phenobarbital has been researched along with Hypertrichosis in 3 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Hypertrichosis: Excessive hair growth at inappropriate locations, such as on the extremities, the head, and the back. It is caused by genetic or acquired factors, and is an androgen-independent process. This concept does not include HIRSUTISM which is an androgen-dependent excess hair growth in WOMEN and CHILDREN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Phenytoin, on the other hand, causes gingival hyperplasia in many patients, irreversible hypertrichosis in some patients and lethal reactions, such as Stevens-Johnson syndrome, in a few patients." | 3.66 | Phenobarbital vs. phenytoin for grand mal epilepsy. ( Kramer, II; Livingston, S; Pauli, LL; Pruce, I, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Domenici, R | 1 |
| Giovannucci Uzielli, ML | 1 |
| Castelli, S | 1 |
| Livingston, S | 2 |
| Pauli, LL | 1 |
| Pruce, I | 1 |
| Kramer, II | 1 |
3 other studies available for phenobarbital and Hypertrichosis
| Article | Year |
|---|---|
[Multiple-abnormalities syndrome with phenotypic characteristics falling within the lacrimo-auriculo-dento-digital syndrome].
Topics: Abnormalities, Drug-Induced; Ear, External; Female; Growth Disorders; Hand Deformities, Congenital; | 1984 |
Phenobarbital vs. phenytoin for grand mal epilepsy.
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; Epi | 1980 |
Treatment of grand mal epilepsy: phenobarbital versus diphenylhydantoin sodium.
Topics: Adolescent; Epilepsy, Tonic-Clonic; Female; Gingival Hyperplasia; Humans; Hypertrichosis; Infant; Ph | 1968 |