phenobarbital has been researched along with Hyperbilirubinemia, Hereditary in 83 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Hyperbilirubinemia, Hereditary: Inborn errors of bilirubin metabolism resulting in excessive amounts of bilirubin in the circulating blood, either because of increased bilirubin production or because of delayed clearance of bilirubin from the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of phenobarbital treatment on bilirubin metabolism and bile secretion was studied in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis." | 7.66 | Effect of phenobarbital on serum and biliary parameters in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis. ( Malet, PF; Rosato, EF; Roy-Chowdhury, J; Shaw, L; Trotman, BW, 1983) |
| "Sodium phenobarbital and various hormones, compounds capable of hepatic enzyme induction, were given to an infant boy with congenital, nonhemolytic, unconjugated, hyperbilirubinemia and severe kernicterus for prolonged periods between the ages of 2 and 25 months to determine their effect on serum bilirubin concentrations." | 7.65 | Effect of sodium phenobarbital on bilirubin metabolism in an infant with congenital, nonhemolytic, unconjugated hyperbilirubinemia, and kernicterus. ( Crigler, JF; Gold, NI, 1969) |
| "The effect of phenobarbital treatment on bilirubin metabolism and bile secretion was studied in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis." | 3.66 | Effect of phenobarbital on serum and biliary parameters in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis. ( Malet, PF; Rosato, EF; Roy-Chowdhury, J; Shaw, L; Trotman, BW, 1983) |
| "An oral tolerance test using a 25-mg dose of ursodeoxycholic acid was carried out in 46 patients with constitutional hyperbilirubinemias: 26 with Gilbert's syndrome, 9 with Dubin-Johnson syndrome, 7 with Rotor Syndrome, 3 with constitutional indocyanine green intolerance, and 1 with Crigler-Najjar syndrome type II; they were compared with 14 healthy control subjects." | 3.66 | Ursodeoxycholic acid oral tolerance test in patients with constitutional hyperbilirubinemias and effect of phenobarbital. ( Iida, S; Makino, I; Ohkubo, H; Okuda, K, 1981) |
| "Sodium phenobarbital and various hormones, compounds capable of hepatic enzyme induction, were given to an infant boy with congenital, nonhemolytic, unconjugated, hyperbilirubinemia and severe kernicterus for prolonged periods between the ages of 2 and 25 months to determine their effect on serum bilirubin concentrations." | 3.65 | Effect of sodium phenobarbital on bilirubin metabolism in an infant with congenital, nonhemolytic, unconjugated hyperbilirubinemia, and kernicterus. ( Crigler, JF; Gold, NI, 1969) |
| "The recognition that Gilbert's syndrome is a quite heterogeneous entity will allow a better understanding of the mode of inheritance of this disorder; its relationship to Crigler-Najjar type II disease also awaits further definition." | 1.27 | Familial unconjugated hyperbilirubinemia syndromes. ( Reichen, J, 1983) |
| "Phenobarbital treatment resulted in significant increases in serum GGT activity (p less than 0." | 1.26 | Effects of phenobarbital on unconjugated bilirubin clearance, gamma-glutamyltranspeptidase and urinary d-glucaric acid in patients with Gilbert's syndrome. ( Hirayama, C; Kawasaki, H; Kimura, N; Murawaki, Y, 1982) |
| "Phenobarbital treatment significantly reduced the level of unconjugated serum bilirubin in patients with acute hepatitis or Gilbert's syndrome, but without any difference within these two groups of patients." | 1.26 | Diagnosis of Gilbert's syndrome. Reliability of the caloric restriction and phenobarbital stimulation tests. ( Hardt, F; Juhl, E; Thomsen, HF, 1981) |
| "The pathophysiology of Gilbert's syndrome was studied by investigating the metabolism of the drug tolbutamide, which is metabolised by the liver but does not undergo glucuronidation." | 1.26 | Alteration of drug metabolism in Gilbert's syndrome. ( Carulli, N; Ferrari, A; Manenti, F; Mauro, E; Ponz de Leon, M, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 81 (97.59) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (2.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Garg, PK | 1 |
| Kumar, A | 1 |
| Teckchandani, N | 1 |
| Hadke, NS | 1 |
| Maruo, Y | 1 |
| Topaloglu, AK | 1 |
| Takahashi, H | 1 |
| Mori, A | 1 |
| Iwai, M | 1 |
| Duzovali, O | 1 |
| Yamamoto, K | 1 |
| Matui, K | 1 |
| Sato, H | 1 |
| Takeuchi, Y | 1 |
| Robinson, SH | 1 |
| Lester, R | 1 |
| Crigler, JF | 3 |
| Tsong, M | 1 |
| Kawasaki, H | 2 |
| Murawaki, Y | 1 |
| Kimura, N | 1 |
| Hirayama, C | 2 |
| Narang, AP | 1 |
| Datta, DV | 1 |
| Reichen, J | 1 |
| Trotman, BW | 1 |
| Shaw, L | 1 |
| Roy-Chowdhury, J | 1 |
| Malet, PF | 1 |
| Rosato, EF | 1 |
| Cruz, NS | 1 |
| Alváez, RG | 1 |
| Trelles, JB | 1 |
| Ohkubo, H | 1 |
| Okuda, K | 1 |
| Iida, S | 1 |
| Makino, I | 1 |
| Iwańczak, F | 1 |
| Prandota, J | 1 |
| Thomsen, HF | 1 |
| Hardt, F | 1 |
| Juhl, E | 1 |
| Plöchl, E | 1 |
| Hohenwallner, W | 1 |
| Breckenridge, A | 2 |
| Wehinger, H | 1 |
| Goresky, CA | 1 |
| Gordon, ER | 1 |
| Shaffer, EA | 1 |
| Paré, P | 1 |
| Carassavas, D | 1 |
| Aronoff, A | 1 |
| Johnson, JD | 1 |
| Gollan, JL | 2 |
| Huang, SN | 2 |
| Billing, B | 1 |
| Sherlock, S | 3 |
| Lovisetto, P | 2 |
| Giorcelli, W | 2 |
| Actis, GC | 2 |
| Biarese, V | 2 |
| Kirshenbaum, G | 1 |
| Shames, DM | 1 |
| Schmid, R | 2 |
| Carulli, N | 1 |
| Ponz de Leon, M | 1 |
| Mauro, E | 1 |
| Manenti, F | 1 |
| Ferrari, A | 1 |
| Arrowsmith, WA | 1 |
| Payne, RB | 1 |
| Littlewood, JM | 1 |
| Windorfer, A | 2 |
| Eselev, MM | 1 |
| Stsepuro, PG | 1 |
| Pett, S | 1 |
| Mowat, AP | 1 |
| Gentile, S | 1 |
| Del Vecchio Blanco, C | 1 |
| Persico, M | 1 |
| Marmo, R | 1 |
| Coltorti, M | 2 |
| Duhamel, G | 1 |
| Blanckaert, N | 1 |
| Metreau, JM | 1 |
| Préaux, AM | 1 |
| Bouvry, M | 1 |
| Fevery, J | 2 |
| Berthelot, P | 2 |
| Di Simone, A | 1 |
| Di Cesare, D | 1 |
| Rinaldi, M | 1 |
| Thompson, RP | 3 |
| Stathers, GM | 1 |
| Pilcher, CW | 1 |
| McLean, AE | 1 |
| Black, M | 5 |
| Maxwell, JD | 2 |
| Hunter, J | 3 |
| Stewart, DA | 2 |
| Carrella, M | 2 |
| Williams, R | 4 |
| Parker, D | 1 |
| Jacobson, J | 1 |
| Billing, BH | 2 |
| Carson, ER | 1 |
| Bitto, T | 2 |
| Mirabile, V | 1 |
| Tornaghi, GC | 1 |
| Del Ninno, E | 3 |
| Chiesa, G | 1 |
| Portaleone, D | 1 |
| Ideo, G | 2 |
| Orme, ML | 1 |
| Davies, L | 1 |
| Catz, C | 1 |
| Wilson, JT | 1 |
| Lüders, D | 1 |
| Scheig, R | 1 |
| Tornaghi, G | 1 |
| Tripodi, A | 1 |
| Colombo, M | 2 |
| Rosanelli, K | 1 |
| Fromke, VL | 1 |
| Miller, D | 1 |
| Juszczyk, J | 1 |
| Török, J | 1 |
| Eriksson, M | 1 |
| Yaffe, SJ | 1 |
| Götze, H | 1 |
| Sidiropoulos, D | 1 |
| Hess, FA | 1 |
| De Franchis, R | 1 |
| Singh, I | 1 |
| Sharma, NN | 1 |
| Seth, HN | 1 |
| Hunter, JO | 1 |
| Dunn, PM | 1 |
| Felsher, BF | 2 |
| Craig, JR | 1 |
| Carpio, N | 1 |
| Walker, AC | 1 |
| Walker-Smith, JA | 1 |
| Blaschke, TF | 1 |
| Berk, PD | 2 |
| Scharschmidt, BF | 1 |
| Guyther, JR | 1 |
| Vergalla, JM | 1 |
| Waggoner, JG | 1 |
| Arias, IM | 3 |
| Gartner, LM | 3 |
| Cohen, M | 2 |
| Ezzer, JB | 1 |
| Levi, AJ | 2 |
| Rake, MO | 1 |
| Thaler, MM | 1 |
| Bloomer, JR | 1 |
| Howe, RB | 1 |
| Berlin, NI | 1 |
| Harris, RC | 1 |
| Del Rio, A | 1 |
| Noya, M | 1 |
| De Oya, JC | 1 |
| Jakovljev, D | 1 |
| Cvetković, P | 1 |
| Janković, I | 1 |
| Panich, V | 1 |
| Sungnate, T | 1 |
| Pootrakul, P | 1 |
| Schellong, G | 1 |
| Soennecken, U | 1 |
| Vaisman, S | 1 |
| Galecio, R | 1 |
| Erazo, R | 1 |
| Kunzack, H | 1 |
| Kline, W | 1 |
| Rosenkranz, A | 1 |
| Severi, F | 1 |
| Marchi, A | 1 |
| Colombo, A | 1 |
| Billng, BH | 1 |
| Ciampolini, M | 1 |
| Karon, M | 1 |
| Imach, D | 1 |
| Schwartz, A | 1 |
| Specchia, G | 1 |
| Rickard, D | 1 |
| Redeker, AG | 1 |
| Rizzi, D | 1 |
| Pettinati, G | 1 |
| Serio, G | 1 |
| L'Abbate, M | 1 |
| Sakai, K | 1 |
| Irisa, T | 1 |
| Amagase, H | 1 |
| Levy, G | 1 |
| Ertel, IJ | 2 |
| Ben-Ezzer, J | 1 |
| Rubino, A | 1 |
| Barbieri, A | 1 |
| Pierro, M | 1 |
| Gold, NI | 1 |
| Lucey, JF | 1 |
| Newton, WA | 1 |
14 reviews available for phenobarbital and Hyperbilirubinemia, Hereditary
| Article | Year |
|---|---|
Clinical implications of enzyme induction.
Topics: Animals; Barbiturates; Bile; Bilirubin; Digitoxin; Enzyme Induction; gamma-Glutamyltransferase; Gluc | 1975 |
[Congenital nonhemolytic hyperbilirubinemias].
Topics: Adolescent; Adult; Age Factors; Bilirubin; Child; Child, Preschool; Cholestasis; Chronic Disease; Cr | 1977 |
Neonatal nonhemolytic jaundice.
Topics: Bile Acids and Salts; Bile Ducts; Biliary Tract Diseases; Bilirubin; Brain Damage, Chronic; Breast F | 1975 |
The yellow baby.
Topics: Adolescent; Amniocentesis; Animals; Barbiturates; Bile; Bilirubin; Blood Transfusion, Intrauterine; | 1974 |
Developmental pharmacology: a review of its application to clinical and basic science.
Topics: Aging; Androgens; Aniline Compounds; Animals; Estrogens; Ethanol; Female; Fetus; Fluorosis, Dental; | 1972 |
[The pros and cons of luminal teatment of hyperbilirubinemia].
Topics: Adrenocorticotropic Hormone; Animals; Bilirubin; Central Nervous System; Cholesterol; Drug Eruptions | 1970 |
Constitutional hepatic dysfunction (CHD; Gilbert's disease); a review with special reference to a characteristic increase and prolongation of the hyperbilirubinemic response to nicotinic acid.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Anemia, Hemolytic, Congenital; Bilirubin; Fe | 1972 |
[Effects of drugs and other biological and physical factors on bilirubin metabolism in man].
Topics: Animals; Antigens, Bacterial; Bilirubin; Depression, Chemical; Enzyme Induction; Fasting; Female; Fe | 1973 |
[Hyperbilirubinemia in premature infants during 1948-1973 (evaluation and therapy of physiological jaundice in newborn infants of low birth weight during the past 25 years)].
Topics: Adrenal Cortex Hormones; Birth Weight; Brain Diseases; Exchange Transfusion, Whole Blood; Gestationa | 1973 |
Drug metabolism in the newborn.
Topics: Animals; Animals, Newborn; Enzyme Induction; Fetus; Humans; Hyperbilirubinemia; Hyperbilirubinemia, | 1973 |
[Stimulation of the microsomal enzyme system as a therapeutic principle in the newborn infant].
Topics: Anticonvulsants; Blood Coagulation Disorders; Enzyme Induction; Female; Humans; Hyperbilirubinemia, | 1974 |
Chronic nonhemolytic unconjugated hyperbilirubinemia with glucuronyl transferase deficiency. Clinical, biochemical, pharmacologic and genetic evidence for heterogeneity.
Topics: Adolescent; Adult; Bile; Bile Pigments; Bilirubin; Child, Preschool; Female; Genes, Dominant; Genoty | 1969 |
Drugs and bilirubin.
Topics: Adult; Animals; Aspirin; Bile Acids and Salts; Bilirubin; Biological Transport; Biotransformation; E | 1971 |
The newer hyperbilirubinemias.
Topics: ABO Blood-Group System; Anemia, Hemolytic; Antigen-Antibody Reactions; Bilirubin; Biological Transpo | 1968 |
5 trials available for phenobarbital and Hyperbilirubinemia, Hereditary
| Article | Year |
|---|---|
Comparison of in-vivo and in-vitro drug metabolism in patients with Gilbert's syndrome.
Topics: Adult; Antipyrine; Bilirubin; Clinical Trials as Topic; Female; Gilbert Disease; Humans; Hyperbiliru | 1982 |
[The use of optimal doses of phenobarbital in the treatment of Gilbert's syndrome].
Topics: Adult; Clinical Trials as Topic; Female; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Ma | 1988 |
[Current problems in the hyperbilirubinemia of premature infants].
Topics: Bilirubin; Birth Weight; Clinical Trials as Topic; Enzyme Induction; Humans; Hyperbilirubinemia, Her | 1972 |
Controlled trial of phetharbital, a non-hypnotic barbiturate, in unconugated hyperbilirubinaemia.
Topics: Abdomen; Barbiturates; Bilirubin; Clinical Trials as Topic; Female; Humans; Hyperbilirubinemia, Here | 1971 |
Interpretation of plasma bilirubin levels based on studies with radioactive bilirubin.
Topics: Bilirubin; Carbon Isotopes; Clinical Trials as Topic; Depression, Chemical; Glutethimide; Humans; Hy | 1971 |
64 other studies available for phenobarbital and Hyperbilirubinemia, Hereditary
| Article | Year |
|---|---|
Hereditary spherocytosis coexisting with Gilbert's syndrome: a diagnostic dilemma.
Topics: Adolescent; Bilirubin; Caloric Restriction; Diagnosis, Differential; Gilbert Disease; Humans; Hyperb | 2008 |
Crigler-Najjar syndrome type II caused by a homozygous triple mutation [T-3279G, A(TA)7TAA, and H39D] of UGT1A1.
Topics: Blotting, Western; Child; Crigler-Najjar Syndrome; Gene Expression Regulation, Enzymologic; Genetic | 2006 |
Early-labeled peak of bile pigment in man. Studies with glycine-14C and delta-aminolevulinic acid-3H.
Topics: Adolescent; Bile; Bilirubin; Carbon Isotopes; Glycine; Heme; Hemoglobinometry; Hemoglobins; Humans; | 1967 |
Effects of phenobarbital on unconjugated bilirubin clearance, gamma-glutamyltranspeptidase and urinary d-glucaric acid in patients with Gilbert's syndrome.
Topics: Adult; Bilirubin; Female; gamma-Glutamyltransferase; Gilbert Disease; Glucaric Acid; Humans; Hyperbi | 1982 |
Familial unconjugated hyperbilirubinemia syndromes.
Topics: Animals; Bile Acids and Salts; Bilirubin; Crigler-Najjar Syndrome; Diagnosis, Differential; Disease | 1983 |
Effect of phenobarbital on serum and biliary parameters in a patient with Crigler-Najjar syndrome, type II and acquired cholestasis.
Topics: Adult; Bile; Cholestasis; Crigler-Najjar Syndrome; Humans; Hyperbilirubinemia, Hereditary; Liver Fun | 1983 |
[Gilbert's disease. Presentation of 2 cases].
Topics: Adolescent; Bilirubin; Bone Marrow; Child; Energy Intake; Female; Gilbert Disease; Humans; Hyperbili | 1982 |
Ursodeoxycholic acid oral tolerance test in patients with constitutional hyperbilirubinemias and effect of phenobarbital.
Topics: Administration, Oral; Adult; Deoxycholic Acid; Female; Gilbert Disease; Humans; Hyperbilirubinemia, | 1981 |
[Gilbert's syndrome. Diagnostic difficulties and successful use of the luminal test].
Topics: Adolescent; Bilirubin; Child; Diagnosis, Differential; Female; Gilbert Disease; Humans; Hyperbilirub | 1980 |
Diagnosis of Gilbert's syndrome. Reliability of the caloric restriction and phenobarbital stimulation tests.
Topics: Acute Disease; Adolescent; Adult; Bilirubin; Diagnosis, Differential; Energy Intake; Fasting; Female | 1981 |
[Treatment of Crigler-Najjar's congenital familial non-hemolytic jaundice with kernicterus].
Topics: Crigler-Najjar Syndrome; Developmental Disabilities; Epilepsy; Female; Humans; Hyperbilirubinemia; H | 1978 |
Definition of a conjugation of dysfunction in Gilbert's syndrome: studies of the handling of bilirubin loads and of the pattern of bilirubin conjugates secreted in bile.
Topics: Adolescent; Adult; Bile; Bile Pigments; Bilirubin; Fasting; Female; Gilbert Disease; Humans; Hyperbi | 1978 |
Prolonged survival in three brothers with severe type 2 Crigler-Najjar syndrome. Ultrastructural and metabolic studies.
Topics: Bile Acids and Salts; Bile Pigments; Bilirubin; Crigler-Najjar Syndrome; Electroencephalography; Glu | 1975 |
[Gilbert's jaundice. Current clinico-nosographic, physiopathological and therapeutic aspects. III. Therapeutic action of enzyme inductors with reference to unconjugated bilirubin icterus].
Topics: Adult; Enzyme Induction; Female; Gilbert Disease; Glucuronates; Humans; Hyperbilirubinemia, Heredita | 1977 |
An expanded model of bilirubin kinetics: effect of feeding, fasting, and phenobarbital in Gilbert's syndrome.
Topics: Adult; Bilirubin; Eating; Fasting; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Kinetics | 1976 |
[Gilbert's jaundice. Current clinico-nosographical, physiopathological and therapeutic aspects. Note II. The phenomenon of enzyme induction at the level of the liver].
Topics: Amino Acids; Animals; Enzyme Induction; Gilbert Disease; Humans; Hyperbilirubinemia, Hereditary; Liv | 1976 |
Alteration of drug metabolism in Gilbert's syndrome.
Topics: Adult; Animals; Cytoplasm; Gilbert Disease; Half-Life; Humans; Hyperbilirubinemia, Hereditary; Liver | 1976 |
Comparison of treatments for congenital nonobstructive nonhaemolytic hyperbilirubinaemia.
Topics: Agar; Aspartic Acid; Bilirubin; Brain Damage, Chronic; Child, Preschool; Cholestyramine Resin; Dieta | 1975 |
[New indications for phenobarbital in pediatrics].
Topics: Animals; Child, Preschool; Female; Humans; Hyperbilirubinemia, Hereditary; Infant, Newborn; Microsom | 1975 |
Crigler-Najjar syndrome types I and II. Clinical experience--King's College Hospital 1972-1978. Phenobarbitone, phototherapy and liver transplantation.
Topics: Child; Child, Preschool; Crigler-Najjar Syndrome; Female; Humans; Hyperbilirubinemia, Hereditary; In | 1987 |
Familial clustering of heterogeneous chronic unconjugated hyperbilirubinemia.
Topics: Adult; Child; Chronic Disease; Female; Half-Life; Humans; Hyperbilirubinemia, Hereditary; Male; Midd | 1986 |
An unusual case of Crigler-Najjar disease in the adult. Classification into types I and II revisited.
Topics: Adult; Bile; Bile Acids and Salts; Bilirubin; Crigler-Najjar Syndrome; Glucuronosyltransferase; Huma | 1985 |
Effect of phenobarbital administration on liver and plasma gamma-glutamyl-transpeptidase: clinical and experimental investigations.
Topics: Animals; Body Weight; Chronic Disease; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Induction; ga | 1973 |
Treatment of unconjugated jaundice with dicophane.
Topics: Adolescent; Animals; Bilirubin; Cytochromes; DDT; Enzyme Induction; Glucuronates; Humans; Hyperbilir | 1969 |
Treatment of Gilbert's syndrome with phenobarbitone.
Topics: Adolescent; Adult; Bilirubin; Enzyme Induction; Female; Glucosyltransferases; Glutathione; Humans; H | 1970 |
Effect of phenobarbitone on bile flow and bilirubin metabolism in man and the rat.
Topics: Adipates; Animals; Bile; Bilirubin; Body Weight; Cytochrome P-450 Enzyme System; Enzyme Induction; G | 1973 |
Effect of phenobarbitone on plasma (14C)bilirubin clearance in patients with unconjugated hyperbilirubinaemia.
Topics: Adolescent; Adult; Anemia, Hemolytic; Bilirubin; Carbon Radioisotopes; Child; Female; Glucuronosyltr | 1974 |
[Proceedings: Effect of repeated administration of spironolactone, ethanol and phenobarbital on liver bilirubin UDPG-transferase in Gilbert's jaundice].
Topics: Adolescent; Adult; Bilirubin; Ethanol; Female; Glucuronosyltransferase; Hexosyltransferases; Humans; | 1973 |
Increased glucuronidation of bilirubin in man and rat by administration of antipyrine (phenazone).
Topics: Adolescent; Adult; Animals; Antipyrine; Bilirubin; Glucuronates; Glucuronosyltransferase; Humans; Hy | 1974 |
Neonatal jaundice.
Topics: Albumins; Bile Ducts; Bilirubin; Breast Feeding; Crigler-Najjar Syndrome; Erythroblastosis, Fetal; E | 1974 |
Proceedings: Prolonged survival in the Crigler-Najjar syndrome: ultrastructural and dietary studies.
Topics: Bilirubin; Cell Membrane; Crigler-Najjar Syndrome; Endoplasmic Reticulum; Glucose; Golgi Apparatus; | 1974 |
[The d-glucaric acid test in the evaluation of the inductive properties of phenobarbital and spironalactone].
Topics: Adipates; Adolescent; Adult; Bilirubin; Enzyme Induction; Female; Gilbert Disease; Humans; Hyperbili | 1974 |
[Crigler-Naijar syndrome. Clinical, biochemical, morphologic and therapeutic aspects].
Topics: Bile; Bilirubin; Chromatography, Thin Layer; Clinical Enzyme Tests; Female; Glucuronates; Humans; Hy | 1972 |
[Effect of ethanol and phenobarbital on liver UDPG-transferase and on serum bilirubin in patients with Gilbert's syndrome].
Topics: Adult; Bilirubin; Enzyme Induction; Ethanol; Female; Hexosyltransferases; Humans; Hyperbilirubinemia | 1972 |
Chronic unconjugated non-haemolytic hyperbilirubinaemia--report of a case of Gilbert's disease.
Topics: Adult; Diagnosis, Differential; Hepatitis A; Humans; Hyperbilirubinemia, Hereditary; Male; Phenobarb | 1972 |
Inheritance of type 2 Crigler-Najjar hyperbilirubinaemia.
Topics: Adult; Bilirubin; Female; Genes; Genes, Dominant; Humans; Hyperbilirubinemia, Hereditary; Infant; Ma | 1973 |
Hepatic bilirubin glucuronidation in Gilbert's syndrome.
Topics: Bilirubin; Biopsy; Dietary Carbohydrates; Fasting; Feces; Female; Glucuronidase; Hepatitis A; Humans | 1973 |
Chronic nonhaemolytic unconjugated hyperbilirubinaemia.
Topics: Chronic Disease; Female; Humans; Hyperbilirubinemia, Hereditary; Infant; Infant, Newborn; Phenobarbi | 1973 |
Crigler-Najjar syndrome: an unusual course with development of neurologic damage at age eighteen.
Topics: Adolescent; Alkaline Phosphatase; Bilirubin; Brain Damage, Chronic; Brain Diseases; Carbon Monoxide; | 1974 |
[Phenobarbital treatment of indirect hyperbilirubinemia states in various hepatic diseases].
Topics: Administration, Oral; Hepatitis; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Liver C | 1972 |
[A case of congenital non-hemolytic non-conjugated hyperbilirubinemia treated with phenobarbiton].
Topics: Adolescent; Humans; Hyperbilirubinemia, Hereditary; Male; Phenobarbital | 1972 |
Gilbert's syndrome associated with glucose-6-phosphate dehydrogenase deficiency.
Topics: Adolescent; Adult; Erythrocytes; Glucosephosphate Dehydrogenase Deficiency; Humans; Hyperbilirubinem | 1972 |
[Phenobarbital therapy in congenital nonhemolytic hyperbilirubinemia (Crigler-Najjar)--report of 5 cases].
Topics: Child; Child, Preschool; Endoplasmic Reticulum; Enzyme Induction; Female; Humans; Hyperbilirubinemia | 1971 |
[Hyperbilirubinemia in the newborn and phenobarbital. I. Full term newborn infants].
Topics: Female; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Infant, Newborn; Male; Phenobarb | 1971 |
[Clinical and biochemical studies in the Crigler-Najjar syndrome].
Topics: Bilirubin; Biopsy; Diagnosis, Differential; Enzyme Induction; Female; Humans; Hyperbilirubinemia, He | 1971 |
[Effects of luminal treatment on neonatal hyperbilirubinemia in premature infants].
Topics: Exchange Transfusion, Whole Blood; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Infan | 1971 |
II. Hereditary diseases of pharmacogenetic interest. Pharmacologic and genetic determinants of disordered bilirubin transport and metabolism in the liver.
Topics: Animals; Bilirubin; Glucuronates; Guinea Pigs; Humans; Hyperbilirubinemia, Hereditary; Liver; Liver | 1968 |
The action of drugs on bilirubin metabolism in man.
Topics: Bilirubin; Biopsy; Carbon Isotopes; Cytochromes; Glucuronates; Glutethimide; Humans; Hyperbilirubine | 1971 |
Phenobarbital, hormones, and bilirubin.
Topics: Bilirubin; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Infant, Newborn; Phenobarbita | 1969 |
[Barbiturate therapy of icterus caused by defective bilirubin conjugation].
Topics: Humans; Hyperbilirubinemia, Hereditary; Infant; Male; Phenobarbital | 1969 |
Effective phototherapy in congenital nonobstructive, nonhemolytic jaundice.
Topics: Bilirubin; Glucuronates; Growth; Humans; Hyperbilirubinemia, Hereditary; Infant; Infant, Newborn; Ma | 1970 |
[Action of luminal on non-hemolytic jaundice with indirect bilirubinemia in adults: description of a case].
Topics: Humans; Hyperbilirubinemia, Hereditary; Male; Middle Aged; Phenobarbital | 1970 |
The reciprocal relation between caloric intake and the degree of hyperbilirubinemia in Gilbert's syndrome.
Topics: Adult; Bilirubin; Diet; Fasting; Humans; Hyperbilirubinemia, Hereditary; Phenobarbital; Starvation | 1970 |
The use of phenobarbitone to investigate the pathogenesis of unconjugated hyperbilirubinaemia.
Topics: Bilirubin; Carbon Isotopes; Humans; Hyperbilirubinemia, Hereditary; Phenobarbital | 1970 |
Enzyme induction and bilirubin metabolism.
Topics: Bilirubin; Child; Enzyme Induction; Humans; Hyperbilirubinemia; Hyperbilirubinemia, Hereditary; Phen | 1970 |
[Reduction of indirect bilirubinemia after administration of phenylethylbarbituric acid in non-hemolytic chronic jaundice caused by glycuronyltransferase deficiency].
Topics: Adult; Chronic Disease; Glucuronates; Humans; Hyperbilirubinemia, Hereditary; Jaundice; Male; Metabo | 1970 |
Urinary d-glucaric acid excretion as a measure of hepatic enzyme induction in man.
Topics: Adipates; Anticonvulsants; Barbiturates; Enzyme Induction; Epilepsy; Humans; Hyperbilirubinemia, Her | 1971 |
[Congenital non-hemolytic and non-conjugating-type hyperbilirubinemia].
Topics: Adolescent; Bilirubin; Female; Humans; Hyperbilirubinemia, Hereditary; Indocyanine Green; Iodine Iso | 1971 |
Effect of bilirubin on drug conjugations in children.
Topics: Acetaminophen; Adult; Bilirubin; Biological Transport, Active; Biotransformation; Child; Female; Glu | 1971 |
Chronic nonhemolytic unconjugated hyperbilirubinemia with glucuronyl transferase deficiency: evidence for genetic heterogeneity.
Topics: Adolescent; Adult; Bile; Bilirubin; Child; Child, Preschool; Female; Genes, Dominant; Genes, Recessi | 1968 |
[Therapeutic use of Luminal in Crigler-Najjar type icterus].
Topics: Humans; Hyperbilirubinemia, Hereditary; Infant; Male; Phenobarbital | 1968 |
Effect of sodium phenobarbital on bilirubin metabolism in an infant with congenital, nonhemolytic, unconjugated hyperbilirubinemia, and kernicterus.
Topics: Bilirubin; Carbon Isotopes; Crystallization; Growth Hormone; Humans; Hyperbilirubinemia, Hereditary; | 1969 |
Familial non-hemolytic jaundice: light therapy.
Topics: Fluorescence; Humans; Hyperbilirubinemia, Hereditary; Phenobarbital | 1969 |
Therapy in congenital hyperbilirubinemia: phenobarbital and diethylnicotinamide.
Topics: Bilirubin; Child; Child, Preschool; Female; Humans; Hyperbilirubinemia, Hereditary; Infant; Infant, | 1969 |