Page last updated: 2024-11-02

phenobarbital and Hearing Loss

phenobarbital has been researched along with Hearing Loss in 2 studies

Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.

Hearing Loss: A general term for the complete or partial loss of the ability to hear from one or both ears.

Research Excerpts

ExcerptRelevanceReference
"Bumetanide, an inhibitor of the sodium-potassium-chloride cotransporter-1, has been suggested as an adjunct to phenobarbital for treating neonatal seizures."9.41Effects of bumetanide on neonatal seizures: A systematic review of animal and human studies. ( Athikarisamy, S; Farhat, A; Ghosh, S; Nagarajan, L; Rakshasbhuvankar, A; Rao, S, 2023)
"Exposure to toluene causes a marked hearing loss in rats, and this effect has been observed in some human solvent abusers."7.68The hearing loss associated with exposure to toluene is not caused by a metabolite. ( Gordon, R; Kassay, K; Kuiper, H; Pryor, G; Rebert, C, 1991)
"Bumetanide, an inhibitor of the sodium-potassium-chloride cotransporter-1, has been suggested as an adjunct to phenobarbital for treating neonatal seizures."5.41Effects of bumetanide on neonatal seizures: A systematic review of animal and human studies. ( Athikarisamy, S; Farhat, A; Ghosh, S; Nagarajan, L; Rakshasbhuvankar, A; Rao, S, 2023)
"Exposure to toluene causes a marked hearing loss in rats, and this effect has been observed in some human solvent abusers."3.68The hearing loss associated with exposure to toluene is not caused by a metabolite. ( Gordon, R; Kassay, K; Kuiper, H; Pryor, G; Rebert, C, 1991)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Rao, S1
Farhat, A1
Rakshasbhuvankar, A1
Athikarisamy, S1
Ghosh, S1
Nagarajan, L1
Pryor, G1
Rebert, C1
Kassay, K1
Kuiper, H1
Gordon, R1

Reviews

1 review available for phenobarbital and Hearing Loss

ArticleYear
Effects of bumetanide on neonatal seizures: A systematic review of animal and human studies.
    Seizure, 2023, Volume: 111

    Topics: Aminoglycosides; Animals; Anticonvulsants; Bumetanide; Epilepsy; Hearing Loss; Humans; Infant; Infan

2023

Other Studies

1 other study available for phenobarbital and Hearing Loss

ArticleYear
The hearing loss associated with exposure to toluene is not caused by a metabolite.
    Brain research bulletin, 1991, Volume: 27, Issue:1

    Topics: Acoustic Stimulation; Animals; Auditory Perception; Biotransformation; Drinking Behavior; Hearing; H

1991