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phenobarbital and Hypernatremia

phenobarbital has been researched along with Hypernatremia in 5 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Hypernatremia: Excessive amount of sodium in the blood. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" Sorbitol, another osmotic cathartic commonly used in the treatment of drug intoxications, has been reported in the pediatric literature to induce severe hypernatremia, but there is only a rare case report in an adult."7.68Hypernatremia due to repeated doses of charcoal-sorbitol. ( Allerton, JP; Strom, JA, 1991)
" Sorbitol, another osmotic cathartic commonly used in the treatment of drug intoxications, has been reported in the pediatric literature to induce severe hypernatremia, but there is only a rare case report in an adult."3.68Hypernatremia due to repeated doses of charcoal-sorbitol. ( Allerton, JP; Strom, JA, 1991)
"Most had had a convulsion before admission."1.26Dexamethasone in the treatment of hypernatraemic dehydration. ( Haque, KN, 1981)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WONG, LC1
HEIMBACH, MD1
TRUSCOTT, DR1
DUNCAN, BD1
Haque, KN1
Banister, A1
Matin-Siddiqi, SA1
Hatcher, GW1
Allerton, JP1
Strom, JA1
Shaywitz, BA1

Other Studies

5 other studies available for phenobarbital and Hypernatremia

ArticleYear
BORIC ACID POISONING: REPORT OF 11 CASES.
    Canadian Medical Association journal, 1964, Apr-25, Volume: 90

    Topics: Acidosis; Anti-Bacterial Agents; Borates; Boric Acids; Color Perception Tests; Dehydration; Diarrhea

1964
Dexamethasone in the treatment of hypernatraemic dehydration.
    Archives of disease in childhood, 1981, Volume: 56, Issue:3

    Topics: Blood Glucose; Calcium; Dehydration; Dexamethasone; Humans; Hypernatremia; Infant; Phenobarbital; Se

1981
Treatment of hypernatraemic dehydration in infancy.
    Archives of disease in childhood, 1975, Volume: 50, Issue:3

    Topics: Bicarbonates; Body Weight; Dehydration; Gastroenteritis; Humans; Hyperglycemia; Hypernatremia; Hypoc

1975
Hypernatremia due to repeated doses of charcoal-sorbitol.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 17, Issue:5

    Topics: Adult; Cathartics; Charcoal; Female; Humans; Hypernatremia; Phenobarbital; Poisoning; Sorbitol; Susp

1991
Extreme elevations of cerebrospinal fluid protein. Association with hypernatremic dehydration.
    American journal of diseases of children (1960), 1970, Volume: 120, Issue:1

    Topics: Blood Proteins; Blood-Brain Barrier; Central Nervous System Diseases; Cerebrospinal Fluid Proteins;

1970