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phenobarbital and Histiocytosis, Langerhans-Cell

phenobarbital has been researched along with Histiocytosis, Langerhans-Cell in 1 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Histiocytosis, Langerhans-Cell: A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.

Research Excerpts

ExcerptRelevanceReference
"The case of a two-year-old girl with generalized histiocytosis, probably induced by phenobarbital, is reported."6.38A case of hypersensitivity syndrome resembling Langerhans cell histiocytosis during phenobarbital prophylaxis for convulsion. ( Kawamura, N; Mino, M; Miyake, M; Motoyama, T; Nagata, T; Oguni, T; Yamasiro, K; Yoden, A; Yoshikawa, K, 1992)
"The case of a two-year-old girl with generalized histiocytosis, probably induced by phenobarbital, is reported."2.38A case of hypersensitivity syndrome resembling Langerhans cell histiocytosis during phenobarbital prophylaxis for convulsion. ( Kawamura, N; Mino, M; Miyake, M; Motoyama, T; Nagata, T; Oguni, T; Yamasiro, K; Yoden, A; Yoshikawa, K, 1992)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagata, T1
Kawamura, N1
Motoyama, T1
Miyake, M1
Yoden, A1
Yoshikawa, K1
Oguni, T1
Yamasiro, K1
Mino, M1

Reviews

1 review available for phenobarbital and Histiocytosis, Langerhans-Cell

ArticleYear
A case of hypersensitivity syndrome resembling Langerhans cell histiocytosis during phenobarbital prophylaxis for convulsion.
    Japanese journal of clinical oncology, 1992, Volume: 22, Issue:6

    Topics: Child, Preschool; Diagnosis, Differential; Drug Eruptions; Eosinophils; Epilepsy; Female; Histiocyte

1992