phenobarbital has been researched along with Hypospadias in 1 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Hypospadias: A birth defect due to malformation of the URETHRA in which the urethral opening is below its normal location. In the male, the malformed urethra generally opens on the ventral surface of the PENIS or on the PERINEUM. In the female, the malformed urethral opening is in the VAGINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three families are described in which each of the mothers took trimethadione during pregnancy." | 7.65 | The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975) |
| "Three families are described in which each of the mothers took trimethadione during pregnancy." | 3.65 | The fetal trimethadione syndrome. ( Hanson, JW; Mellman, WJ; Neiderer, B; Zackai, EH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zackai, EH | 1 |
| Mellman, WJ | 1 |
| Neiderer, B | 1 |
| Hanson, JW | 1 |
1 other study available for phenobarbital and Hypospadias
| Article | Year |
|---|---|
The fetal trimethadione syndrome.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Anthropometry; Child, Preschool; Developmental | 1975 |