Page last updated: 2024-11-02

phenobarbital and Hemorrhage

phenobarbital has been researched along with Hemorrhage in 23 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Hemorrhage: Bleeding or escape of blood from a vessel.

Research Excerpts

ExcerptRelevanceReference
" The hypothesis is that the above mentioned chemicals can be responsible for a vitamin K deficiency in the babies resulting in a bleeding analogous with phenobarbital."3.67Dioxins and furans in the mother and possible effects on the fetus and newborn breast-fed baby. ( Koppe, JG, 1989)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199023 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DECSI, L1
KARACADAG, S1
KLOTZ, AP1
EVANS, RE1
LEAKE, D1
RYDER, RJ1
WANSEL, H1
Taylor, PJ1
Gelman, S1
Rimerman, V1
Fowler, KC1
Bishop, SP1
Bradley, EL1
Traggis, DG1
Maunz, DL1
Baroudy, R1
DiSabatino, CA1
Clyne, LP1
Malawista, SE1
Couchot, J1
Petit, J1
Pierrot, B1
Bayart, F1
Walker, W1
Vargas, GC1
Pildes, RS1
Vidyasagar, D1
Keith, LG1
Biale, Y1
Lewenthal, H1
Aderet, NB1
Koppe, JG1
Shojania, AM1
Grewar, D1
Sorbie, J1
Hamilton, DL1
Valberg, LS1
Fang, VS1
Tashjian, AH1
Szabo, S1
Selye, H1
Wilson, SM1
Owen, M1
Duff, TB1
Malcolm-Smith, NA1
Lucey, JF1
Cumming, JF1
McClung, HW1
Mannering, GJ1
Brody, BB1
MacDonald, MG1
Robinson, DS1

Reviews

1 review available for phenobarbital and Hemorrhage

ArticleYear
Haemolytic anaemia in the newborn infant.
    Clinics in haematology, 1975, Volume: 4, Issue:1

    Topics: ABO Blood-Group System; Amniocentesis; Antibodies; Blood Group Incompatibility; Blood Transfusion, I

1975

Trials

1 trial available for phenobarbital and Hemorrhage

ArticleYear
Operative blood loss in guillotine tonsillectomy and adenoidectomy in children: a comparison of three premedicant drugs.
    British journal of anaesthesia, 1973, Volume: 45, Issue:1

    Topics: Adenoidectomy; Blood Volume; Body Weight; Child; Child, Preschool; Colorimetry; Diazepam; Female; He

1973

Other Studies

21 other studies available for phenobarbital and Hemorrhage

ArticleYear
[Combined effect of luminal sodium and analeptics on phosphate ester formation or on respiratory chain phosphorylation of rat brain homogenates].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1957, Volume: 230, Issue:6

    Topics: Animals; Brain; Central Nervous System Stimulants; Electron Transport; Hemorrhage; Oxidative Phospho

1957
SIDE EFFECTS AND COMPLICATIONS OF GASTRIC FREEZING.
    JAMA, 1964, Jun-29, Volume: 188

    Topics: Biomedical Research; Chlorpromazine; Cryosurgery; Duodenal Ulcer; Electrocardiography; Fever; Freezi

1964
BLEEDING IN A HEMOPHILIAC AFTER INFERIOR ALVEOLAR NERVE BLOCK.
    Journal of the American Dental Association (1939), 1964, Volume: 69

    Topics: Anesthesia; Anesthesia, Conduction; Anesthesia, Dental; Antigen-Antibody Reactions; Factor VIII; gam

1964
HAEMORRHAGE ASSOCIATED WITH THROMBOCYTOPENIA IN MEGALOBLASTIC ANAEMIA.
    Journal of the Irish Medical Association, 1964, Volume: 55

    Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Blood Platelet Disorders; Drug Therapy; Epilepsy;

1964
[SPASMO-DOLVIRAN OF THE "BAYER" LEVERKUSEN FIRM. TEST IN PRACTICE].
    Deutsches medizinisches Journal, 1964, Jun-20, Volume: 15

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Caffeine; Codeine; Drug Therapy; Gallbladder Dis

1964
Hemorrhage while on anticoagulant therapy precipitated by drug interaction.
    Arizona medicine, 1967, Volume: 24, Issue:8

    Topics: Aged; Coumarins; Diazepam; Drug Synergism; Female; Glutethimide; Hemorrhage; Humans; Male; Middle Ag

1967
The effect of halothane, isoflurane, and blood loss on hepatotoxicity and hepatic oxygen availability in phenobarbital-pretreated hypoxic rats.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:11

    Topics: Animals; Chemical and Drug Induced Liver Injury; Halothane; Hemorrhage; Isoflurane; Liver; Liver Cir

1984
Splenic hemorrhage in a neonate of a mother on anticonvulsant therapy.
    Journal of pediatric surgery, 1984, Volume: 19, Issue:5

    Topics: Female; Hemorrhage; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Co

1984
A circulating anticoagulant directed against factor XIa in systemic lupus erythematosus.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:10

    Topics: Adult; Aspirin; Blood Coagulation Disorders; Blood Coagulation Tests; Factor XI; Female; Hemorrhage;

1979
[Fetal hemorrhage in the newborn infant of an epileptic mother treated with phenobarbital].
    La Nouvelle presse medicale, 1979, Jan-20, Volume: 8, Issue:3

    Topics: Adult; Epilepsy; Female; Hemorrhage; Humans; Infant, Newborn; Male; Phenobarbital; Pregnancy

1979
Effect of maternal heroin addiction on 67 liveborn neonates. Withdrawal symptoms, small body size, and small head circumference were frequent findings.
    Clinical pediatrics, 1975, Volume: 14, Issue:8

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Birth Weight; Blood Glucose; Cephalomet

1975
Congenital malformations due to anticonvulsive drugs.
    Obstetrics and gynecology, 1975, Volume: 45, Issue:4

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Ord

1975
Dioxins and furans in the mother and possible effects on the fetus and newborn breast-fed baby.
    Acta paediatrica Scandinavica. Supplement, 1989, Volume: 360

    Topics: Adult; Dioxins; Female; Furans; Hemorrhage; Humans; Infant, Newborn; Milk, Human; Phenobarbital; Pre

1989
Hypoprothrombinemic hemorrhage due to cholestyramine therapy.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1986, Mar-15, Volume: 134, Issue:6

    Topics: Bile Duct Diseases; Child, Preschool; Cholestyramine Resin; Female; Hemorrhage; Humans; Hypoprothrom

1986
Effect of various factors on iron absorption in mice with X-linked anaemia.
    British journal of haematology, 1974, Volume: 27, Issue:4

    Topics: Administration, Oral; Anemia, Hypochromic; Animals; Ascorbic Acid; Biological Transport; Body Weight

1974
Studies on the role of the liver in the metabolism of parathyroid hormone. I. Effects of partial hepatectomy and incubation of the hormone with tissue homogenates.
    Endocrinology, 1972, Volume: 90, Issue:5

    Topics: Adrenal Glands; Adrenalectomy; Animals; Antigens; Aprotinin; Calcium; Culture Techniques; Female; He

1972
Effect of phenobarbital and steroids on the adrenal apoplexy produced by acrylonitrile in rats.
    Endocrinologia experimentalis, 1972, Volume: 6, Issue:3

    Topics: Acrylates; Adrenal Cortex Hormones; Adrenal Gland Diseases; Animals; Biotransformation; Disease Mode

1972
Rare diseases, old drug, new knowledge.
    Pediatrics, 1973, Volume: 51, Issue:6

    Topics: Animals; Bilirubin; Epilepsy; Female; Hemorrhage; Humans; Infant, Newborn; Infant, Newborn, Diseases

1973
The effect of hemorrhage on the rate of hexobarbital biotransformation in the dog.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 178, Issue:3

    Topics: Aniline Compounds; Animals; Biotransformation; Cytochromes; Dogs; Enzyme Induction; Female; Hemorrha

1971
The effect of drugs on clinical laboratory determinations.
    Clinical chemistry, 1971, Volume: 17, Issue:5

    Topics: 17-Ketosteroids; Chemistry, Clinical; Drug Antagonism; Drug Synergism; Drug Therapy; Hemorrhage; Hum

1971
Clinical observations of possible barbiturate interference with anticoagulation.
    JAMA, 1968, Apr-08, Volume: 204, Issue:2

    Topics: Adolescent; Adult; Aged; Anticoagulants; Barbiturates; Coumarins; Enzyme Induction; Female; Hemorrha

1968