Page last updated: 2024-11-02

phenobarbital and Hyperactivity, Motor

phenobarbital has been researched along with Hyperactivity, Motor in 17 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Research Excerpts

ExcerptRelevanceReference
" Phenytoin, on the other hand, causes gingival hyperplasia in many patients, irreversible hypertrichosis in some patients and lethal reactions, such as Stevens-Johnson syndrome, in a few patients."3.66Phenobarbital vs. phenytoin for grand mal epilepsy. ( Kramer, II; Livingston, S; Pauli, LL; Pruce, I, 1980)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199015 (88.24)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bankstahl, M1
Bankstahl, JP1
Löscher, W2
Rattka, M1
Brandt, C1
Levenstein, D1
Gutgesell, ME1
Percy, P1
Livingston, S3
Pauli, LL2
Pruce, I2
Kramer, II1
Livingston, HL1
Stores, G1
Wolf, SM1
Forsythe, A1
Freeman, JM1
Burd, L2
Kerbeshian, J2
Fisher, W2
Gascon, G1
Selye, H1
Szabo, S1
Mécs, I1
Panchenko, EN1
Silbergeld, EK2
Goldberg, AM2
Witzel, K1
Ott, T1
Matthies, H1

Reviews

1 review available for phenobarbital and Hyperactivity, Motor

ArticleYear
Behavioural effects of anti-epileptic drugs.
    Developmental medicine and child neurology, 1975, Volume: 17, Issue:5

    Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Confusion; Disorders of Excess

1975

Other Studies

16 other studies available for phenobarbital and Hyperactivity, Motor

ArticleYear
Inter-individual variation in the anticonvulsant effect of phenobarbital in the pilocarpine rat model of temporal lobe epilepsy.
    Experimental neurology, 2012, Volume: 234, Issue:1

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; E

2012
The intrahippocampal kainate model of temporal lobe epilepsy revisited: epileptogenesis, behavioral and cognitive alterations, pharmacological response, and hippoccampal damage in epileptic rats.
    Epilepsy research, 2013, Volume: 103, Issue:2-3

    Topics: Animals; Anticonvulsants; Cognition Disorders; Disease Models, Animal; Epilepsy, Temporal Lobe; Fema

2013
Phenobarbital side effects: hyperactivity with speech delay.
    Pediatrics, 1984, Volume: 74, Issue:6

    Topics: Child, Preschool; Humans; Hyperkinesis; Infant; Language Development Disorders; Language Disorders;

1984
Phenobarbital vs. phenytoin for grand mal epilepsy.
    American family physician, 1980, Volume: 22, Issue:2

    Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; Epi

1980
The medical treatment of epilepsy: managing side effects of antiepileptic drugs.
    Pediatric annals, 1979, Volume: 8, Issue:4

    Topics: Anticonvulsants; Blood; Cerebellar Ataxia; Child; Child, Preschool; Dextroamphetamine; Drug Eruption

1979
Medical treatment of epilepsy: Part II.
    Southern medical journal, 1978, Volume: 71, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Child; Drug Interactions; Epilepsy; Ep

1978
Behavior disturbance, phenobarbital, and febrile seizures.
    Pediatrics, 1978, Volume: 61, Issue:5

    Topics: Barbiturates; Child Behavior Disorders; Humans; Hyperkinesis; Mephobarbital; Phenobarbital; Recurren

1978
Febrile seizures: an end to confusion.
    Pediatrics, 1978, Volume: 61, Issue:5

    Topics: Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Hyperkinesis; Infant; Infant,

1978
Anticonvulsant medications: an iatrogenic cause of tic disorders.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1986, Volume: 31, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Hyperkinesis; Male; Mephoba

1986
Does the use of phenobarbital as an anticonvulsant permanently exacerbate hyperactivity?
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1987, Volume: 32, Issue:1

    Topics: Diagnosis, Differential; Female; Humans; Hyperkinesis; Male; Phenobarbital

1987
Protection by catatoxic steroids against the paralysis caused by combined treatment with thyroxine and methylphenidate.
    Neuropharmacology, 1972, Volume: 11, Issue:5

    Topics: Androstenols; Animals; Drug Synergism; Estradiol; Ethylestrenol; Female; Humans; Hydroxysteroids; Hy

1972
[Treatment of extrapyramidal hyperkinesis].
    Vrachebnoe delo, 1973, Volume: 7, Issue:7

    Topics: Adolescent; Adult; Ambulatory Care; Basal Ganglia Diseases; Benzimidazoles; Benzyl Compounds; Bromin

1973
Lead-induced behavioral dysfunction: an animal model of hyperactivity.
    Experimental neurology, 1974, Volume: 42, Issue:1

    Topics: Amphetamine; Animals; Chloral Hydrate; Dextroamphetamine; Disease Models, Animal; Female; Humans; Hy

1974
Hyperactivity: a lead-induced behavior disorder.
    Environmental health perspectives, 1974, Volume: 7

    Topics: Amphetamine; Animals; Animals, Newborn; Chloral Hydrate; Diet; Dose-Response Relationship, Drug; Fem

1974
[Paspertin (Metoclopramide) as a cause of dystonic-hyperkinetic syndromes in children].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:2

    Topics: Amides; Benzoates; Biperiden; Child; Diazepam; Female; Gastrointestinal Diseases; Humans; Hyperkines

1972
[Differentiation of neuroleptic and psychosedative effects in screening].
    Acta biologica et medica Germanica, 1969, Volume: 22, Issue:5

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Depression, Chemical; Diazepam; Humans; Hyperkinesis; Hyp

1969