phenobarbital has been researched along with Hepatitis, Animal in 5 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Hepatitis, Animal: INFLAMMATION of the LIVER in non-human animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital treatment leads to a decrease of the total biliary excretion of metabolites to about 200 microgram/100 g bw/h, the metabolite pattern remaining unchanged." | 5.26 | Alternative transport pathways of cholephilic 14C-hexobarbital metabolites in rats with experimental hepatitis and cholestasis. ( Buschmann, J; Joeres, R; Richter, E; Zilly, W, 1979) |
| "Phenobarbital treatment leads to a decrease of the total biliary excretion of metabolites to about 200 microgram/100 g bw/h, the metabolite pattern remaining unchanged." | 1.26 | Alternative transport pathways of cholephilic 14C-hexobarbital metabolites in rats with experimental hepatitis and cholestasis. ( Buschmann, J; Joeres, R; Richter, E; Zilly, W, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richter, E | 1 |
| Joeres, R | 1 |
| Buschmann, J | 1 |
| Zilly, W | 1 |
| Sugiyama, T | 1 |
| Suzuki, K | 1 |
| Ookawara, T | 1 |
| Kurosawa, T | 1 |
| Taniguchi, N | 1 |
| Budillon, G | 2 |
| Carrella, M | 2 |
| Coltorti, M | 1 |
| De Marco, F | 1 |
| Mazzacca, G | 1 |
| Elek, S | 1 |
| Borsy, J | 1 |
| Maderspach, A | 1 |
| Polgári, I | 1 |
| Osváth, Z | 1 |
| Jámbor, E | 1 |
5 other studies available for phenobarbital and Hepatitis, Animal
| Article | Year |
|---|---|
Alternative transport pathways of cholephilic 14C-hexobarbital metabolites in rats with experimental hepatitis and cholestasis.
Topics: 1-Naphthylisothiocyanate; Animals; Bile; Cholestasis; Chromatography, Thin Layer; Galactosamine; Hep | 1979 |
Selective expression and induction of cytochrome P450PB and P450MC during the development of hereditary hepatitis and hepatoma of LEC rats.
Topics: Age Factors; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Syst | 1989 |
Phenobarbital liver microsomal induction in MHV-3 viral hepatitis of the mouse.
Topics: Aniline Compounds; Animals; Aspartate Aminotransferases; Cytochrome P-450 Enzyme System; Enzyme Indu | 1972 |
Effect of phenobarbital on MHV-3 viral hepatitis of the mouse.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cytochrome P-450 E | 1973 |
[The effect of clofibrate (ethyl-p-chlorophenoxy isobutyrate), M-451 (bis-p-chlorophenoxy-acetylurea) and phenobarbital on experimental liver damage in rats].
Topics: Animals; Carbon Tetrachloride Poisoning; Clofibrate; Cyanates; Ethionine; Hepatitis, Animal; Liver; | 1974 |