Page last updated: 2024-11-02

phenobarbital and Hematologic Diseases

phenobarbital has been researched along with Hematologic Diseases in 9 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Hematologic Diseases: Disorders of the blood and blood forming tissues.

Research Excerpts

ExcerptRelevanceReference
"Phenobarbital may cause hyperactivity, behavioral problems, sedation, and even dementia; these effects are dose related to some extent."5.27Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy. ( Iivanainen, M; Savolainen, H, 1983)
"Phenobarbital may cause hyperactivity, behavioral problems, sedation, and even dementia; these effects are dose related to some extent."1.27Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy. ( Iivanainen, M; Savolainen, H, 1983)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Scott, TN1
Bailin, HG1
Jutkowitz, LA1
Scott, MA1
Lucidi, CA1
Bersan, E1
Volk, HA1
Ros, C1
De Risio, L1
Thomson, C1
HAWKINS, CF1
MEYNELL, MJ1
Iivanainen, M1
Savolainen, H1
Kellaway, GS1
McCrae, E1
Pochedly, C1
Ente, G1
Fromke, VL1
Miller, D1
Wierzbowska, A1
Radomska, M1
Kolodziej, A1

Reviews

2 reviews available for phenobarbital and Hematologic Diseases

ArticleYear
Adverse hematologic effects of drugs.
    Pediatric clinics of North America, 1972, Volume: 19, Issue:4

    Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents

1972
Constitutional hepatic dysfunction (CHD; Gilbert's disease); a review with special reference to a characteristic increase and prolongation of the hyperbilirubinemic response to nicotinic acid.
    Medicine, 1972, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Anemia, Hemolytic, Congenital; Bilirubin; Fe

1972

Other Studies

7 other studies available for phenobarbital and Hematologic Diseases

ArticleYear
Bone marrow, blood, and clinical findings in dogs treated with phenobarbital.
    Veterinary clinical pathology, 2021, Volume: 50, Issue:1

    Topics: Anemia; Animals; Bone Marrow; Dog Diseases; Dogs; Hematologic Diseases; Phenobarbital

2021
Phenobarbitone-induced haematological abnormalities in idiopathic epileptic dogs: prevalence, risk factors, clinical presentation and outcome.
    The Veterinary record, 2014, Sep-13, Volume: 175, Issue:10

    Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Epilepsy; Female; Hematologic Diseases; Male; Phenobar

2014
Monitoring side effects of antiepileptic drugs.
    The Veterinary record, 2014, Sep-13, Volume: 175, Issue:10

    Topics: Animals; Anticonvulsants; Dog Diseases; Epilepsy; Female; Hematologic Diseases; Male; Phenobarbital

2014
Macrocytosis and macrocytic anaemia caused by anticonvulsant drugs.
    The Quarterly journal of medicine, 1958, Volume: 27, Issue:105

    Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Erythrocytes; Hematologic Diseases; Humans; Hydantoins;

1958
Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 97

    Topics: Abnormalities, Drug-Induced; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Endocrine Syst

1983
Intensive monitoring for adverse drug effects in patients discharged from acute medical wards.
    The New Zealand medical journal, 1973, Dec-26, Volume: 78, Issue:505

    Topics: Adolescent; Adult; Age Factors; Aged; Drug Interactions; Drug Therapy, Combination; Drug-Related Sid

1973
[Hematological control in the treatment of epilepsy].
    Neurologia i neurochirurgia polska, 1971, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Epilepsy; Female; Folic Acid; Hematolo

1971