agents; Drug Therapy, Combination; Ethanol; Female; | 2020 |
[Effect of reserpine in lowering blood pressure compared with phenemal and placebo; preliminary study].
Topics: Blood Pressure; Blood Pressure Determination; Humans; Hypotension; Phenobarbital; Reserpine | 1956 |
[Effect of reserpine in lowering blood pressure compared with phenemal and placebo; preliminary study].
Topics: Blood Pressure; Blood Pressure Determination; Humans; Hypotension; Phenobarbital; Reserpine | 1956 |
[Effect of reserpine in lowering blood pressure compared with phenemal and placebo; preliminary study].
Topics: Blood Pressure; Blood Pressure Determination; Humans; Hypotension; Phenobarbital; Reserpine | 1956 |
[Effect of reserpine in lowering blood pressure compared with phenemal and placebo; preliminary study].
Topics: Blood Pressure; Blood Pressure Determination; Humans; Hypotension; Phenobarbital; Reserpine | 1956 |
Hypotensive effect of reserpine compared with phenobarbital and placebo.
Topics: Humans; Hypertension; Hypotension; Phenobarbital; Reserpine | 1957 |
[ANESTHESIA IN OPERATIONS FOR AORTIC COARCTATION].
Topics: Adolescent; Anesthesia; Anesthesia, Intravenous; Aortic Coarctation; Blood Transfusion; Child; Elect | 1964 |
CENTRAL AND PERIPHRAL ACTIONS OF PRONETHALOL.
Topics: Arrhythmias, Cardiac; Blood Pressure; Chloroform; Electrocardiography; Epinephrine; Ethanolamines; E | 1965 |
Use of continuous venovenous hemodiafiltration in a case of severe phenobarbital poisoning.
Topics: Coma; Drug Overdose; Hemodiafiltration; Humans; Hypnotics and Sedatives; Hypotension; Male; Middle A | 2006 |
Lorazepam in therapy for status epilepticus.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Apnea; Drug Therapy, Combination; Humans; Hypotension; Loraz | 1980 |
Treatment of imipramine overdose in children.
Topics: Adult; Arrhythmias, Cardiac; Bicarbonates; Child; Child, Preschool; Coma; Diazepam; Drug Administrat | 1981 |
Phenobarbital and cerebral blood flow during hypotension in newborn pigs.
Topics: Animals; Animals, Newborn; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Circulation; Hypoten | 1993 |
Relapse and survival after barbiturate anesthetic treatment of refractory status epilepticus.
Topics: Adult; Anesthetics, Intravenous; Electroencephalography; Humans; Hypotension; Infusions, Intravenous | 1996 |
[Neurologic complications following medical treatment of epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Ataxia; Benzodiazepines; Consciousness Disorders; Dysarthria; Ey | 1979 |
[Anticonvulsants and simultaneous medication - a problem in pregnancy (author's transl)].
Topics: Adult; Anticonvulsants; Antiemetics; Dihydroergotamine; Drug Combinations; Drug Interactions; Drug T | 1977 |
Effects and complications of high efficiency dialysis.
Topics: Barbiturates; Blood Urea Nitrogen; Body Weight; Calcium; Creatinine; Edema; Headache; Humans; Hypote | 1975 |
Role of altered systemic hemodynamics in the blunted renal response to atrial natriuretic peptide in rats with cirrhosis and ascites.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Hemodynamics; Hypotension; Infus | 1989 |
Cardiac standstill in tetanus: review of seven consecutive cases.
Topics: Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Heart Arrest; Heroin Dependence; Humans; H | 1973 |
The effect of reserpine and syrosingopine upon pentobarbital depression.
Topics: Animals; Blood Pressure; Body Temperature; Central Nervous System; Drug Synergism; Hypotension; Hypo | 1966 |
Treatment of anaphylaxis.
Topics: Anaphylaxis; Desensitization, Immunologic; Diphenhydramine; Drug Hypersensitivity; Ephedrine; Epinep | 1973 |
Dangers of treatment of status epilepticus with diazepam.
Topics: Adolescent; Adult; Aged; Cheyne-Stokes Respiration; Child; Diazepam; Drug Antagonism; Epilepsies, Pa | 1969 |
The influence of barbiturate anaesthesia upon the energy state and upon acid-base parameters of the brain in arterial hypotension and in asphyxia.
Topics: Acid-Base Equilibrium; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Anest | 1971 |