phenobarbital has been researched along with Heart Septal Defects, Ventricular in 4 studies
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Heart Septal Defects, Ventricular: Developmental abnormalities in any portion of the VENTRICULAR SEPTUM resulting in abnormal communications between the two lower chambers of the heart. Classification of ventricular septal defects is based on location of the communication, such as perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular defect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenobarbital was observed to produce cardiovascular malformations in embryonic chicks." | 1.27 | The teratogenic effect of phenobarbital on the embryonic chick heart. ( Bruyere, HJ; Gilbert, EF; Matsuoka, R; Nishikawa, T; Takagi, Y, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Panduranga, P | 1 |
| Mukhaini, M | 1 |
| Koie, H | 1 |
| Kurotobi, EN | 1 |
| Sakai, T | 1 |
| Nishikawa, T | 1 |
| Bruyere, HJ | 1 |
| Takagi, Y | 1 |
| Gilbert, EF | 1 |
| Matsuoka, R | 1 |
| Halbrecht, I | 1 |
| Komlos, L | 1 |
| Shabtay, F | 1 |
| Solomon, M | 1 |
| Böök, JA | 1 |
4 other studies available for phenobarbital and Heart Septal Defects, Ventricular
| Article | Year |
|---|---|
A rare type of Gerbode defect.
Topics: Adolescent; Drug Combinations; Heart Septal Defects, Atrial; Heart Septal Defects, Ventricular; Huma | 2011 |
Double-chambered right ventricle in a dog.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Chloramphenicol; Dog Disea | 2000 |
The teratogenic effect of phenobarbital on the embryonic chick heart.
Topics: Abnormalities, Drug-Induced; Animals; Arrhythmias, Cardiac; Chick Embryo; Dose-Response Relationship | 1986 |
Triploidy 69, XXX in a stillborn girl.
Topics: Adult; Asthma; Chromatids; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-1 | 1973 |