phenobarbital has been researched along with Hypercholesterolemia in 8 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of dietary taurine on endogenous hypercholesterolemia induced by a phenobarbital-containing diet was investigated." | 7.70 | Effect of dietary taurine on endogenous hypercholesterolemia in rats fed on phenobarbital-containing diets. ( Mochizuki, H; Takido, J; Yokogoshi, H, 1999) |
| "The effect of dietary taurine on endogenous hypercholesterolemia induced by a phenobarbital-containing diet was investigated." | 3.70 | Effect of dietary taurine on endogenous hypercholesterolemia in rats fed on phenobarbital-containing diets. ( Mochizuki, H; Takido, J; Yokogoshi, H, 1999) |
| " Sequential addition of cholestyramine and phenobarbital to his medical regimen, following an initial response to bile drainage, resulted in the disappearance of xanthomas and pruritus, and the restoration of normal serum concentrations of lipids and bile acids." | 3.65 | Immunodeficiency, xanthomas and obstructive liver disease. ( Hanson, RF; Isenberg, JN; Page, AR; Sharp, HL; Williams, GC; Zavoral, J, 1976) |
| "Phenobarbital treatment increased liver weight and mean hepatocyte volume by 39 and 26%, respectively, while total DNA content did not change, thus indicating that the hepatomegaly results principally from hypertrophy rather than hyperplasia." | 1.27 | Bile acid secretion and pool size during phenobarbital induced hypercholeresis. ( Alpini, G; Berk, PD; Jones, MJ; Kiang, CL; Okuda, H; Sorrentino, D; Tavoloni, N, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cozzi, P | 1 |
| Branzoli, U | 1 |
| Lovisolo, PP | 1 |
| Orsini, G | 1 |
| Carganico, G | 1 |
| Pillan, A | 1 |
| Chiari, A | 1 |
| Mochizuki, H | 1 |
| Takido, J | 1 |
| Yokogoshi, H | 1 |
| Yilmaz, E | 1 |
| Doşan, Y | 1 |
| Gürgöze, MK | 1 |
| Güngör, S | 1 |
| Andersen, G | 1 |
| Friis-Hansen, B | 1 |
| Byers, SO | 1 |
| Friedman, M | 1 |
| Brunner, G | 1 |
| Isenberg, JN | 1 |
| Hanson, RF | 1 |
| Williams, GC | 1 |
| Zavoral, J | 1 |
| Page, AR | 1 |
| Sharp, HL | 1 |
| Okuda, H | 1 |
| Sorrentino, D | 1 |
| Alpini, G | 1 |
| Tavoloni, N | 1 |
| Jones, MJ | 1 |
| Kiang, CL | 1 |
| Berk, PD | 1 |
8 other studies available for phenobarbital and Hypercholesterolemia
| Article | Year |
|---|---|
N-imidazolylchroman-4-ones, N-imidazolyl-1-tetralones, and their alcohols as hypolipemic agents raising high-density lipoproteins.
Topics: Alcohols; Animals; Cholesterol; Enzyme Induction; Hypercholesterolemia; Hypolipidemic Agents; Imidaz | 1986 |
Effect of dietary taurine on endogenous hypercholesterolemia in rats fed on phenobarbital-containing diets.
Topics: Animals; Bile Acids and Salts; Body Weight; Cholesterol; Diet; Drug Interactions; Eating; Feces; Hyp | 1999 |
Serum lipid changes during anticonvulsive treatment serum lipids in epileptic children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cholesterol; Cholesterol, HDL; | 2001 |
Hypercholesterolemia in the newborn: occurrence after anterpartum treatment with betamethasone-phenobarbital-ritodrine for the prevention of the respiratory distress syndrome.
Topics: Betamethasone; Cholesterol; Female; Humans; Hypercholesterolemia; Infant, Newborn; Infant, Newborn, | 1978 |
Phenobarbital as a hypocholesterolemic agent in the rat and rabbit.
Topics: Animals; Anticholesteremic Agents; Barbital; Bile; Bile Acids and Salts; Cholesterol; Hexobarbital; | 1976 |
[Therapy of the chronic destructive, non-purulent cholangitis (primary biliary cirrhosis)].
Topics: Azathioprine; Calcium; Cholangitis; Cholestyramine Resin; Clofibrate; Humans; Hypercholesterolemia; | 1976 |
Immunodeficiency, xanthomas and obstructive liver disease.
Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Child; Cholestyramine Resin; Cholic Acids; Humans; Hype | 1976 |
Bile acid secretion and pool size during phenobarbital induced hypercholeresis.
Topics: Animals; Bile Acids and Salts; Body Weight; DNA; Hypercholesterolemia; Kinetics; Liver; Male; Organ | 1988 |