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phenobarbital and Hypoglycemia

phenobarbital has been researched along with Hypoglycemia in 23 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.

Research Excerpts

ExcerptRelevanceReference
"In two children treated for hypoglycemia and convulsions with diazoxide and diphenylhydantoin, therapeutic serum diphenylhydantoin levels were not achieved despite doses of diphenylhydantoin of 17 and 29 mg/kg/day, respectively."3.65Drug interaction: diazoxide and diphenylhydantoin. ( Blaskovics, ME; Podosin, RL; Roe, TF, 1975)
"Malaria is a major problem in children in many parts of Papua New Guinea; it has a high mortality and, if observations from other countries are applicable, significant long-term morbidity."2.38Malaria in children in Papua New Guinea. ( Vince, JD, 1992)
"Febrile seizures are a common problem."2.37Febrile seizures: emergency department diagnosis and treatment. ( Ater, SB; Bettis, DB, 1985)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199019 (82.61)18.7374
1990's2 (8.70)18.2507
2000's1 (4.35)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moore, AR1
Chu, C1
Singh, K1
Barger, AM1
Schnelle, AN1
STOIMENOV, I1
LOLOVA, Kh1
NEWILL, RG1
Stola, A1
Perlman, J1
Ajaya, B1
Haranath, PS1
Halberstadt, E1
Gerner, R1
Walker, W1
Holden, KR1
Freeman, JM2
Roe, TF1
Podosin, RL1
Blaskovics, ME1
Vince, JD1
Karvonen, I1
Sormunen, R1
Huupponen, R1
Sotaniemi, EA1
Bettis, DB1
Ater, SB1
Vining, EP1
Fox, GR1
Virgo, BB1
Lennox-Buchthal, MA1
Buist, NR1
Campbell, JR1
Castro, A1
Saad, SF1
Josephson, DA1
Volpe, J1
Thaler, MM1
Ballow, M1
Margolis, CZ1
Schachtel, B1
Hsia, YE1
Knott, DH1
Beard, JD1
Verma, IC1
Bhasin, V1

Reviews

8 reviews available for phenobarbital and Hypoglycemia

ArticleYear
Post-resuscitation strategies to avoid ongoing injury following intrapartum hypoxia-ischemia.
    Seminars in fetal & neonatal medicine, 2008, Volume: 13, Issue:6

    Topics: Anticonvulsants; Blood Pressure; Female; Fetal Hypoxia; Fluid Therapy; Humans; Hyperglycemia; Hypogl

2008
Haemolytic anaemia in the newborn infant.
    Clinics in haematology, 1975, Volume: 4, Issue:1

    Topics: ABO Blood-Group System; Amniocentesis; Antibodies; Blood Group Incompatibility; Blood Transfusion, I

1975
Neonatal seizures and their treatment.
    Clinics in perinatology, 1975, Volume: 2, Issue:1

    Topics: Anticonvulsants; Diazepam; Humans; Hypocalcemia; Hypoglycemia; Infant, Newborn; Infant, Newborn, Dis

1975
Malaria in children in Papua New Guinea.
    Papua and New Guinea medical journal, 1992, Volume: 35, Issue:4

    Topics: Antimalarials; Cause of Death; Child; Child Welfare; Child, Preschool; Clinical Protocols; Communica

1992
Febrile seizures: emergency department diagnosis and treatment.
    The Journal of emergency medicine, 1985, Volume: 2, Issue:5

    Topics: Blood Cell Count; Blood Glucose; Child, Preschool; Counseling; Diagnosis, Differential; Diazepam; Dr

1985
Seizures which are not epilepsy.
    Pediatric annals, 1985, Volume: 14, Issue:11

    Topics: Child, Preschool; Epilepsies, Partial; Fever; Humans; Hypocalcemia; Hypoglycemia; Infant; Infant, Ne

1985
Febrile convulsions. A reappraisal.
    Electroencephalography and clinical neurophysiology, 1973, Volume: 32

    Topics: Age Factors; Animals; Animals, Newborn; Body Temperature; Brain; Brain Damage, Chronic; Child, Presc

1973
Neonatal Seizures.
    The New England journal of medicine, 1973, Aug-23, Volume: 289, Issue:8

    Topics: Birth Injuries; Calcium; Congenital Abnormalities; Glucose; Humans; Hypocalcemia; Hypoglycemia; Infa

1973

Other Studies

15 other studies available for phenobarbital and Hypoglycemia

ArticleYear
What is your diagnosis? Liver aspirate from a hypoglycemic dog.
    Veterinary clinical pathology, 2015, Volume: 44, Issue:3

    Topics: Abdomen; Animals; Anticonvulsants; Biopsy, Fine-Needle; Dog Diseases; Dogs; Euthanasia, Animal; Hypo

2015
[Hypoglycemic coma induced by small doses of insulin in the treatment of psychiatric diseases; combination of insulin with luminal and caffeine. I].
    Suvremenna meditsina, 1957, Volume: 8, Issue:10

    Topics: Caffeine; Coma; Convulsive Therapy; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Mental Disor

1957
NOCTURNAL EPILEPSY AND HYPOGLYCAEMIA.
    The Practitioner, 1964, Volume: 193

    Topics: Anticonvulsants; Child; Circadian Rhythm; Delayed-Action Preparations; Drug Therapy; Electroencephal

1964
Effects of insulin administered into cerebrospinal fluid spaces on blood glucose in unanaesthetized and anaesthetized dogs.
    The Indian journal of medical research, 1982, Volume: 75

    Topics: Anesthesia; Animals; Blood Glucose; Brain; Cats; Dogs; Hyperglycemia; Hypoglycemia; Injections, Intr

1982
[Biochemical maturation of organs in the foetus and its induction (author's transl)].
    Zeitschrift fur Geburtshilfe und Perinatologie, 1979, Volume: 183, Issue:1

    Topics: Adaptation, Physiological; Enzyme Induction; Female; Fetus; Glucocorticoids; Humans; Hyaline Membran

1979
Drug interaction: diazoxide and diphenylhydantoin.
    The Journal of pediatrics, 1975, Volume: 87, Issue:3

    Topics: Administration, Oral; Adolescent; Child, Preschool; Chromatography, Gas; Diazoxide; Drug Therapy, Co

1975
Reduced glucose-6-phosphorylase and NADPH generating enzyme activities associated with glibenclamide induced hypoglycemia and hypoinsulinemia in genetically obese mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1990, Volume: 44, Issue:6

    Topics: Animals; Antiporters; Endoplasmic Reticulum; Female; Glucosephosphate Dehydrogenase; Glyburide; Hypo

1990
The effects of phenobarbital, atropine, L-alpha-methyldopa, and DL-propranolol on dieldrin-induced hyperglycemia in the adult rat.
    Toxicology and applied pharmacology, 1985, Volume: 78, Issue:3

    Topics: Administration, Oral; Animals; Atropine; Blood Glucose; Central Nervous System; Dieldrin; Drug Inter

1985
Congenital islet cell adenoma causing hypoglycemia in a newborn.
    Pediatrics, 1971, Volume: 47, Issue:3

    Topics: Adenoma, Islet Cell; Blood Glucose; Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Infant, Ne

1971
The effect of isoniazid and some anticonvulsant drugs on the gamma-aminobutyric acid content of mouse brain in insulin hypoglycaemia.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:5

    Topics: Aminobutyrates; Animals; Barbiturates; Brain; Brain Chemistry; Cerebral Cortex; Hypoglycemia; Insuli

1970
Status epilepticus.
    American family physician, 1974, Volume: 10, Issue:4

    Topics: Diazepam; Epilepsy; Humans; Hypocalcemia; Hypoglycemia; Magnesium Deficiency; Paraldehyde; Phenobarb

1974
Neonatal hyperbilirubinemia.
    Seminars in hematology, 1972, Volume: 9, Issue:2

    Topics: Acidosis; Agar; Anemia, Hemolytic; Antibodies; Bilirubin; Blood Group Incompatibility; Blood Transfu

1972
Progressive familial intrahepatic cholestasis.
    Pediatrics, 1973, Volume: 51, Issue:6

    Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts, Intrahepatic; C

1973
Diagnosis and therapy of acute withdrawal from alcohol.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Acute Disease; Adult; Alcoholism; Anti-Bacterial Agents; Anticonvulsants; Carbohydrate Metabolism; C

1970
Seizures in infancy due to idiopathic hypoglycemia. Report of a case.
    Indian journal of pediatrics, 1970, Volume: 37, Issue:268

    Topics: Fasting; Glucose; Humans; Hypoglycemia; Infant; Male; Phenobarbital; Seizures

1970