phenobarbital has been researched along with Hepatic Porphyria in 4 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, CD | 1 |
| Van Horn, CG | 1 |
| Wan, M | 1 |
| Bishop, C | 1 |
| Bonkovsky, HL | 1 |
| Yasuda, M | 1 |
| Desnick, RJ | 1 |
| Unzu, C | 1 |
| Sampedro, A | 1 |
| Mauleón, I | 1 |
| Alegre, M | 1 |
| Beattie, SG | 1 |
| de Salamanca, RE | 1 |
| Snapper, J | 1 |
| Twisk, J | 1 |
| Petry, H | 1 |
| González-Aseguinolaza, G | 1 |
| Artieda, J | 1 |
| Rodríguez-Pena, MS | 1 |
| Prieto, J | 1 |
| Fontanellas, A | 1 |
| Schuurmans, MM | 1 |
| Hoffmann, F | 1 |
| Lindberg, RL | 1 |
| Meyer, UA | 1 |
1 review available for phenobarbital and Hepatic Porphyria
| Article | Year |
|---|---|
Murine models of the human porphyrias: Contributions toward understanding disease pathogenesis and the development of new therapies.
Topics: Anemia; Animals; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Gen | 2019 |
3 other studies available for phenobarbital and Hepatic Porphyria
| Article | Year |
|---|---|
Assessment of porphyrogenicity of drugs and chemicals in selected hepatic cell culture models through a fluorescence-based screening assay.
Topics: Cell Culture Techniques; Heme; Hepatocytes; Humans; Liver; Norgestrel; Phenobarbital; Phenytoin; Por | 2022 |
Sustained enzymatic correction by rAAV-mediated liver gene therapy protects against induced motor neuropathy in acute porphyria mice.
Topics: Animals; Dependovirus; Female; Genetic Therapy; Genetic Vectors; Humans; Hydroxymethylbilane Synthas | 2011 |
Zinc mesoporphyrin represses induced hepatic 5-aminolevulinic acid synthase and reduces heme oxygenase activity in a mouse model of acute hepatic porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Animals; Arginine; Cytosol; Drug C | 2001 |