phenobarbital has been researched along with Hematologic Diseases in 9 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Hematologic Diseases: Disorders of the blood and blood forming tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital may cause hyperactivity, behavioral problems, sedation, and even dementia; these effects are dose related to some extent." | 5.27 | Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy. ( Iivanainen, M; Savolainen, H, 1983) |
| "Phenobarbital may cause hyperactivity, behavioral problems, sedation, and even dementia; these effects are dose related to some extent." | 1.27 | Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy. ( Iivanainen, M; Savolainen, H, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Scott, TN | 1 |
| Bailin, HG | 1 |
| Jutkowitz, LA | 1 |
| Scott, MA | 1 |
| Lucidi, CA | 1 |
| Bersan, E | 1 |
| Volk, HA | 1 |
| Ros, C | 1 |
| De Risio, L | 1 |
| Thomson, C | 1 |
| HAWKINS, CF | 1 |
| MEYNELL, MJ | 1 |
| Iivanainen, M | 1 |
| Savolainen, H | 1 |
| Kellaway, GS | 1 |
| McCrae, E | 1 |
| Pochedly, C | 1 |
| Ente, G | 1 |
| Fromke, VL | 1 |
| Miller, D | 1 |
| Wierzbowska, A | 1 |
| Radomska, M | 1 |
| Kolodziej, A | 1 |
2 reviews available for phenobarbital and Hematologic Diseases
| Article | Year |
|---|---|
Adverse hematologic effects of drugs.
Topics: Anemia, Hemolytic; Anemia, Macrocytic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents | 1972 |
Constitutional hepatic dysfunction (CHD; Gilbert's disease); a review with special reference to a characteristic increase and prolongation of the hyperbilirubinemic response to nicotinic acid.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Anemia, Hemolytic, Congenital; Bilirubin; Fe | 1972 |
7 other studies available for phenobarbital and Hematologic Diseases
| Article | Year |
|---|---|
Bone marrow, blood, and clinical findings in dogs treated with phenobarbital.
Topics: Anemia; Animals; Bone Marrow; Dog Diseases; Dogs; Hematologic Diseases; Phenobarbital | 2021 |
Phenobarbitone-induced haematological abnormalities in idiopathic epileptic dogs: prevalence, risk factors, clinical presentation and outcome.
Topics: Animals; Anticonvulsants; Dog Diseases; Dogs; Epilepsy; Female; Hematologic Diseases; Male; Phenobar | 2014 |
Monitoring side effects of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Dog Diseases; Epilepsy; Female; Hematologic Diseases; Male; Phenobarbital | 2014 |
Macrocytosis and macrocytic anaemia caused by anticonvulsant drugs.
Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Erythrocytes; Hematologic Diseases; Humans; Hydantoins; | 1958 |
Side effects of phenobarbital and phenytoin during long-term treatment of epilepsy.
Topics: Abnormalities, Drug-Induced; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Endocrine Syst | 1983 |
Intensive monitoring for adverse drug effects in patients discharged from acute medical wards.
Topics: Adolescent; Adult; Age Factors; Aged; Drug Interactions; Drug Therapy, Combination; Drug-Related Sid | 1973 |
[Hematological control in the treatment of epilepsy].
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Epilepsy; Female; Folic Acid; Hematolo | 1971 |