phenobarbital has been researched along with Hyperhomocysteinemia in 3 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hyperhomocysteinemia was defined as fasting total Hcy above 12 micromol/L and/or post-methionine load concentrations above 38 micromol/L." | 3.74 | Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins. ( Apeland, T; Frøyland, ES; Kristensen, O; Mansoor, MA; Strandjord, RE, 2008) |
| "Our data indicate that not only fasting but also 6h-PML tHcy levels should be determined in order to identify hyperhomocysteinemia among patients on AEDs." | 3.70 | Homocysteine concentrations and methionine loading in patients on antiepileptic drugs. ( Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Apeland, T | 2 |
| Frøyland, ES | 1 |
| Kristensen, O | 2 |
| Strandjord, RE | 2 |
| Mansoor, MA | 2 |
| Belcastro, V | 1 |
| Striano, P | 1 |
| Gorgone, G | 1 |
| Costa, C | 1 |
| Ciampa, C | 1 |
| Caccamo, D | 1 |
| Pisani, LR | 1 |
| Oteri, G | 1 |
| Marciani, MG | 1 |
| Aguglia, U | 1 |
| Striano, S | 1 |
| Ientile, R | 1 |
| Calabresi, P | 1 |
| Pisani, F | 1 |
3 other studies available for phenobarbital and Hyperhomocysteinemia
| Article | Year |
|---|---|
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; | 2008 |
Hyperhomocysteinemia in epileptic patients on new antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Enzyme Induction; Epilepsy; Female; Folic Acid; F | 2010 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; E | 2000 |